Sr. Project Manager

Sr. Project Manager

South San Francisco, California, United States

A career here is life-enhancing.

At Syner-G, we enable our people to build careers that impact positively on their quality of life. Through our expertise, insight, consulting and management skills, we accelerate breakthrough science and delivery of life-enhancing therapies to more patients. We work across a diverse range of clients and projects, supporting many organizations from the most critical phases of the drug discovery and approval process through to commercialization. It is meaningful, varied and thought-provoking work with a strategic emphasis, a solutions-driven approach and significant, real-world outcomes, from science to delivery/success. To learn more about who we are and what drives us, watch our company video here.

Underpinning this mission is a culture that aligns perfectly with what we want to achieve. We enable our people to grow, we support them in their learning and we reward them in so many different ways. In return, they play an instrumental role in maintaining our reputation across the globe as a strategic biopharma product development and delivery partner.

Syner-G was recently honored with BioSpace's prestigious "Best Places to Work" 2026 award, for the third consecutive year, along with many other award-winning programs to make a career here truly life-enhancing. These recognitions are a testament to our commitment to fostering a positive and engaging work environment for our employees, with a particular emphasis on culture, career growth and development opportunities, financial rewards, leadership and innovation.

At Syner-G, we recognize that our team members are our most valuable asset. Join us in shaping the future, where your talents are valued, and your contributions make a meaningful impact.

POSITION OVERVIEW:

Syner-G is seeking a Sr. Project Manager to lead and manage complex construction and engineering projects from initial planning through commissioning and closeout. This role is responsible for ensuring projects are delivered on schedule, within budget, and in alignment with quality, safety, and regulatory expectations. The Sr. Project Manager will serve as a primary point of coordination between clients, contractors, engineering teams, and internal stakeholders, providing leadership, technical oversight, and strategic guidance throughout the project lifecycle.

WORK LOCATION:

Travel to client sites may be required up to 100%, based on project demands and client expectations.

KEY RESPONSIBILITIES:

• Keep the Project Director informed of project risks, issues, and progress, and present recommended solutions or mitigation strategies.
• Review technical submissions from Architectural and Engineering (A&E) firms, including MEP drawings, structural drawings, and construction specifications.
• Respond to and manage construction communications such as RFIs, submittals, and technical clarifications.
• Assist with and oversee preparation of job start-up and close-out checklists.
• Read, interpret, and manage project plans, specifications, contracts, subcontracts, purchase orders, correspondence, shop drawings, and all other project-related documents.
• Maintain a complete and accurate set of as-built project documents.
• Manage Transfer of Care and Custody (TOCC) to facilities operations, ensuring thorough documentation and smooth transition from construction to maintenance mode.
• Utilize project and construction management software such as ProCore, E-Builder, or Prolog.
• Act as the owner's representative on capital projects, ensuring alignment with client expectations and project goals.
• Use Microsoft Project to develop, maintain, and track project schedules.
• Lead daily planning meetings, document observations, and ensure alignment across project teams.
• Walk construction sites regularly to identify field issues, verify progress, and present solutions.
• Prepare daily reports, photo documentation, and progress measurements.
• Review construction site safety documents such as work permits, task plans, and job hazard analyses, and collaborate with the client's EHS team to ensure compliance.
• Mobilize, coordinate, and supervise contractors including general contractors, construction managers, mechanical, electrical, and specialty trades.
• Oversee project execution in operating facilities, ensuring minimal disruption to ongoing operations.
• Support start-up, commissioning, and handover of building systems including HVAC, emergency power, UPS systems, lab gases, RODI water, boilers, and steam generators.
• Create stakeholder engagement, communication, and executive engagement strategies across leadership and project teams.
• Develop executive presentations, strategic communications, and compelling narratives that translate complex information into clear, actionable insights for leadership decision-making.
• Establish portfolio reporting, KPIs, performance metrics, and management routines.
• Drive organizational effectiveness, change management, risk management, and continuous improvement initiatives.

QUALIFICATIONS AND REQUIREMENTS:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements below represent the education, experience, skills, knowledge, and abilities required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Education:

• Bachelor's degree in Mechanical, Chemical, Electrical Engineering, or a related field preferred.
• PMP certification is a plus.

Technical Experience :

• 8–14 years of experience as a project engineer or project manager, preferably in the petrochemical, chemical, refining, or related industrial sectors.
• Experience managing major capital projects from design through construction, commissioning, and handover.
• Experience supervising and coordinating contractors across multiple disciplines (GC, CM, mechanical, electrical, etc.).
• Experience executing projects within active operating facilities.
• Experience with commissioning and turnover of building systems such as HVAC, emergency power, UPS, lab gases, RODI water, boilers, and steam systems.
• Experience conducting site walks, identifying field issues, and developing solutions.
• Experience leading daily planning meetings and documenting project activities.
• Experience preparing daily reports, photo documentation, and progress tracking.
• Experience reviewing safety documentation and collaborating with EHS teams.

Knowledge, Skills, and Abilities:

• Strong communication skills with the ability to interface effectively with client stakeholders, managers, contractors, and subcontractors.
• Proficiency with Microsoft Project and familiarity with construction management software.
• Detail-oriented with strong analytical, organizational, and problem-solving skills. Ability to manage multiple priorities in a fast-paced environment.

ESSENTIAL FUNCTIONS:

Physical Demands :

The physical demands described here are representative of the requirements that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to use a computer keyboard and mouse; reach with hands and arms; talk and listen. The employee is frequently required to walk and sit, as well as to lift and carry objects such as books and files weighing up to 25 pounds. The employee is occasionally required to stand, stoop, or kneel. Specific vision abilities required by this position include close vision and the ability to adjust focus.

Work Environment :

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job, including moderate noise level, an indoor temperate environment, and light levels that are bright and conducive to minimal eye strain, typical for an office environment.

TOTAL REWARDS PROGRAM :

We define total rewards as compensation, benefits, remote work/flexibility, development, recognition, and our culture with programs that support each of our reward pillars. This includes a market competitive base salary and annual incentive plan, robust benefit offerings, and ongoing recognition and career development opportunities. Employees also enjoy our generous flexible paid time off program, company-paid holidays, flexible working hours, and fully remote work options for most positions and the ability to work "almost anywhere." However, if a physical work location is more for you, we have office locations in Greater Boston; San Diego, CA; Boulder, CO; and India.

COMPENSATION :

The expected salary range for this position is $150,000 to $170,000 yearly. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.

Currently, Syner-G is unable to sponsor or take over sponsorship of an employment Visa at this time.

LEGAL STATEMENT: Syner-G is proud to be an Equal Employment Opportunity and Affirmative Action employers. All employment decisions, including the recruiting, hiring, placement, training availability, promotion,