Staff Laboratory Automation Engineer
San Diego Stealth Startup
We are seeking an experienced Staff Laboratory Automation Engineer to own the design, scripting, deployment, and ongoing support of Hamilton VENUS liquid-handling automation across core laboratory workflows.
This is a hands‑on, platform‑expert role supporting an accelerated laboratory launch. The successful candidate will bring production‑grade Hamilton VENUS expertise from day one and serve as a senior technical authority for laboratory automation.
Responsibilities:
- Design, script, test, optimize, and deploy Hamilton VENUS methods supporting library preparation, extraction, and sample‑processing workflows.
- Configure deck layouts, labware definitions, liquid classes, pipetting parameters, tip strategies, and exception/error‑handling logic.
- Translate molecular biology protocols into reliable, reproducible, and scalable automated workflows.
- Build and maintain standardized deck configurations, reusable method components, labware libraries, and liquid‑class standards.
- Integrate Hamilton platforms with peripheral instrumentation, including thermal cyclers, plate sealers/peelers, barcode readers, robotic arms, and other laboratory devices.
- Serve as the senior escalation point for method failures, instrument faults, and liquid‑handling performance issues; perform root‑cause analysis and implement corrective solutions.
- Partner with R&D, Lab Operations, and Quality on IQ/OQ/PQ, method validation, change control, and production releases.
- Maintain method documentation, version histories, validation records, and technical specifications.
- Partner with LIMS and Software Engineering to ensure sample manifests, run logs, plate maps, and sample‑level data integrate reliably with laboratory systems.
- Establish automation development, scripting, testing, and documentation standards and review methods prior to production deployment.
- Mentor engineers and laboratory partners on Hamilton VENUS capabilities, troubleshooting, and automation best practices.
- Collaborate cross‑functionally with scientists, engineers, Quality, and Lab Operations to support laboratory readiness, workflow improvements, and future automation initiatives.
- BS with 8+ years, MA with 6+ years or PhD with 3+ year of experience in life sciences, engineering or computer science.
- Deep, production‑grade Hamilton VENUS expertise required from day one, including method scripting, deck design, liquid‑class development, pipetting optimization, and troubleshooting.
- 6+ years of hands‑on experience developing, deploying, and supporting laboratory automation using Hamilton STAR, STARlet, Vantage, or similar platforms.
- Strong understanding of molecular biology and laboratory workflows, including library preparation, extraction, and sample processing.
- Experience integrating liquid handlers with third‑party laboratory instrumentation and peripheral devices.
- Familiarity with validation, documentation, and change‑control requirements within CLIA/CAP, GxP, or similarly regulated environments.
- Strong troubleshooting, root‑cause‑analysis, and independent technical decision‑making capabilities.
- Ability to operate effectively in a fast‑paced environment and independently drive complex automation issues through resolution.
- Experience with additional automation platforms such as Agilent Bravo or Tecan Fluent.
- Programming or scripting experience with Python, C#, Java, or similar languages.
- Experience integrating laboratory automation with LIMS/LIS and laboratory informatics systems.
- Experience supporting complex, high‑throughput laboratory automation environments.
We are an equal opportunity employer. We thrive on diversity and collaboration.
#J-18808-Ljbffr$178k - $190k
...Senior Staff Surface Process Engineer / Surface Chemist Job Type: Full-Time Salary Range: $178,000 - $190,000 Company We are a rapidly... ...Develop and troubleshoot surface processing methods using laboratory equipment, including vapor deposition systems, plasma...SuggestedFull time- ...solutions to complex environmental and engineering challenges. We listen to our clients and... ...We are currently seeking a Staff Geologist, Scientist, or Engineer with... ...with subcontractors, including drillers, laboratories, utility locators, and other field service...SuggestedFor contractorsFor subcontractorWork at officeFlexible hours
$159.43k
...Collect and manage environmental and geotechnical samples for laboratory analysis • Install and maintain groundwater monitoring wells/... ...member of the CDM Smith Inc. and its divisions and subsidiaries staff will not be considered binding terms. All unsolicited resumes sent...SuggestedFor contractorsWork experience placementH1bImmediate startFlexible hours- ...and Enterprise, Song, Supply Chain and Engineering, and Talent, with advanced capabilities... ...at accenture.com.You are:The Robotics Automation Engineer understands the broader Physical... ..., warehousing, logistics, engineering, laboratories or other asset-intensive environments....SuggestedWork experience placementLive inWork at officeLocal area
$35.6 - $54.3 per hour
...Staff UAS Flight Test Operator Shield AI is a venture-backed defense-tech company with the mission of protecting service members... ...features, capabilities, and operational performance in representative laboratory and flight environments. The operator is responsible for the...SuggestedFull timeTemporary workPart timeRemote workWorldwide$90k - $105k
...subsidiary of Alutiiq, LLC has an excellent opportunity for a Robotics Engineer in San Diego, CA. This position will be part of the US Navy... ...and Technology for Obsolescence, Restoration, and Evaluation) Laboratory supporting engineering services for the U.S. Government. This...$135k - $165k
...Aspen Neuroscience is at the forefront of autologous stem-cell therapies, and we are looking to add a Senior Automation Engineer to our growing team. The Senior Automation Engineer will support the development, improvement, maintenance, and operation of complex custom...Work at officeRelocationWeekend work$47 - $53 per hour
...Automation Equipment Engineer We are seeking a Senior Automation Equipment Engineer to support the development, integration, commissioning, and ongoing improvement of pilot-level semi-automated and fully automated manufacturing equipment. This is a hands-on engineering...Contract workTemporary workMonday to Friday$106.8k - $120.15k
...maintaining, diagnosing, repairing, and upgrading automated control systems and instrumentation,... ...-related documentation. The Automation Engineer III will lead technical assessments and... ...of GMP, aseptic techniques, and laboratory complianceHighly proficient in Microsoft...Full timeWork at officeFlexible hours$110k - $125k
...Automation EngineerWARNING about fake job posting scams. There has been a recent wave of... ...This dynamic role is a part of a team of engineers and scientists developing a novel... ...programsWorking ConditionsGeneral Office, Laboratory, and Cleanroom environmentsExpected travel...Work at officeLocal areaFlexible hours$100k - $110k
...GovCIO is currently hiring for an Automation Engineer tosupport data analysis, process automation, data configuration, workflow configuration, and reporting activities at Department of Homeland Security (DHS) Immigration and Customs Enforcement (ICE). This role will work...For contractorsCurrently hiringWork at officeFlexible hours$110k - $140k
...range $110,000.00/yr - $140,000.00/yr *THIS IS NOT A SOFTWARE ENGINEERING ROLE* Job Responsibilities : Partner with stakeholders,... ...teams Understand & optimize MolBio processes – Design & enhance automation solutions Collect & analyze data from automation platforms to...Full time- ...Build the Next Generation of CNC Automation at 5th Axis At 5th Axis , we’re global leaders in precision machining, automated production... .... We’re looking for a Senior Automation & Controls Engineer who can turn challenging machining applications into safe, reliable...
$142.8k - $196.35k
...Controls Department is responsible for the development and engineering of the metrology, automation and control loops for the EUV light source system. The... ...inventions and products. Plans and executes laboratory research pertaining to algorithm design and validation...Immediate startRemote workFlexible hoursShift work2 days per week$61.9k - $141k
...Network Automation EngineerWe are seeking an experienced automation engineer for the management of system infrastructure and applications. As an automation engineer at Booz Allen, you can use your technical skills to affect mission-forward change.You'll work with a cross...Full timeContract workPart timeLocal areaRemote work- ...Automation /Controls Engineer, San Diego, CAVerus is looking for a self-motivated, organized, and results-driven Controls Engineer to join our collaborative team. Someone who is passionate about solving complex problems alongside our clients.Our clients are important to...Work at officeFlexible hours
- ...documentation, runbooks, and handoff materials Provide engineering support for the first 1-2 deployments , then transition to... ...layered PLC/controls architectures ~ Background in industrial automation (material handling, conveyance, sortation, manufacturing)...Remote work
$61.9k - $141k
...Job Number: R0252127 Network Automation Engineer The Opportunity: We are seeking an experienced automation engineer for the management of system infrastructure and applications. As an automation engineer at Booz Allen, you can use your technical skills to affect...Full timeContract workPart timeLocal areaRemote work$90k - $130k
...Title: Thermal Test Python Automation Engineer Location: San Diego CA (Day 1 onsite/5 days in office) Duration: Fulltime Salary Range: $90000-$130000 a year Job Description:- 3 years of experience in QA and test automation with a strong foundation in...Full timeWork at office- Job Title: Nuclear Engineer (Naval Reactors Engineer) Category / Component: Officer • Active... ...and associated Department of Energy laboratories and shipyards. Key Responsibilities Provide... ...career as part of a lean headquarters staff; work primarily in an analytical and oversight...Contract workApprenticeshipWork at office
- ...Qualifications: ~ Bachelor's degree in Mechanical or Electrical Engineering or equivalent experience. ~3-5 years of technical sales... ...related sector (Hydraulics, Pneumatics, Bearings, Robotics, Automation) ~ Proven ability in managing sales territories and achieving...Work from home
$50 per hour
...to $50 USD/hr. Weekly payments. Trusted by 10,000+ software engineers worldwide MIN EXP REQUIRED 2+ years PAY RATE Up to... ...Qualifications ~2+ years of experience in backend engineering, AI automation, or complex systems integration. ~ Proven ability to build...Weekly payExtra incomeContract workFreelanceInternshipRemote workWorldwide$100k - $199k
...healthcare customers to deliver our broad portfolio of analytical solutions, and OneSource services.Job TitleSenior/Manager, Automation Engineering (cGMP) - Project FarmaLocation(s)Boulder, CO, Boulder, CO, Cambridge, MA, Columbus, OH, Concord, NC, Customer Site - AL,...Full timeWork visa$35 - $41 per hour
.../5:00 p.m. Position Overview Join the Equipment Engineering team to support a laboratory equipment project, including instrument onboarding, maintenance... ...chemicals. Requirements Proficiency in automation maintenance, upkeep, repairs, calibration requirements...Contract work- ...report onsite to our San Diego, CA. location. Remote or hybrid is not available. Axos Bank is seeking a Head of AI and Automation Engineering – Commercial & Securities group. This exciting, new role exists to make Operational Transformation's mission real: using AI...Full timeRemote work
$97k - $116k
...team. POSITION TITL E : Building Automation Specialist POSITION SUMMARY: The... ...monitoring systems that serve laboratory, vivarium, and general campus HVAC and mechanical... ...for coordination with other facilities staff. Ability to lift and carry heavy objects...For contractorsFlexible hours$150k - $170k
...our San Diego, CA. location. Remote or hybrid is not available. Axos Bank is seeking a First Vice President of Platform & Automation Engineering. This exciting, new role exists to make Operational Transformation's mission real: using AI and automation to drive operational...Full timeWork at officeLocal areaRemote work- ...Building Automation Specialist (Distech/Niagara Controls Experience) Job Duties & Responsibilities: Provide Controls database, graphics, programming, etc. for sequences as provided by the Design Specialist, project specifications, or other applicable sources....For contractors
- ...Overview Joby Aviation is seeking a highly organized and passionate engineer to support our composite materials qualification effort,... ...characterization and coordinate with material & process test laboratory to execute engineering work orders Analyze composite material...
$181.8k - $272.6k
...including modifications, upgrades, and maintenance of the product or product line. Minimum Qualifications: ~ Bachelor's degree in Engineering, Information Systems, Computer Science, or related technical field. ~5+ years of Product Management or related work experience....Temporary workWork experience placementImmediate startWork from home
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Staff Laboratory Automation Engineer. Be the first to apply!
- senior staff systems engineer San Diego, CA
- assistant mechanical engineer San Diego, CA
- assistant engineer San Diego, CA
- project engineer assistant project manager San Diego, CA
- engineering aide San Diego, CA
- staff engineer San Diego, CA
- software engineer staff San Diego, CA
- senior staff engineer San Diego, CA
- technology administrator San Diego, CA
- autonomous systems engineer San Diego, CA





