Senior Software Engineer
$150k - $185kStealth Startup
About Satomic Satomic’s mission is to close the gap from idea to molecule with faster navigation of chemical space. We are building an automated chemistry platform that integrates laboratory robotics, software, and AI to transform small‑molecule synthesis and drug discovery. Satomic has raised a $15M seed from investors including Riot Ventures, HOF Capital, and Compound VC. Our team includes alumni from leading large pharmas, small biotechs, and AI labs. About The Role This is a senior, hands‑on engineering role on the Development team. You’ll build, not manage, a team. Your focus will be on the core software platform at the center of Satomic’s chemistry operations: orchestration, internal tooling, and data systems that move a synthesis request from intake through execution to result. You’ll collaborate closely with the hiring manager, automation engineers, chemists, and ML/cheminformatics teams. The scope you own will grow as the platform evolves. A strong full‑stack engineer who owns problems end‑to‑end is required. You should design services and APIs, model data flows, and build interfaces for operators and scientists. You’ll drive architectural decisions that maintain system correctness as the platform expands, covering request orchestration, job scheduling, data capture, and internal web tools. We value engineers whose craft is not tied to a single language. Day‑to‑day, the role is primarily Python on the backend and TypeScript/React on the frontend, but you should be fluent across the stack and ready to pick up languages such as Rust, Go, or C++ when needed. Technologies And Systems You May Work With Python backend and TypeScript/React frontend, with flexibility to choose the right tool for the problem Relational databases and SQL (Postgres), data pipelines, and event‑driven systems that move data through the platform REST/gRPC APIs, message queues, and distributed systems design for experiment orchestration and platform control Cloud infrastructure (AWS, GCP, Azure), infrastructure‑as‑code, CI/CD, observability, and testing frameworks Integration with laboratory automation systems, ML/conversion models, and the cheminformatics search engine Expected Outcomes By Day 30 Develop a working understanding of the platform end‑to‑end, including the flow from intake through automated synthesis to result and identify software seams and pain points. Ship meaningful improvements or features into production, with tests and documentation. Engage with the existing roadmap, identify near‑term priorities, and flag dependencies and risks. By Day 90 Deliver at least one core service or system component that other teams build against, with a clear interface and solid understanding of failure modes. Establish or strengthen engineering practices around your work (testing, deployment, observability) to help the team move faster. See your work run under real production load as the platform begins shipping deliveries to customers. Partner with automation and chemistry teams to ensure structured, traceable data throughout the systems you work on. By Year 1 Become the primary owner of a major platform surface area and make architectural decisions independently. Keep those systems reliable as chemistry and automation requirements shift, evolving the architecture to stay robust. Raise the engineering bar on the team through the systems you build, code reviews, and practice establishment. By Year 5 Become a recognized technical leader within Satomic, shaping how the company builds software and mentoring strong engineers. Build core platform systems that scale across multiple generations of chemistry capability without accruing architectural debt. Make the software platform a durable competitive advantage in how Satomic runs chemistry at scale. What You Will Own Design, implement, and operate core platform services, APIs, and the orchestration layer behind Satomic’s "API to Atoms." The data model and data systems that capture, track, and expose platform activity, collaborating with data producers and consumers. Internal tooling that operators, chemists, and other engineers depend on for daily work. Engineering quality and operation of the systems you work on: testing, deployment, infrastructure‑as‑code, observability, production operations, and architectural decisions that maintain correctness. Proactive discovery of platform needs, working directly with chemistry and automation teams to surface new features and improvements. Technical judgment calls (build‑vs‑buy, complexity allocation, abstraction commitment) for your area of the platform, coordinated with the broader Development team on shared infrastructure. This Role Is A senior, hands‑on role building core software systems on Satomic’s platform. A full‑stack software engineering role (backend services, data, and frontend) where systems thinking, sound architecture, and the ability to own problems end‑to‑end matter. A role where you operate what you build, with infrastructure and on‑call shared across the team as the platform matures. This Role Is NOT A cheminformatics or chemistry‑domain engineering role. That work is owned elsewhere on the team; chemistry curiosity is welcome, but a chemistry background is not required. A pure ML or model‑training position. A single‑language specialist role. We want an engineer whose skill transfers across the stack and languages. A write‑the‑code‑and‑hand‑it‑off role. You operate what you build alongside the team, rather than delegating it for someone else to run. Qualifications 5+ years building and operating production software, with demonstrated ownership of end‑to‑end systems. Strong software engineering fundamentals: data modeling, API and service design, testing, and reliability reasoning. Strong Python (backend) and TypeScript/React (frontend) required, plus enthusiasm for learning new languages (Rust, Go, C++). Comfort reasoning about performance and making judgments about when performance matters. Track record of sound technical judgment and cross‑disciplinary collaboration. Solid knowledge of relational databases and SQL such as Postgres (schema design, query performance, data modeling). Experience designing and operating APIs and distributed systems (REST/gRPC, message queues) with sound service boundary judgment. Hands‑on experience with at least one major cloud platform (AWS, GCP, or Azure) and ownership of infrastructure‑as‑code, CI/CD, observability, and production operations. Bonus: experience building software at the intersection of the physical and digital world (lab automation, robotics, instrumentation, scientific data). Overview Of Satomic's Interview Process Phone screen (15‑30 minutes): introductory call with the hiring manager. Technical phone screen (45 minutes): in‑depth conversation with an engineer. Core Interviews (3 × 45 minutes): coordinated block of interviews with team members. Take‑home assignment: scoped engineering problem representative of Satomic work. Final round: technical review of the take‑home submission and presentation of prior work. Why Join Satomic Join a team tackling frontier challenges in chemistry and the biggest bottleneck in drug discovery, with an opportunity to shape the future of how molecules are discovered and made. Diversity & Inclusion We know there is a serious lack of diversity in our industry, and we are committed to driving change. Our culture is built on inclusion, humility, humanity, and ingenuity, values that guide how we work and approach the challenges of scaling science. Our mission carries responsibility; we care deeply about ensuring our platform is used for good. Building a diverse and thoughtful team gives us the best chance of delivering a platform that advances chemistry and drug discovery responsibly and with lasting positive impact on our world. Compensation Base salary: $150,000 – $185,000, along with meaningful equity ownership and competitive benefits. This role is in San Diego, CA. #J-18808-Ljbffr
- Description SAIC is hiring for a Senior Software Engineer who must be experienced in the full development life cycle using modern methodologies, such as Agile/Scrum and test-driven development. Ideal candidate will be experienced with complex coding in C++, CLI, C#, Java...Senior
$143k - $179k
We are seeking a Senior Software Engineer to join a new product engineering team being built in San Diego, developing software for providers in the sleep health diagnostics domain.This is a hands-on engineering role for someone who delivers high-quality software, raises...SeniorFull timeTemporary workWork experience placementFlexible hours$160k - $240k
.... Its products include Hivemind autonomy software, V-BAT and X-BAT aircraft, and Aechelon simulation... ...software integration, hardware, and test engineering to solve some of the hardest problems facing our customers.About the Job:As a Senior Software Engineer, you’ll build and own...SeniorFull timeTemporary workPart timeWorldwide$150k - $215k
...Vannevar, a defense technology company, is searching for an experienced Software Engineer in San Diego. The role involves owning technical roadmaps and deploying AI-enabled software products in secure environments. Candidates should have 7+ years in DevSecOps, full-stack...Senior- ...Senior Software EngineerInnovative Defense Technologies (IDT), a leading defense technology company, is seeking a Senior Software Engineer to be part of our Engineering team and based out of our Arlington, VA or Mount Laurel NJ location. The selected Software Engineer...SeniorWork at office
$162.7k - $199.3k
...businesses.We are seeking an experienced Senior Full Stack Developer to design, develop,... ...Skills5+ years of professional software development experienceExpert proficiency... ...CompetenciesBachelor's degree in Computer Science, Engineering, or equivalent practical...SeniorFull timeLocal area$175k - $200k
...possible in the realm of engagement. To learn more visit:POSITION SUMMARYSEPS is looking for a talented and motivated Senior Full Stack Software Engineer to join our team in building and enhancing internal applications that drive the Sony Engagement Platform. In this...SeniorFull timeTemporary workSummer workLocal areaImmediate startFlexible hours$122.5k - $183.7k
Company: Qualcomm Technologies, Inc. Job Area: Engineering Group, Engineering Group > Cellular Technologies Software General Summary: This individual independently plans, performs the moderately-defined responsibility for the designing, standardizing, implementing, verifying...SeniorFull time- ...As a Senior Software Engineer, you will lead small teams and contribute to project needs while executing a software development lifecycle plan. You will also implement and support Agile methodologies and provide active support for continuous improvement initiatives. Requirements...Senior
- ...Job Detail Job brief We are looking for a mid to senior level software engineer, with a primary focus in the Windows and .NET framework. You will re-factor and improve our existing applications as well as create applications from scratch and provide mentorship to...SeniorWork at officeFlexible hours
- ...Senior Software EngineerASEG Inc. seeks a Senior Software Engineer possessing subject matter expertise in Cloud architectures, operations and application deployment. Job OverviewExperience with Agile Development, notably Scaled Agile FrameworkDeveloping launch configurations...Senior
$103k
...taking advantage of increased operational complexity and risk in the industries we serve. That’s where you come in. Position: SENIOR SOFTWARE ENGINEER Salary: $ 103,000 per year Job Description: XPath 1.0 / XSLT Development, such as design and maintain complex XSLT...Senior- ...Lead a team to develop software to meet customer needs and ensure its continued high performance after it is launched. Work with team... ...Qualifications Bachelor's degree in Computer Science, Computer Software Engineering, Software Programming, or related field 10 years of experience...Senior
$100.5k - $153.25k
...in market-released products, demonstrating skills in an agile software environment. A customer-first approach is central to this role... ...software developer, as well as work alongside other software engineers to ensure a deep understanding of system requirements and capability...SeniorPermanent employmentContract workWork at officeImmediate start$146k - $155k
...We are a startup building complex, performance-critical software and hardware systems at the intersection of instrumentation, algorithms, and data. We are looking for a Senior Software Engineer who is equally comfortable writing low-level C/C++ for embedded targets and...SeniorFull time- ...Sr. Software Engineer PositionAt Globus Medical, we move with a sense of urgency to deliver innovations that improve the quality of life of patients with musculoskeletal disorders. Our team is inspired by the needs of these patients, and the surgeons and healthcare providers...Senior
- ...We combine architectural expertise with software, automation, and data systems to dramatically... ...it most.Our team blends architects, engineers, and product builders. We design real... ...great architecture scalable.The RoleAs a Senior Software Engineer, you'll help architect...SeniorFlexible hours
$124k - $187k
...Senior Software EngineerJob DescriptionCoStar Group (NASDAQ: CSGP) is a leading global provider of commercial and residential real estate... ...real estate.Role Description:We're seeking a Senior Software Engineer with strong C#/.NET experience, hands-on use of Claude for AI...SeniorFull timeWork from home$140k - $170k
...Senior Software Engineer The Mission: Do you want to build software that solves the world's most complex national security problems? At STR, we don't just write code; we bridge the gap between cutting-edge research and real-world mission success. You will join a multidisciplinary...SeniorFull timeLocal areaFlexible hoursNight shift- ...Senior Software EngineerSatomic's mission is to close the gap from idea to molecule with faster navigation of chemical space. We are building... ...gap from idea to molecule by building the chemistry search engine that lets our customers see, query, and reach into Satomic's...SeniorShift work
$124k - $187k
...brightest minds with the best resources available, we provide an invaluable edge in real estate. Role Description We’re seeking a Senior Software Engineer with strong C#/.NET experience, hands‑on use of Claude for AI‑assisted development, and proven experience building and...SeniorFull timeWork from home$162.7k - $199.3k
...Senior Full Stack DeveloperJLL empowers you to shape a brighter way.Our people at JLL... ...Technical Skills5+ years of professional software development experienceExpert proficiency... ...CompetenciesBachelor's degree in Computer Science, Engineering, or equivalent practical...SeniorDaily paid$160k - $220k
...Senior Software EngineerThis is a fully on-site role. Hybrid/remote work is not available at this time. We are unable to sponsor or take... ...at this time.RIVO is seeking an experienced Senior Software Engineer to help accelerate the evolution of our proprietary Loan Management...SeniorImmediate startRemote workWork visaWeekend work- ...candidate profiles across active roles and use resumes/profiles to understand which backgrounds may be a fit. THE ROLE As a Senior Software Engineer, you may work on projects that require strong execution, communication, analytical judgment, and the ability to move...Senior
- ...autonomous systems, mission command and control software, AI-enabled training and simulation, and... ..., Forward Slope, Systems Innovation Engineering, SoarTech, and Highbury Defense Group... ...and global perspective. Job Description Senior Full Stack Software Engineer (Level III)...SeniorFull timeTemporary workLocal areaRemote work
$143k - $179k
...Based in San Diego, our high-performing engineering team within Resmed’s Sleep Care Solutions... ...solving problems across the entire software development lifecycle – whether that’s investigating... ...We’re looking for a highly experienced Senior Software Engineer (L5) who can lead...SeniorContract workTemporary workWork experience placementWorldwideFlexible hours- ...digital capabilities across cloud, data, and software environments. Our teams tackle complex,... ...Architecture (NOA), working alongside engineers and operators to deliver resilient,... ...seeking a highly experienced and motivated Senior Software Engineer to contribute to the integration...SeniorFull time
$120k - $160k
...Location San Diego, CA, US Date Posted 2026-08-06 Category Software Subcategory SW Engineer Schedule Full-Time Shift Day Job Travel Yes - 10% of the... ...Work ORA_ON_SITE Description SAIC is looking for a Senior Software Engineer for a position located in San Diego, CA...SeniorFull timeRemote workShift work$140k - $200k
...doing seems to be working. We’re #1 in our category, and experiencing exponential growth. Overview We're looking for a Senior Software Engineer to join our Core Experiences Team. This team builds and maintains the foundational services and SDKs that power Speechify’...SeniorFull timeRemote work$160k - $180k
...combined capabilities, we provide deep expertise in Advanced Engineering; Digital Transformation; Electromagnetic Warfare;... ...the future. We are seeking a highly experienced and motivated Senior Software Engineer to contribute to the integration of AI capabilities...SeniorContract workLocal area
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Software Engineer. Be the first to apply!
- cybersecurity software engineer San Diego, CA
- graduate software engineer San Diego, CA
- software developer fintech San Diego, CA
- senior robotics software engineer San Diego, CA
- software engineer visa sponsorship San Diego, CA
- network software engineer San Diego, CA
- software engineer remote San Diego, CA
- part time software developer San Diego, CA
- part time software developer remote San Diego, CA
- software developer internship San Diego, CA


