Biologics Process Research & Development , Senior Scientist

Biologics Process Research & Development (BPR&D) within our Company's Research Laboratories is on a mission to rapidly deliver biotherapeutics to patients by efficiently developing innovative, robust manufacturing processes and technologies. We work closely with colleagues in Discovery, Pre‑clinical, Early Development, Analytical, Formulation, and Commercial Manufacturing while providing an inclusive environment for all. Beyond process development for pipeline biologics, we innovate and build next generation biomanufacturing technologies such as continuous manufacturing, green and sustainable processes, and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field. Biologics Process Research & Development (BPR&D) includes three lab‑facing technical functional areas: Process Cell Sciences (PCS), Upstream and Downstream Process Development & Engineering. The latter two together form our Biologics’ Process Development (BPD) group. Responsibilities Develop innovative and disruptive technologies for next‑generation biologic manufacturing processes Apply rigorous scientific principles and data analyses to solve challenging problems related to developing robust, cost‑effective processes Design and characterize robust processes for delivering multi‑kilogram quantities of life‑changing medicines Design and conduct lab and/or pilot‑scale studies to support mechanistic understanding, scale‑up, and transfer of processes to manufacturing Collaborate effectively with cross‑functional teams to advance the biologics pipeline from early‑ to late‑stage development and represent your functional area in cross‑functional teams Partner with research and manufacturing divisions Train and mentor junior scientists in experimental design, execution, and data interpretation Contribute to a safe and compliant laboratory work environment Minimum Education Requirements Bachelor's Degree with 4 years, or Master's Degree with 3 years or PhD with 0+ years of relevant experience (or expected PhD graduation within 6 months from date of application) in Chemical Engineering, Biochemical Engineering, Biomedical Engineering, Biotechnology, Biochemistry, Biology, Microbiology, or related fields Required Experience and Skills Proven ability to design and execute hands‑on lab and/or in‑silico experiments Proficiency with statistical design and analysis tools Excellent communication skills, ability to work in matrixed teams and collaborate cross‑functionally Demonstrated ability to think critically with excellent problem‑solving and troubleshooting skills Relevant experience in upstream and/or downstream bioprocessing: upstream – recombinant protein expression, metabolic pathways, biochemistry, cell culture, basic bioreactor principles, mass transfer kinetics, and cell & molecular biology; downstream – protein properties and purification, chromatography, filtration, crystallization, precipitation, adsorption, mixing, etc. Preferred Experience and Skills History of external presentations and/or publications in peer‑reviewed journals Data science, modeling, machine learning, and artificial intelligence; proficiency with programming languages Evaluating and introducing novel technologies and analytical tools in process development and manufacturing Knowledge of protein biochemistry, biophysics, conjugation techniques Vector construction, genetic engineering, and systems biology Knowledge of cell‑line development for protein expression in mammalian systems and suspension cell culture Hands‑on experience with RNA and whole‑genome (re)sequencing, and bioinformatics analysis High‑throughput experimentation using automation platforms Familiarity with feed and media development for large‑scale recombinant protein expression in mammalian systems Knowledge of Quality by Design, Process Characterization and Control Strategy development Work Arrangement Hybrid work model: employees in office‑based positions in the U.S. will work a hybrid schedule of three total days on‑site per week (Monday‑Thursday, with Friday remote), unless business‑critical tasks require an on‑site presence. Facility‑based, manufacturing‑based, or research‑based positions require daily in‑person attendance. Remote positions are excluded. Compensation and Benefits Salary range: $117,000.00 – $184,200.00 (based on education, experience, geography, etc.). Eligible for annual bonus and long‑term incentive. Comprehensive benefits include medical, dental, vision, retirement 401(k), paid holidays, vacation, compassionate and sick days. Equal Employment Opportunity Statement As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. #J-18808-Ljbffr MSD Malaysia