Staff Scientist - Hematologic Malignancies and Cancer Immunotherapy

Join the forefront of groundbreaking research at City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. The Zhang and Marcucci Laboratories at City of Hope are seeking a highly motivated Staff Scientist to join our research program in hematologic malignancies and cancer immunotherapy. Our research focuses on leukemia stem cells, the tumor microenvironment, CAR T-cell therapy, bispecific T-cell engagers, and microRNA biology, with the goal of developing novel therapies for leukemia and myeloproliferative neoplasms. The successful candidate will lead independent and collaborative projects and contribute to high-impact publications and translational research. As a successful candidate, you will: Perform cell culture, lentiviral transduction, and molecular biology experiments. Conduct multi-color flow cytometry and data analysis. Perform in vivo studies using mouse models, including oral gavage, intravenous, and intraperitoneal injections. Analyze data, prepare manuscripts and grant applications, and present research findings. Your qualifications should include: Ph.D. in Immunology, Cancer Biology, Hematology, Molecular Biology, or a related field. Hands-on experience with cell culture, lentiviral transduction, flow cytometry, molecular biology (e.g., CRISPR/Cas9, qPCR, Western blotting), and mouse studies. Excellent communication, organizational, and scientific writing skills. Preferred qualifications: Experience with CAR T-cell engineering, patient-derived xenograft (PDX) models, or cancer immunotherapy. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. #J-18808-Ljbffr aa067