Research Scientist

100% on-site Position Summary The CV Translational Early Development group within the Immunology and Cardiovascular Thematic Research Center (ICV-TRC) at Client seeks to understand hypothesis-driven disease pathophysiology to enable patient selection and stratification in clinical trials. The team is highly focused on identifying circulating biomarkers of disease severity to enhance patient stratification and aid the testing of cardiovascular early discovery preclinical candidates. We are seeking a talented and highly motivated research scientist interested in a fast-paced scientific environment. The individual will develop critical assays to evaluate target engagement and pharmacodynamics of our new drugs in patients and provide a better understanding of target biology in disease. Primary responsibilities would include cell culture and conducting cell-based assays. The ideal candidate would be able to work independently, demonstrate flexibility and be willing to work as a member of a large cross-functional team. Key Responsibilities Actively contribute to translational projects which are aligned with CV & FIB Translational Research objectives. Responsibilities may include laboratory work, literature/data review, and/or computational analyses. Work independently in cell culture (iPSC-CMs experience is a plus) and develop cell-based assays as needed. Qualifications & Experience BS or MS in relevant scientific discipline (biology, biochemistry, cell biology, etc.) with 2+ years of relevant experience. Experience with cell culture (cardiomyocytes is preferred) and cell-based assay development. Knowledge of cardiovascular biology and heart failure pathophysiology. Experience with wet lab experimentation, analysis & interpretation of results is required. Understanding of drug discovery process is preferred. Interpersonal and collaboration skills, including the willingness and ability to foster working relationships with a range of stakeholders. #J-18808-Ljbffr