Principal Investigator

Focus: Liver & Metabolic Health / Clinical Research Position Overview We are seeking an experienced Principal Investigator (MD or DO) to lead clinical research operations at a growing research site in Gilbert, AZ. The PI will have primary responsibility for the clinical and regulatory oversight of active industry-sponsored clinical trials, initially overseeing studies focused on liver and metabolic health . This is a full-time, on-site research leadership opportunity. Candidates with a Gastroenterology or Hepatology background may also have the opportunity to negotiate partial clinical practice time through an affiliated gastroenterology practice. Key Responsibilities Serve as the Principal Investigator with overall responsibility for trial integrity, patient safety, protocol adherence, and regulatory compliance. Provide medical oversight across all active clinical trials and ensure studies are conducted in accordance with GCP, FDA regulations, IRB requirements, and study protocols . Supervise and provide clinical direction to Sub-Investigators, Clinical Research Coordinators, and Research Assistants . Review and sign off on medical documentation, laboratory results, adverse events, and protocol-required assessments. Conduct high-level patient evaluations, screening approvals, and follow-up study visits. Participate in patient visits primarily during morning fasting windows . Partner with the current/retiring Principal Investigator during a short transition period to assume responsibility for ongoing studies and facilitate a smooth handoff with sponsors and research staff. Collaborate with the research team to maintain strong study execution, patient safety, data quality, and regulatory compliance. Required Qualifications MD or DO degree. Previous experience serving as the Principal Investigator on at least 5 clinical studies . Demonstrated experience providing medical oversight of clinical research studies. Ability to work full-time and on-site in Gilbert, AZ . Preferred Qualifications Gastroenterology or Hepatology background preferred. Experience with Fatty Liver Disease, MASH/MASLD, or metabolic health studies. Previous experience with GLP-1 clinical trials . Candidates without a GI/Hepatology background are encouraged to apply if they meet the PI experience requirements and are interested in a 100% clinical research-focused role . Full-time, on-site position in Gilbert, AZ. Approximately 8-hour workday . Patient visits typically begin around 7:30–8:00 AM due to fasting study requirements. Clinic operations generally conclude around 5:00 PM . Opportunity Highlights Lead a portfolio of liver and metabolic health clinical trials . Take on a key leadership role at the research site. Work alongside an experienced research team during a structured PI transition. GI/Hepatology physicians: Opportunity to discuss incorporating partial clinical practice through the affiliated gastroenterology practice. General physicians: Opportunity to focus entirely on clinical research and serve as the site's full-time research leader. #J-18808-Ljbffr