Chief of Staff, CEO
$300 per monthEdison Scientific
About Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biology, physics, chemistry, and AI. Role This is Chief of Staff to Sam Rodriques, Edison Scientific's co-founder and CEO. This role is one of the highest-leverage seats in the company: you will sit next to Sam, with a front-row view of how Edison is built and how we are accelerating science. That means running Sam's most critical meetings, owning the projects that fall between teams, and keeping the machine around the CEO tight and fast. You will be the person who makes sure the most important work at Edison actually moves. While at times the job may seem mundane, it means giving you access to—and oftentimes a voice in—conversations and people far beyond what your tenure anywhere else would allow. Two things matter more than anything else. First, you have to be genuinely bought into Sam and where he is taking Edison. You will carry his thinking into rooms, sometimes to people who disagree. That only works if you believe it. Second, you must have a passion and genuine curiosity for science. This is an absolute-must. We think of this as a roughly 18-month commitment, and later a launchpad into another senior role at Edison or somewhere else. The role is in our San Francisco office in Dogpatch five days per week. Responsibilities Run the operating cadence — board prep, executive staff, planning, and KPI reviews — so decisions get made and priorities stay clear across the company. Drive CEO communications: Partner closely on everything CEO-facing. Internal: all-hands, company emails, employee recognition. External: prep for interviews, talks, and speeches. Special projects and strategic support: Take on some of the company's most important cross-functional work that either has no clear owner or where the current owner isn't getting the result Sam needs. Own it end-to-end and drive it to completion. Design and master the support engine around Sam: Make sure everything around the CEO runs smoothly, and step in to unblock when they do not. Requirements 3+ years of strategic business experience, preferably at a high-growth tech startup, finance or consulting. High-agency and low-ego. You figure out what's needed and just do it. Exceptional organization and follow-through. Nothing falls through the cracks. Strong written and verbal communication. You can write in Sam's voice and speak clearly to anyone from a scientist to a customer to an investor. Comfort in high uncertainty. You get things done without a playbook and without close oversight. AI fluency and enthusiasm — you actively use AI to create leverage in your work and are excited about where it's headed (formal AI experience not required). Willingness to commit ~18 months in this role. Experience in a demanding, fast-moving environment (high-growth startup, consulting, finance, operating roles, or similar). Bonus points for Bachelor’s in biology or other scientific fields. Prior founder, or early-stage operating experience at an AI company. Experience inside a company that scaled fast. Why join us? Competitive salary and equity Full healthcare coverage — we pay 100% of premiums for you and your dependents Support for growing families, including a yearly new parent stipend and fertility coverage through Carrot Mental health support through Rula, our in-network therapist and psychiatrist network with fast availability 12 weeks of paid parental leave for maternity, paternity, and adoption Pet care support with a yearly employer-funded stipend for your animal companions Commuter benefits so you can pay for transit and parking with pre-tax dollars 401(k) company matching $300 health and wellness benefit quarterly Lunch is on us every day you're in the office, and dinner is on us when you're working late Regular team offsites and company events A fast-moving, mission-driven culture where smart people do their best work and actually enjoy doing it Edison Scientific is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected characteristic under applicable law.
- ...Coinbase, and Palantir, among others Build a massive, fast-growing business with billions in revenue The Role The Chief of Staff to the CEO is Garrett Lord's closest execution partner - the person who helps him get things done at extraordinary speed across...SuggestedFull timeFreelanceInternshipWork at officeRemote workFlexible hours
- ...caliber team turning the art of sales into a scalable science. About the Role We're looking for a Chief of Staff who will operate as a true extension of the CEO. This is a rare opportunity to work directly alongside the CEO and gain an inside view into how a high-...Suggested
- Formic, a company redefining American manufacturing, is hiring a Chief of Staff to support the CEO in driving high-impact strategies and initiatives. This role requires strong judgment, ownership, and operational efficiency. Responsibilities include maintaining CEO focus...Suggested
- A healthcare technology firm in San Francisco seeks a Growth Chief of Staff to work directly with the CEO, driving high-impact initiatives and shaping strategic growth. The ideal candidate will bring consulting-level expertise from top firms and a strong MBA background...Suggested
- ...leader. This is a rare opportunity to join a company at an inflection point and help shape what it becomes. Role Overview The Chief of Staff to the CEO is a strategic operator role, not an administrative one. You will serve as the CEO’s force multiplier: owning high-stakes...Suggested
- ...someone else sold back. So that's what we make: a liquid market for GPU offtake. About TheRole SF Compute is seeking a Chief of Staff to the CEO to serve as a strategic partner and force multiplier to the CEO. This role combines strategy, operations, and execution, working...Long term contractFull timeContract workFixed term contractWork at officeLocal areaVisa sponsorshipShift work
- A pioneering AI banking startup is seeking a strategic partner to work directly with the CEO in managing critical projects during scaling. You'll coordinate cross-functional teams, drive operational excellence, and address complex challenges in a high-growth environment...
$132k - $178k
A fast-growing financial technology company is looking for a Chief of Staff to the CEO in San Francisco. This role involves a mix of strategic and tactical responsibilities, combining project management with operational execution. Candidates should have 4-6 years of experience...- Sapiom is seeking a Chief of Staff to the CEO in San Francisco, California. This role is at the heart of the company and entails architecting the operational backbone to ensure scalability. The candidate will translate founder intent into smooth execution, aligning key...
- A financial services startup in San Francisco is searching for a Chief of Staff. This part-time role involves collaborating with the CEO on various initiatives, covering marketing, compliance, and customer support. Candidates should be resourceful and able to work independently...Full timePart time
$200k - $250k
Ema is seeking a Chief of Staff to the CEO to play a pivotal role within the team. The ideal candidate will have significant experience in strategic leadership and senior positions at high-growth companies, ensuring alignment across various functions while directly supporting...$150k - $235k
What you will do You will work extremely closely with, and act as a force multiplier to the CEO: taking on our hardest, most complex, most interdisciplinary problems… to make sure the company runs well and WINS! You should expect the role to progress as follows: First...Full timeWork at officeRelocation packageFlexible hoursWeekend work$227k - $289k
...Included Health is hiring a Chief of Staff to the CEO who is equal parts strategic partner and operator. You’ll run the Office of the CEO and act as a force multiplier—translating strategy into sequenced execution across the organization. You’ll architect and enforce our...Full timeWork at officeLocal areaRemote workWork from homeHome office- ...Candidates must be able to reliably commute to the office Monday–Friday. What You'll Do: Serve as a trusted thought partner to the CEO, working side‑by‑side on strategic priorities, planning cycles, and special projects that drive Inkitt’s growth. Oversee cross‑...Work at officeMonday to Friday
- ...investors, and count global enterprises and Fortune 500 brands among their customers. The Opportunity As Chief of Staff, you will work directly alongside the CEO of a fast-growing AI infrastructure startup, operating as a high-caliber generalist across strategy,...Shift work
- ...Chief Of Staff We're looking for a Chief Of Staff who is highly driven, organized, comfortable with ambiguity, and excited to join us in... ...build and scale the company. You'll work directly with the CEO and set the cadence for how the company operates. You'll own end...
- ...Tens of millions of transactions today, billions ahead. THE ROLE We're looking for a swiss army knife / Chief of Staff to work directly with our CEO at Sphere . You'll be an extension of Nick, helping him across GTM, Ops, Finance, Tax and more. It will be intense...Work at officeWeekend work
$110k - $160k
...work with teams across the United States to help them hire. Chief of Staff Location: San Francisco, CA (On-site) Company Stage of... ...at a critical growth stage and work directly alongside the CEO across operations, GTM, strategy, hiring, and execution. What...Work at officeRemote workVisa sponsorship- ...This is one of the most important roles within the company. As Chief of Staff, you will work closely with the CEO across many of the most important business functions - strategy, recruiting, operations, fundraising, culture, and more. We're willing to take 6 months to...RelocationVisa sponsorship
- ...Chief Of Staff Opportunity We're automating compliance for banks and fintechs with AI agents that work like human analysts. We're looking for a Chief Of Staff to work directly with the CEO — someone who can operate across every function of the business, make the founder...Temporary workWork at officeRelocation packageShift work
- ...We are looking for a Chief of Staff to join our team in San Francisco. In this role, you will work directly with the CEO on initiatives across product, marketing, and operations. This is a part-time role, with the potential to transition into a full-time role...Full timePart time
$115k - $150k
...Chief Of Staff Kada Recruiting is partnering with a fast-growing, venture-backed AI startup to find a dynamic Chief of Staff to join their... .... This is an exciting opportunity to work directly with the CEO and leadership team at a company that's reshaping how developers...Work at officeRemote work- ...Chief of Staff San Francisco, California Full Time As Chief of Staff, you'll partner closely with the leadership team to drive... ...Strategic Leadership and Execution Collaborate with the CEO and CTO to define and execute the company's strategic vision....Full timeContract work
- ...Arcade Office Of The CEO, Chief Of Staff Arcade is building the world's first AI physical product creation platform, where imagination becomes reality. Our platform lets anyone design, purchase, and sell custom, manufacturable products using natural language and generative...Work at officeImmediate start
- ...humans once had to do. This is your chance to be the CEO's right hand during our most critical scaling phase. You'll be... ...Experience managing internal operations, team coordination, or chief of staff responsibilities at high-growth companies ~ Strong...
$180.92k
...Summit Public Schools Current job opportunities are posted here as they become available. Reports to: CEO Location: Bay Area Preferred Position Overview The Chief of Staff & Strategy is a senior leader responsible for ensuring Summit operates as a strategically aligned,...- Chief of Staff & Head of Strategic Partnerships At Snappr , we're changing the world by making amazing photography accessible to everyone.... ...the heart of the organization, working as the link between our CEO (ex-McKinsey) and the company’s department heads. You will play...
$200k - $250k
...what Agentic AI can do in production — we ship real systems that run real business processes at scale. Role Overview As Chief of Staff to the CEO, you will be the strategic nerve center of the entire company — a true force‑multiplier to Surojit Chatterjee (ex CPO Coinbase...Work at officeWorldwideRelocation$120k - $160k
...4 · ~8 people · Industry: Consumer Tech / AI The Role Be the CEO's right hand and force multiplier. Take strategic projects and... ...Wants 9-5 or strict work-life-balance role Pure manager / "Chief of Staff" in the corporate sense (delegating, scheduling, no IC work)....Full timeWork at officeRemote workVisa sponsorshipShift workWeekend workDay shift- ...Integrate with physical channels (outdoor ads, CTV, retail stores, events) Job Overview Flam is hiring a Chief of Staff to act as the operational quarterback for the CEO and broader leadership team. You’ll work directly with the CEO and closely support Flam’s Head of...Shift work
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Chief of Staff, CEO. Be the first to apply!
- chief of staff to the ceo San Francisco, CA
- chief of staff San Francisco, CA
- chief of staff remote San Francisco, CA
- change management executive San Francisco, CA
- executive work from home San Francisco, CA
- technical executive San Francisco, CA
- managing director financial services San Francisco, CA
- executive team lead asset protection San Francisco, CA
- executive director for marketing & public relations San Francisco, CA
- executive program manager San Francisco, CA

