Senior Scientist, in vivo Pharmacology, Genetically Engineered Models - Comparative Medicine

Key Responsibilities Drive the design and generation of genetically engineered mouse models using advanced CRISPR-based genome engineering approaches. Develop and implement innovative technologies and approaches for animal genome engineering to advance the platform. Lead the genetic and molecular characterization of engineered models to ensure scientific rigor and translational relevance. Ensure compliance with institutional and regulatory protocols, policies, and guidelines governing animal research. Evaluate emerging technologies and apply new insights to strengthen in vivo disease modeling. Collaborate with the global GEMs team and external partners to expand model generation capabilities and meet program priorities. Essential Requirements Ph.D. in a natural or life science discipline (preferably molecular biology, genetics, or developmental biology) with 2+ years of relevant hands‑on experience in a matrixed environment; or MS with 8+ years of directly related experience (preferably in industry). Demonstrated expertise in genetically engineered animal model generation, including proficiency in PCR and next‑generation sequencing for genetic characterization. Strong attention to detail and working knowledge of animal use protocols, welfare compliance requirements, and regulatory standards; experience documenting studies in paper and electronic laboratory records. Desirable Requirements Proven ability to lead and influence programs or platform initiatives in a highly collaborative, matrixed environment. Working knowledge of advanced mouse model characterization (transcriptomics, proteomics, metabolomics). Experience managing 1–2 direct reports and supporting talent development and team culture. #J-18808-Ljbffr Scorpion Therapeutics