Senior Scientist, Quantitative Pharmacology and Pharmacometrics

At Genmab, we are dedicated to building extra[not]ordinary futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.Does this inspire you and feel like a fit? Then we would love to have you join us!RoleThe Senior Scientist, Quantitative Pharmacology and Pharmacometrics will contribute, under guidance, clinical pharmacology and pharmacometrics expertise to research and development programs, working closely with cross-functional program teams. In this role, the scientist will support the development, validation, execution, and interpretation of population PK, exposure-response, PK-PD, PBPK, time-to-event, survival, and disease progression modeling analyses to inform dose selection, regimen optimization, clinical trial design, and model-informed drug development across Genmab’s pipeline.This is an exciting opportunity to be part of a passionate, high-profile, high-impact Clinical Pharmacology & Quantitative Science team, and to work in a highly dynamic and collaborative setting, with opportunities for professional development.Work arrangement: This role offers flexibility to work away from the office for 20%–40% of a typical schedule. Employees may use this work schedule in increments of single days or multiple consecutive days, provided it does not exceed 40% within a 60-day period, and is approved by the hiring manager.ResponsibilitiesPlan, conduct, document, and quality-check routine pharmacometrics analyses under guidance from senior team members.Contribute to the development, validation, execution, and interpretation of population PK, exposure–response, PK-PD, PBPK, time-to-event, survival, disease progression models to support dose selection, regimen optimization, and trial design.Prepare model code, diagnostics, tables, figures, reports, and presentations in a reproducible and well-documented manner.Communicate the pharmacometrics analysis results to program teams to support data-driven decision making process.Contribute quantitative clinical pharmacology and pharmacometrics content for regulatory submissions, including INDs, CTAs, and BLAs, and support responses to agency questions on modeling and simulation deliverables.Support the advancement of quantitative clinical pharmacology and pharmacometrics capabilities, including model-informed drug development approaches, tools, workflows, and best practices.RequirementsPhD in Clinical Pharmacology, Pharmacokinetics, Pharmaceutical Science or related discipline.Approximately 2+ years of relevant experience applying quantitative methods to drug development questions; Relevant academic, internship, postdoctoral, or industry experience may be considered.Hands-on experience with pharmacometrics and data analysis tools such as NONMEM, Monolix, R, or similar software.Ability to work with clinical and nonclinical data, perform model diagnostics, and generate clear, reproducible analyses.Understanding of antibody therapeutics development, oncology, or immunology is considered beneficial.Excellent written, verbal, and interpersonal communication skills, with the ability to explain quantitative concepts to multidisciplinary audiences.Strong problem-solving skills, scientific curiosity, attention to detail, and the ability to thrive in a collaborative, fast-paced biotechnology environment.For US based candidates, the proposed salary band for this position is as follows:$138,720.00---$208,080.00The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives. When you join Genmab, you’re joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:401(k) Plan: 100% match on the first 6% of contributionsHealth Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insuranceVoluntary Plans: Critical illness, accident, and hospital indemnity insuranceTime Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leaveSupport Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being supportAdditional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses Further details on eligibility for compensation and benefits based on role will be provided during the recruitment processAbout GenmabGenmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO) antibody medicines.Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com).Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.Job SummaryJob number: R17461Date posted : 2026-08-10Profession: Research & DiscoveryEmployment type: Full time