Project Manager II - Veeva Vault Clinical (CTMS & eTMF)

Project Manager II – Veeva Vault Clinical (CTMS & eTMF)

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.

Discover what your 25,000 future colleagues already know:

Why Syneos Health
• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life. 
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. 

Job Responsibilities

Project Manager II – Veeva Vault Clinical (CTMS & eTMF)

Sponsor-Dedicated | Remote (U.S.)

If you’re a Veeva Vault expert who thrives at the intersection of clinical operations, systems, and governance, this is a high-visibility opportunity to take ownership of CTMS and eTMF operations post-go-live within a leading sponsor environment.

This role sits within the Clinical Trial Capabilities Business Support Model, blending hands-on operational ownership (50%) with strategic program support (50%)—ideal for someone who understands both the technical backbone of Vault Clinical and the real-world execution of clinical trials.

Why This Opportunity

• Direct impact on enterprise-wide CTMS & eTMF operations

• High exposure to Clinical Operations, R&D Quality, and IT leadership

• Ownership of post-go-live system governance and optimization

• A chance to operate as a true SME and trusted advisor in a complex, matrixed environment

What You’ll Do

Operational Ownership & Centralized Support

• Serve as the primary business-facing owner of Vault Clinical in production

• Provide centralized support and guidance to Clinical Operations and key users

• Act as the escalation point for system and process issues, driving resolution across cross-functional teams

Governance, Compliance & Inspection Readiness

• Ensure inspection-ready documentation with strong change control and configuration management

• Support and maintain data governance processes

• Manage and triage change control intake from a business perspective

Change, Release & Lifecycle Management

• Partner with Clinical Systems and IT on impact assessments and controlled changes

• Ensure alignment between system functionality and business processes

• Lead release readiness activities (training, communications, SOP updates)

Stakeholder Partnership & Enablement

• Act as a trusted advisor and SME to stakeholders across Clinical, Quality, and Systems

• Develop and deliver training, job aids, and operational guidance

• Coordinate with vendors and FSP partners, ensuring clear accountability and oversight

Program Support

• Support Program Leads and Business Process Owners (BPOs) through workshops and execution of key initiatives

• Contribute to continuous improvement and optimization efforts across Vault Clinical

What You Bring (Required)

• 5+ years supporting GxP-regulated clinical systems, with deep expertise in CTMS and/or eTMF

• Veeva Vault SME — strong understanding of both front-end usage and back-end configuration

• Proven experience in post-go-live system support, governance, and centralized operating models

• Strong (3+ years) project management background in clinical research, including:

  • Study oversight, timelines, and deliverables

  • Vendor and budget management

  • Issue identification and resolution across trial operations

• Experience integrating Veeva Vault within clinical programs

• Demonstrated ability to influence cross-functional stakeholders in a matrixed environment

Key Strengths

• Deep understanding of GxP compliance, risk identification, and data integrity

• Ability to translate complex system challenges into practical solutions

• Clear grasp of system governance vs. operational execution

• Confident decision-making with appropriate risk escalation

This is not a passive support role—this is a hands-on, strategic ownership position for someone who knows Vault Clinical inside and out and wants to shape how it operates at scale.

If you’re ready to step into a high-impact SME role within a sponsor-dedicated model, let’s connect!

At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.  Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

$95,000.00 - $175,700.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive.  The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description.  The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above.   Further, nothing contained herein should be construed to create an employment contract.  Occasionally, required skills/experiences for jobs are expressed in brief terms.  Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees.  The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Summary

Roles within Clinical Project Management job family at the M23 level are responsible for planning, directing, creating, and communicating clinical study timelines. These roles gather input from cross-functional teams to create plans that help the team produce deliverables on schedule. They ensure consistency of clinical study and processes across clinical trials, overseeing and resolving operational aspects of clinical trials in conjunction with project teams and in accordance with standard operating procedures (SOP), good clinical practice (GCP), and specific country regulations. Responsibilities include site and vendor selection, preparing clinical trial budgets, and ensuring studies are conducted within clinical trial protocols. These roles also involve monitoring progress and following up with team members and line managers when issues develop. Additionally, they implement and prepare the clinical development strategy as outlined by the clinical teams and may develop trial recruitment strategies. Impact and Contribution Roles within Clinical Project Management job family at the M23 level significantly impact the success of clinical trials by ensuring that all aspects of the study are conducted efficiently and effectively. By gathering input from cross-functional teams and creating detailed plans, these roles help ensure that deliverables are produced on schedule, contributing to the overall success of the clinical trials. Their oversight of operational aspects of clinical trials ensures consistency and adherence to SOP, GCP, and country regulations, which is crucial for the integrity and reliability of the study results. Additionally, their involvement in site and vendor selection, budget preparation, and monitoring progress helps maintain the smooth operation of clinical trials, ultimately contributing to the advancement of clinical research and development. Core Focus • Planning, directing, creating, and communicating clinical study timelines • Overseeing operational aspects of clinical trials • Ensuring consistency across clinical studies • Adhering to SOP, GCP, and country regulations • Selecting sites and vendors • Preparing clinical trial budgets • Monitoring progress and following up with team members and line managers • Implementing and preparing the clinical development strategy • Developing trial recruitment strategies