Senior Bioinformatics Programmer

NYU Grossman School of Medicine is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health, the Grossman School of Medicine at its core is committed to improving the human condition through medical education, scientific research, and direct patient care. At NYU Langone Health, equity and inclusion are fundamental values. We strive to be a place where our exceptionally talented faculty, staff, and students of all identities can thrive. Position Summary We have an exciting opportunity to join our team as a Senior Bioinformatics Programmer working in a Molecular Diagnostics environment. This position is an onsite role for a minimum of 6 months with the potential for a hybrid role after that based on performance. Ability to be onsite 3 to 5 days a week is a must (possibility of full remote work is currently not available). Job Responsibilities Enhance or develop new automated workflows/pipelines within a Nextflow environment for bioinformatic tools utilizing next generation sequencing data in clinical diagnostic assays Use existing bioinformatics pipelines to analyze the molecular patient data generated in the clinical lab Oversee systems support for existing bioinformatics pipelines and develop new pipelines to support new molecular assays Support the team in its common clinical genomics and precision medicine goals Perform quality control of the generated sequencing data and develop solutions to enhance future performance Perform different types of data analysis relating to the genomics‑based approaches utilized by the lab, in an independent fashion Develop new methods for multi‑omics data analysis and integration Work with bioinformatics scientists and clinical pathologists to analyze and interpret patient NGS results for better potential treatment options Work with lab users to analyze biomedical data and address clinical needs using bioinformatics techniques and tools Work with MCIIT and HPC team to provide current and future solutions for server, storage and other requirements Preferred Qualifications Expert in creating customized sequencing analysis pipelines, in applications for data analysis, and executing standard bioinformatics pipelines (relevant examples in a GitHub repository) Basic knowledge and understanding of software engineering concepts Knowledge of algorithms, data structures, machine learning Prior experience working in CLIA environment is a plus Experience in variant calling benchmarking and clinical validation analysis (e.g. concordance, limit of detection, assay reproducibility) Experience with running workflows on public cloud (GCP / AWS) Experience with developing and querying databases using SQL queries Experience with web‑development (HTML, CSS, JavaScript, TypeScript and related) Minimum Qualifications To qualify you must have a M.Sc. plus a minimum of 3 years' experience in Bioinformatics, Computer Science, Programming, Software Development, or related field Previous experience with NGS data and associated bioinformatics tools Experience in Unix/Linux systems including high‑performance computing environments Strong programming skills in Python, R, shell scripting Proficiency in Nextflow, Django, Docker and Singularity containers Work experience and algorithm understanding of standard software tools used to generate and manipulate FASTQ, BAM, VCF files including but not limited to BWA, GATK, Picard, samtools, bcftools Knowledge in the analysis of SNV, Indel, CNV and structural variants for both somatic and germline disease, additional understanding of variant annotation Familiarity with various NGS QC principles Knowledge of biology, cancer genomics or an understanding of key and complex biological concepts Detail‑oriented, well‑organized and an interest in clinical sequencing and disease‑related or cancer genomics Ability to work independently (recommend new software or bioinformatic tools, find relevant papers, assess methods, implement methods, and apply them to datasets to reproduce results) Team oriented with excellent written and verbal communication skills Ability to function in a multidisciplinary team including MDs and PhDs Qualified candidates must be able to effectively communicate with all levels of the organization. NYU Grossman School of Medicine provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents. At NYU Langone Health, we are committed to supporting our workforce and their loved ones with a comprehensive benefits and wellness package. Our offerings provide a robust support system for any stage of life, whether it's developing your career, starting a family, or saving for retirement. The support employees receive goes beyond a standard benefit offering, where employees have access to financial security benefits, a generous time‑off program and employee resources groups for peer support. Additionally, all employees have access to our holistic employee wellness program, which focuses on seven key areas of well‑being: physical, mental, nutritional, sleep, social, financial, and preventive care. The benefits and wellness package is designed to allow you to focus on what truly matters. Join us and experience the extensive resources and services designed to enhance your overall quality of life for you and your family. NYU Grossman School of Medicine is an equal opportunity employer and committed to inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration. We require applications to be completed online. View Know Your Rights: Workplace discrimination is illegal. NYU Langone Health provides a salary range to comply with the New York state Law on Salary Transparency in Job Advertisements. The salary range for the role is $84,577.92 - $105,039.78 Annually. Actual salaries depend on a variety of factors, including experience, specialty, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits. #J-18808-Ljbffr NYU Grossman School of Medicine