Research Technician II

Research Technician

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career.

CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.

A Brief Overview

This entry-level research technical role participates in a planned research projects by performing research protocols, experimental procedures and other laboratory tasks under direct supervision. May occasionally exercise minimal discretion and judgment in execution and interpretation of experiments, and of data derived.

Dr Tasian's translational laboratory in the Division of Oncology and Center for Childhood Cancer Research focuses upon the development of new treatments for high-risk childhood leukemias with an emphasis upon small molecule inhibitor therapies and cellular (CAR T cell) immunotherapies. Dr Tasian is seeking a motivated, dynamic, and hard-working Research Technician to join her laboratory to assist with preclinical animal model studies and with correlative biology studies for childhood leukemia clinical trials using primary patient samples.

What You Will Do

• Ability to process patient leukemia specimens following appropriate training, handle confidential patient-related materials, and maintain a protected database of confidential patient-related information from clinical trials.
• Ability to perform specialized animal studies (immunocompromised mice) for human leukemia xenotransplantation, preclinical drug or cell therapy treatment, disease monitoring, treatment efficacy analyses, and pharmacodynamic monitoring. Specific animal skills will be mastered after training and include retro-orbital venous bleeding, tail vein injections, intraperitoneal injections, oral gavage, bioluminescent imaging, and tissue processing.
• Ability to learn specialized flow cytometry analysis of mouse and human samples and to use flow cytometry data analysis and graphing software.
• Ability to troubleshoot and plan experiments with appropriate Principal Investigator and post-doctoral fellow oversight. Ideally, the candidate will contribute to writing of scientific manuscripts and to figure preparation; co-authorship will be commensurate with level of project involvement and manuscript contributions.
• Ability to handle multiple, time-dependent tasks efficiently and conscientiously and to conduct oneself with professionalism and maturity. Being a good team player is a must for our laboratory culture, and a good sense of humor is also quite welcome!
• Excellent organizational and analytical skills.
• Ability to use computers, email, Word, and PowerPoint software and to learn other programs needed for data presentation and figure preparation (eg, Prism).
• Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee
• Performs research procedures on experimental samples as directed
• Records and checks experiments/ results for completeness and accuracy
• Performs calculations and maintains appropriate log and lab notebooks
• Performs tasks that require familiarity with fundamental techniques and lab equipment
• May assist with planning specific research protocols and procedures
• Maintains office, lab area, solutions, reagents, supplies and equipment, disposes of specimens, media and other materials (using appropriate procedures)
• Assists in care and maintenance of lab equipment
• May coordinate schedules of tests and procedures
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
• Records results, organizes data and maintains lab notebook in an organized manner
• Compiles and helps analyze data, prepares charts, graphs, and results of studies as directed
• Conducts literary searches as directed

Education Qualifications

• High School Diploma / GED - Required
• Associate's Degree - Preferred
• Bachelor's Degree - Preferred

Experience Qualifications

• At least one (1) year of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Required
• At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Preferred

Skills and Abilities

• Intermediate understanding of lab procedures, protocols, and equipment.
• Basic exposure to lab specific experiments / techniques and scientific analysis
• Excellent verbal and written communications skills
• Excellent organizational skills
• Solid critical thinking / problem-solving skills
• Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine.

SALARY RANGE:

$43,900.00 - $54,800.00 Annually

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly. At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.