Postdoctoral Research Associate - Chemical Biology & Therapuetics

Postdoctoral Research Associate We are looking for a Postdoctoral Research Associate to join the lab of Taosheng Chen. The Chen Lab studies the chemical regulation of nuclear xenobiotic receptors (PXR, CAR) and the mechanism of selective modulation of drug‑metabolizing enzymes (CYP3A4, CYP3A5). The lab uses a hypothesis‑driven, technology‑enabled multidisciplinary approach to develop chemical probes, investigate biological mechanisms, and evaluate in vivo efficacy. Responsibilities Study the regulation of PXR and CAR or CYP3A4 and CYP3A5 by characterizing novel chemical probes (small‑molecule inhibitors or degraders) in biochemical, biophysical, cellular, and animal models. Work within a multidisciplinary team of biologists, medicinal chemists, and structural biologists to develop and test chemical probes. Contribute to or lead the team effort in designing experiments and interpreting data. Organize and prepare manuscripts for publication. Receive training in manuscript and grant writing and be encouraged to prepare and submit grant proposals. St. Jude is an Equal Opportunity Employer. #J-18808-Ljbffr St. Jude Children's Research Hospital, Inc.