Principal Scientist
Curie
Direct message the job poster from Curie.Bio A Curie.Bio portfolio company is looking for a Senior Polymer Chemist Consultant to lead and scale the polymer function for an early-stage, well-capitalized biotech company currently operating in stealth mode. This individual will serve as the internal expert in polymer chemistry and manufacturing, owning polymer development programs and CRO oversight. Key Responsibilities Independently interpret and guide polymer development data generated by CRO partners. Design and propose new experiments to meet development objectives. Act as the primary scientific liaison with a China-based CRO, including meetings, protocol review, and follow-up. Review technical documentation and ensure scientific rigor and alignment with program goals. Present clear, actionable recommendations to internal, cross-functional teams. Ideal Background PhD or equivalent experience in Polymer Chemistry, Organic Chemistry, or related field. Senior-level, hands‑on experience in controlled polymer synthesis and polymer development. Hands‑on RAFT polymerization experience. Knowledge in polymer characterization and analytical methods. Demonstrated ability to lead and scale polymer programs, including CRO oversight. Strong understanding of polymer development and CMC requirements as it relates to clinical manufacturing readiness. Experience working with global CROs and cross-time-zone teams is strongly preferred. Specification setting and documentation to support regulatory filings. Seniority level Director Employment type Contract Job function Science and Research Industries Pharmaceutical Manufacturing and Biotechnology Research #J-18808-Ljbffr
- ...A leading biotechnology company is seeking a Senior Principal Scientist to lead the bioanalytical strategy for antibody-siRNA conjugates. The successful candidate will oversee the execution of innovative assays and studies related to pharmacokinetics, ensuring collaboration...PrincipalRemote work
- ...Praxis Precision Medicines, Inc. is seeking a Principal Scientist in Analytical Development to lead efforts in advancing oligonucleotide-based therapeutics. This role offers remote work with travel as needed and involves significant collaboration across cross-functional...PrincipalRemote work
- ...The Arkema Group is seeking a Principal Scientist, Global Refrigerant Program Leader, to drive sustainable refrigerant initiatives and technology strategy. Located in the United States, the position involves leading the thermal management technology platform and liaising...Principal
- MSD Malaysia is seeking an Associate Principal Scientist in West Point, PA, to support our Live Virus Vaccines franchise. In this role, you will develop and implement analytical strategies, collaborate across multiple teams, and drive method alignment while ensuring exceptional...Principal
- A leading biotechnology company in New York City is seeking experienced machine learning scientists for its AI for Drug Discovery group. The role involves developing innovative models to transform drug discovery processes using various data sources. Candidates should have...Principal
- Legend Biotech is seeking a motivated Principal Scientist, Clinical Biomarker, with a focus on immunology and hematology. This role requires a Ph.D. and extensive experience in biotech or pharma, particularly in IO. You will lead clinical studies, collaborate across teams...PrincipalFor contractors
- Legend Biotech USA is seeking a Principal Scientist for Clinical Biomarker projects in Somerset, NJ. This role involves leading innovative clinical studies focused on hematological malignancies and collaborating on cross-functional project teams. The ideal candidate holds...PrincipalContract work
- A leading biotechnology company in Idaho is seeking a Senior Principal Scientist as a Project Toxicologist to lead nonclinical safety strategies. The role involves collaborating with project teams on drug development, managing safety programs, and mentoring fellow scientists...Principal
$160k - $190k
Immunai is seeking a Principal Scientist - Computational Biologist to innovate drug discovery methods in New York City. The role involves designing analytic pipelines, operationalizing approaches, and enhancing clinical trial success through AI. Required qualifications...Principal$169k - $195k
...Principal Scientist, Analytical Development – Drug Substance Remote Overview Who We Are: MapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics...PrincipalTemporary workRemote workFlexible hours$128.6k - $210k
Regeneron Pharmaceuticals, Inc is seeking a Principal Scientist to join their Precision Medicine Quantitative Biomarker team. This role focuses on the Oncology portfolio, handling exploratory analyses of multi-modal datasets and developing analytical tools. Ideal candidates...Principal$183.96k - $204.84k
...Senior Principal Scientist | Antibody-siRNA Bioanalytical & Biodistribution Strategy Lead page is loaded## Senior Principal Scientist | Antibody-siRNA Bioanalytical & Biodistribution Strategy Leadremote type: Remotelocations: United States - Remotetime type: Full timeposted...PrincipalFlexible hours$224k - $336k
...systems that are safe, reliable, and impactful in production. Job Description and Requirements ABOUT THE ROLE As a Principal Applied Scientist, Reliability, you will lead the design and validation of intelligent systems that customers can trust in high‑stakes...PrincipalRemote work$142.8k - $274.8k
...Modeling team, part of Microsoft AI Ads Engineering, to shape the future of advanced AI at web scale. In this role, the Principal Applied Scientist will design and implement state-of-the-art machine learning models and algorithms that power key systems within...PrincipalOngoing contractWork at officeLocal area$184.06k - $223.04k
...regarding the asset and disease biology Works with TM laboratory scientists and academic TLs to address nonclinical translational... ...application should be directed to Chat with Ripley. R1600104 : Senior Principal Scientist, Cardiovascular, Translational Development Company:...PrincipalHourly payFull timeTemporary workPart timeSummer workLive inLocal areaRemote workFlexible hoursShift work$234k - $250k
...matter - both for our audiences and our employees - and aim to leave a positive mark on culture. We are seeking a Principal Machine Learning Scientist to join the Core Science Group. This is a foundational leadership role designed for a visionary who wants to build...Principal$197.27k - $267.04k
...intersection of machine learning research, real world data, and production systems running in industrial environments. As Principal Applied Scientist, you lead the science on a major capability area inside the pod. You take ambiguous problems through hypothesis, method...PrincipalLocal area$218.8k - $295.9k
...Principal Applied Scientists in AWS Science of Security are dedicated to making AWS the best computing service in the world for customers who require advanced and rigorous solutions for security, privacy, and sovereignty. Key job responsibilities The successful...PrincipalFlexible hours$197.3k - $313.7k
...in the right place! Agentforce is the future of AI, and you are the future of Salesforce. Position Overview: As a Decision Scientist within the Data & Analytics organization, you will collaborate with cross-functional teams to measure agentic impact, influence leaders...Principal$166.77k - $202.09k
...Principal Scientist, Computational Biology Location: Cambridge, MA (no remote option). Responsibilities Perform computational research and integrative analyses on multimodal biological profiling datasets (e.g., transcriptomic, proteomics, single‐cell omics, spatial profiling...PrincipalHourly payTemporary workSummer workRemote workFlexible hours- A leading environmental innovation firm is seeking a Principal Environmental Scientist to transform product design with a focus on sustainability. This role involves research into low impact materials, conducting life cycle assessments, and educating teams on environmental...PrincipalFlexible hours
$228.7k - $309.4k
...vision for this intelligence layer, leading a team of applied scientists working across GenAI and predictive modeling. You will shape how... ...different modeling paradigms and data modalities to guide principal and senior scientists in their most challenging and strategic...PrincipalLocal areaFlexible hours$190k - $210k
...transformation into a leading technology and AI-driven company shaping the future of healthcare. JOB SUMMARY: We are seeking a Principal Applied Scientist to lead the research, development, and deployment of advanced machine learning and AI systems that power Claritev’s next...PrincipalTemporary workFlexible hours$144.2k - $288.4k
...Principal Decision Scientist For Commercial Pricing And Product We're building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you'll be surrounded by passionate colleagues who care...PrincipalHourly payFull timeTemporary workWork experience placementFlexible hours- Parexel International is seeking a Principal Scientist - Purification Chemist to work as a full-time employee at one of our clients in Rahway, NJ. This role requires expertise in chromatography, organic chemistry, or biochemistry for the purification of APIs and related...PrincipalFull time
$140k - $170k
Principal Scientist - Clinical & Clinical & Pharmacokinetics (Nutraceutical Ingredients) The key duties and responsibilities of the Principal Scientist will include the following: Lead the design, development, and execution of clinical studies to evaluate the efficacy...Principal- We are looking to fill a Principal Scientist - Purification Chemist position working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients located in Rahway, NJ . This position offers full benefits, sick time, 401K, paid holidays, and...PrincipalFull time
- Legend Biotech is seeking a Principal Scientist, Clinical Biomarker, Immunology, Immuno‑Oncology, & Hematology (Contractor) as part of the Research & Development team based in Somerset, NJ. Role Overview We are seeking a highly motivated and innovative Principal Scientist...PrincipalContract workFor contractorsLocal area
$147.8k - $274.4k
...power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative... ...coherent model for lab-in-the-loop drug discovery As a Principal Scientist Develop novel machine learning methods to answer challenging...PrincipalWork experience placementLocal areaWorldwideRelocation package- ...Select how often (in days) to receive an alert: Principal Scientist, Global Refrigerant Program Lead Job Location: Home Based, Home, US Employment Type: Regular Category: Research and Development Posting Date: Apr 14, 2026 Principal Scientist, Global Refrigerant Program...PrincipalPermanent employmentLocal areaWork from home
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