Principal Scientist, Pharmacokinetics, Biologics

Principal Scientist position leading bioanalytical strategies for biologics in drug discovery. The role involves managing a team of scientists, developing ligand binding assays and mass spectrometry methods, and collaborating across immunology and oncology programs at the Boston research facility.

Responsibilities

• Lead bioanalytical strategies for drug discovery portfolio focused on biologics and modalities
• Manage team of laboratory scientists developing and executing ligand binding and mass spectrometry assays
• Serve as subject matter expert and project-team representative for DMPK activities in oncology and immunology
• Contribute to global DMPK strategy through collaboration with Discovery and Early Development teams across multiple sites

Requirements

• Ph.D. in biochemistry, chemistry, pharmacology, or related field with 6+ years relevant experience
• Demonstrated leadership of bioanalytical strategies for biologics including method development and data interpretation
• Experience analyzing pharmacokinetic, pharmacodynamic, and immunogenicity data for protein therapeutics
• Proven management experience mentoring multiple direct reports
• Strong communication, problem-solving, and cross-functional collaboration skills
• Technical expertise in ligand binding assays and mass spectrometry bioanalytical approaches