Staff Software Engineer
$210k - $260kDavid Joseph & Company
Job Description
Job Description
Staff Software Engineer
Our client is a seed-stage healthcare/life-sciences company building AI agents that automate clinical trial workflows — attacking one of the biggest bottlenecks in drug development. Backed by $7M+ in funding, the platform is already used across 400+ research sites. This is a founding tech-lead role on a small, high-impact engineering team.
The role: A hands-on Staff Software Engineer (8+ yrs) to be the technical anchor of a small team — writing and reviewing code daily while mentoring three junior engineers and establishing engineering best practices, and partnering with product, customer success, and founders to ship zero-to-one AI-powered products.
Responsibilities
- Own and build AI-powered products end-to-end (agentic workflows, LLM features with production evals)
- Technical lead and mentor for three junior engineers; set best practices for code review and process
- Partner with CTO, PM, and customer success to shape zero-to-one products
- Architect and deliver full-stack apps across frontend, backend, infra, and data pipelines
Must-have
- Tech lead / technical anchor experience on an engineering team
- Full-stack product engineer who owns features end-to-end (backend-leaning generalists welcome)
- Mentor / bar-raiser able to establish engineering best practices
- 8–15 yrs full-stack product engineering, building AI/LLM features
- Zero-to-one, customer-facing product background (not deep infra)
- Recent (1–2 yrs) hands-on shipping of LLM features / AI agents in production
Nice-to-have
- Mix of startup (seed–Series B, founding/early hire) and larger-company experience
- CS degree or equivalent
- Production AI evals / LLM observability (LangSmith, Braintrust, W multi-step agentic pipelines
- Genuine interest in bio, life sciences, or healthcare
Compensation & logistics
- Base salary: $210K–$260K, flexible for exceptional candidates
- Equity: 1–1.5%
- Full-time, hybrid: 3 days/week in-office (Mon, Tue, Thu), Financial District, San Francisco
- Visa: open to transfers (e.g., OPT, H-1B transfers); no new sponsorships
- Interview process: 3 steps — 30-min intro call, virtual system design interview, final on-site (technical + behavioral + team lunch)
$200k - $250k
...About Us At 3Y Health, we are building AI-driven software to empower healthcare providers and solve the overwhelming administrative complexity... ..., and 8VC. About the Role We are seeking a Frontend Engineer to help us craft intuitive, high-performance user interfaces...SuggestedFull timeWork experience placementPrivate practiceWork at office3Y Health
San Francisco, CA1 day ago$185k - $215k
...scope of payments at Quizlet. We are at the intersection of engineering, business, and compliance, which means you’ll have the chance... ...drive key business outcomes. About the Role: As a Staff Software Engineer on the Payments team, you will play a pivotal role...SuggestedFull timeWork at officeQuizlet
San Francisco, CA1 day ago- ...sales into a scalable science. About the Role Sales software was built for humans. But we believe most sales work will be... ...hours a day across these different product lines. We're hiring a staff engineer to help set a unified technical direction for the entire team...SuggestedFull timeWork at office3 days per week
Nooks
San Francisco, CA1 day ago - ...more about our AI interview philosophy and how we use AI in our recruiting process here . Pinterest's performance marketing engineering team owns the end-to-end systems that turn marketing dollars into measured user growth spanning attribution, bidding, budget optimization...SuggestedRemote jobFull timeWork at officeRelocationRelocation packageShift work
Pinterest
San Francisco, CA1 day ago - ...you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . As a Staff Software Engineer at Pinterest, you will help define and drive the technical direction of the web development layer that product engineers...SuggestedFull timeWork at officeRelocationRelocation package
Pinterest
San Francisco, CA1 day ago $189k - $210k
...assessed during the interview process. About the Role: As an engineer on the Developer Productivity - Async team, you will work on... ...to lifting each other up and amplifying the craft of software development at scale. Here’s what you’ll do day-to-day:...Full timeWork at officeLocal areaRemote work2 days per week3 days per weekGusto
San Francisco, CA1 day ago- ...personalized pain reprocessing therapy and mindfulness interventions. You will bridge the gap between clinical science and software engineering, building the engine that helps millions of members retrain how their nervous systems process pain. What You'll Accomplish...Full timeImmediate start
Hinge Health, Inc.
San Francisco, CA1 day ago $210k - $260k
...Staff Software Engineer, Full Stack Location: Hybrid - San Francisco OR Palo Alto Office Tuesday/Thursday. Flexibility for remote work if you are not within a commutable distance to either office. The difference you will make We are looking for a Staff Fullstack...Full timePart timeH1bWork at officeImmediate startRemote workFlexible hoursMidi Health
San Francisco, CA1 day ago- ...more information, visit The Role We’re looking for a Staff Full-Stack Engineer to lead end-to-end delivery and drive technical direction... ...you own. What You’ll Bring ~8+ years of professional software engineering experience, including demonstrated Staff-level...Full timeFlexible hours
Orum
San Francisco, CA1 day ago $224k - $264k
...customer satisfaction, across a complex, regulated domain. As a Staff Engineer in this organization, you'll operate across several product... ...field, or equivalent practical experience ~10+ years of software development experience and 3+ years experience in a project...Full timeWork at officeLocal areaRemote workRelocationFlexible hours3 days per weekCheckr
San Francisco, CA1 day ago$220k - $250k
...team that believes in each other, come build with us at Crusoe. About the Role: We are actively seeking an exceptional Staff Software Engineer for our cloud software team who will contribute to the operations of our cutting-edge infrastructure. Your expertise will be...Full timeTemporary workCrusoe
San Francisco, CA1 day ago$200k - $250k
...customer. Kodiak is also leveraging its commercial self-driving software to develop, test and deploy autonomous capabilities for the U.S. Department of Defense. Kodiak is recruiting a Staff Software Engineer to join our Planning team and advance the Kodiak Driver’s...Full timeTemporary workWork at officeVisa sponsorshipFlexible hoursKodiak
San Francisco, CA1 day ago$2,000 per month
...pathologically unfair at worst. Our mission is to reimagine the world of data with you. About The Role As a Principal/Staff Software Engineer , you will help build out the next generation data platform to support decentralized analytical and ML workloads, which...Full timeNextdata
San Francisco, CA1 day ago$240k - $270k
...platform on the modern data architecture. Hence, we are growing the engineering team and looking for engineers who are excited to solve... ...and workflows use cases on top of modern warehouses Build software using the latest developer tools and using programming languages...Full timeWork at officeFlexible hoursSigma Computing
San Francisco, CA1 day ago- ...done. The Role We are seeking a skilled and motivated engineer with a strong interest in and background in front-end web development... ...prolifically with AI assistance and the mature judgment of a staff engineer. Enjoy a fast moving, dynamic startup environment....Full timeFlexible hours
Parkade
San Francisco, CA1 day ago - ...increase the speed and capacity of buildout, starting with data centers. About the Role At Watney, full stack engineers own our software ecosystem end-to-end, meaning you will regularly cross the boundary between high-throughput backend infrastructure, enterprise...Full time
Watney
San Francisco, CA1 day ago - ...Lunar is a stealth technology company building a new type of software platform for health systems. We are on a mission to... ..., ICUs, and Operating Rooms. We are looking for a Staff Product Engineer who's excited to tackle some of the hardest technical problems...Full time
Lunar, Llc
San Francisco, CA1 day ago $241k - $284k
...ensuring web reliability and performance at scale. As a Staff Frontend Engineer on the App Platform team, you will play a leading technical... ...AI-powered tooling and practices into how we build and ship software. Our mission is to provide the foundation that helps every...Full timeWork at officeHome officeFlexible hours3 days per weekGlossgenius
San Francisco, CA1 day ago- ...’re a team of AI researchers, designers, growth experts, and engineers rethinking human-computer interaction from the ground up. We... ...firms and other well-known angels. About the Role As a Staff Software Engineer at Wispr, you’ll play a crucial role in building the...Full time
Wispr Flow
San Francisco, CA1 day ago - ...this role, you will build the product that gets stuff built. You'll work closely with engineers, designers, and end-users to accelerate our product development. As a staff-level software engineer at Pulley, you will: Own problem areas, not just features—define the...Full time
Pulley
San Francisco, CA1 day ago - ...time, with the right message, through the right channel. As a Staff Engineer, you will lead the technical architecture of our unified... ...practices for CI/CD, automated testing, and monitoring for both software services and ML model performance in production. Mentorship...Full timeInternshipWork at officeLocal areaImmediate startRemote workWorldwide3 days per week
Hinge Health, Inc.
San Francisco, CA1 day ago $163k - $204k
...process. About the Team: We’re a small group of talented engineers, designers, data scientists, and product managers working to... ...Operations, and other cross-functional teams. Support the software platform that powers multiple 1st and 3rd party products and serves...Full timeWork at officeLocal areaRemote work2 days per week3 days per weekGusto
San Francisco, CA1 day ago- ...coding tools, internal systems, and the entire software development lifecycle. When we are successful, engineers across Plaid will delegate lower-leverage work to... ...Plaid’s operations. Role Description: As a Staff Software Engineer on the Intelligent Tooling team...Full timeWork experience placementLocal area
Plaid Inc.
San Francisco, CA1 day ago $208.73k - $253k
...high-impact group charged with fueling the future of Crusoe’s engineering muscle. We’re responsible for critical developer tools and infrastructure... ..., you will define the future state of Crusoe’s evolving software development efforts and eliminate the friction that stands...Full timeTemporary workCrusoe
San Francisco, CA1 day ago$194k - $243k
...can make us better with their unique experiences. The Engineering Opportunity Okta's Workforce Identity Cloud (WIC) secures... ...and reliable for every customer. We are seeking a Staff Back-End Software Engineer to lead technical initiatives and own the reliability...Permanent employmentFull timeLocal areaWorldwideFlexible hoursOkta
San Francisco, CA1 day ago- ...About Flow Flow Engineering is an AI-native requirements platform for modern engineering organizations, enabling hardware teams to... ...with speed and rigor. About the role Flow is seeking staff software engineers to build AI-powered capabilities that help teams author...Full timeFlexible hours
Flow Engineering
San Francisco, CA1 day ago - ...quality of everything around you. Our stack is Node, TypeScript, React, and Python... for now. Who You Are ~3+ years of software engineering experience , with meaningful time in production systems at scale. ~ Deep full-stack fluency — comfortable owning a...Full timeWork at officeRelocation package
Petra Security
San Francisco, CA1 day ago - ...Lightspeed, with $41M raised. Our founder, Harpaul Sambhi, previously sold his first company to LinkedIn. About the Role As a Staff Software Engineer, you’ll shape the technical direction of Magical’s AI agent systems. You’ll drive product delivery, elevate engineering...Full timeWork at office
Magical
San Francisco, CA1 day ago $238k - $312k
...outcomes. We stay close to our customers — from leadership to engineers — and work together to solve real problems with urgency and... ...part of how we meet lawyers where they already work. As a Staff Software Engineer on this team, you’ll own critical backend systems that...Full timeWork at officeHarvey, Inc.
San Francisco, CA1 day ago$200k - $230k
...Job Title: Staff Software Engineer Company: Canopy, Inc. Location: SF Bay Area About Canopy At Canopy , we build technology that helps make healthcare environments safer for the people delivering care. Our connected safety platform powers real-time communication...Full timeCanopyworks
San Francisco, CA1 day ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Staff Software Engineer. Be the first to apply!
- software sales representative San Francisco, CA
- embedded software San Francisco, CA
- software applications developer San Francisco, CA
- entry level software sales San Francisco, CA
- software technology San Francisco, CA
- software implementation project manager San Francisco, CA
- software support San Francisco, CA
- government software San Francisco, CA
- software engineer - cloud services San Francisco, CA
- software qa San Francisco, CA