Senior Software Engineer

Foresight Diagnostics is a molecular diagnostics company advancing non-invasive cancer detection through highly sensitive, cell-free DNA–based liquid biopsy technologies. Our proprietary methods, originally developed at Stanford University, are designed to enable earlier detection of smaller tumors and support more personalized, effective cancer treatment strategies.

We operate at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), translating rigorous scientific innovation into clinically meaningful solutions. As our organization has grown, we have built robust laboratory operations, cross‑functional collaboration, and scalable processes to support clinical development and long‑term commercial readiness.

Foresight Diagnostics offers a collaborative, high‑accountability work environment where quality, precision, and continuous improvement are core to how we operate. Team members have the opportunity to contribute to impactful programs, work alongside experienced scientific and operational leaders, and grow professionally within a well‑resourced and mission‑focused organization. Foresight Diagnostics is headquartered in Boulder, Colorado.

About the Role

We are seeking a Senior Full Stack Software Engineer with strong Python experience, frontend proficiency (preferably in React), and backend experience working with relational databases (PostgreSQL preferred). In this role, you will contribute to the design, development, and maintenance of full‑stack software solutions supporting research, product development, and clinical testing operations. A candidate with an understanding of NGS laboratory workflows and data management is preferred.

This position is onsite in Boulder, CO and is not eligible for remote or hybrid arrangements. Candidates must be local to Boulder or willing to relocate prior to starting.

Responsibilities

• Design and implement full‑stack applications using React (frontend) and Python (backend), with a database primary data store.
• Collaborate with scientists, laboratory operators, and business stakeholders to translate complex requirements into practical, production‑ready software solutions.
• Contribute to architectural decisions, system design reviews, and sprint planning within a collaborative software development team.
• Ensure software meets the highest standards of robustness, performance, and compliance, adhering to regulatory requirements (e.g., ISO 13485, IEC 62304).
• Follow software engineering best practices, including automated testing, CI/CD, and change management protocols.
• Integrate cloud computing solutions (e.g., AWS or GCP) for data analysis, storage, and deployment.
• Continuously improve existing codebases and internal development processes through refactoring and peer feedback.
• Engage in cross‑functional initiatives that span assay development, lab automation, and commercial software products.

Requirements

• 8+ years of professional full‑stack development experience, with significant time spent interacting with end users to develop and refine UX requirements.
• Strong proficiency in Python for backend development.
• Experience with PostgreSQL or similar relational databases.
• Familiarity with Docker and containerized environments; Kubernetes a plus.
• Exposure to cloud platforms such as AWS or Google Cloud Platform (GCP).
• Strong understanding of software development best practices including version control, testing, and code review.
• Excellent problem‑solving and communication skills.
• Enthusiasm for working in a mission‑driven team environment focused on patient impact.

Preferred Qualifications

• Experience in regulated software environments (ISO 13485, IEC 62304).
• Familiarity with bioinformatics workflows, clinical lab processes, or NGS data handling.
• Background in data visualization, scientific computing, or computational biology is a plus.

This role is hiring at an annual salary of $145,000 - $175,000 and is eligible for bonus and equity offerings. Foresight offers benefits including paid vacation, sick time, and parental leave (if applicable), alongside medical, dental, vision, life, disability coverage, flexible spending accounts, and a 401(k) with company match.

You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.