Protein Biochemist

Associate Scientist (Contract) – Protein Sciences

Position Summary

We are seeking a highly motivated Associate Scientist (Contract) to support our Protein Sciences team. This individual will contribute as a hands-on laboratory scientist, executing protein production, purification, and analytical workflows that support multiple CAR-T and cell therapy programs.

This is a 100% bench-focused, individual contributor role. The successful candidate will work closely with scientists across Protein Science and Research to generate high-quality data and reagents, while contributing to efficient laboratory operations and experimental execution.

Key Responsibilities

Protein Production & Purification

· Execute recombinant protein expression and purification workflows across multiple expression systems (e.g., mammalian cell culture, transient transfections)

· Perform protein purification using AKTA chromatography systems (affinity, SEC, ion exchange)

· Maintain cell cultures and support transfection workflows

Analytical Characterization

· Perform biochemical and biophysical characterization of proteins and antibodies, including:

o SDS-PAGE and Western blot

o UPLC/HPLC-based purity assessment

o Binding assays (e.g., Octet/BLI)

· Document and summarize experimental data clearly to support team decision-making

Protein Modification & Assay Support

· Perform antibody and protein conjugation workflows with appropriate analytical follow-up

· Prepare reagents and materials to support downstream functional assays (e.g., flow cytometry or cell-based assays in collaboration with Cell Biology partners)

Lab Operations & Execution

· Maintain organized lab practices, including reagents, consumables, and shared equipment

· Ensure accurate experimental documentation in electronic lab notebooks and LIMS

· Follow established SOPs and contribute to maintaining reproducibility and data quality standards

Collaboration

· Work closely with cross-functional partners to execute experiments aligned with defined protocols and timelines

· Communicate experimental progress and results effectively to project teams

Basic Qualifications

· Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, Protein Science, or related field

· 2–4+ years of relevant hands-on laboratory experience in academic or industry settings

Preferred Qualifications

· Experience with recombinant protein expression and purification workflows

· Hands-on experience with AKTA systems and chromatography methods

· Familiarity with protein characterization techniques (SDS-PAGE, HPLC, BLI/Octet, etc.)

· Experience with mammalian cell culture and transfections

· Strong attention to detail and commitment to high-quality data generation and documentation

· Ability to follow protocols, troubleshoot at the experiment level, and work effectively in a fast-paced lab environment

Key Characteristics for Success in This Role

· Strong hands-on bench execution skills

· High level of organization and reproducibility

· Ability to independently execute experiments with appropriate controls

· Collaborative mindset and willingness to support team priorities