Lead Mechanical Engineer
CRG - Triad
Mechanical / HVAC Lead Engineer
LJC is seeking a Mechanical / HVAC Lead Engineer to provide technical leadership in the planning, design, and delivery of building mechanical systems for life sciences manufacturing facilities, including pharmaceutical and biotechnology production environments. This role focuses on air-side systems and building-side mechanical utilities that support manufacturing operations, cleanrooms, and controlled environments, with laboratory and office spaces comprising a smaller portion of overall project scope.
The Mechanical / HVAC Lead Engineer plays a key role in early project definition, system strategy development, and multidisciplinary coordination within a design-build delivery model. This position is suited for a licensed mechanical engineer experienced in manufacturing-focused life sciences facilities and complex, regulated environments.
The Specifics of the Role
- Lead the design of building mechanical systems for life sciences manufacturing projects, including HVAC and building-side wet utilities, from early planning through construction support.
- Develop air-side system strategies that support manufacturing cleanrooms and controlled environments, including pressure relationships, air change rates, filtration, redundancy, and system resiliency.
- Plan and coordinate building-side wet utilities such as plant steam, heating hot water, chilled water, condenser water, domestic water, and sanitary and industrial waste systems.
- Collaborate with architects, engineers, and construction teams to integrate mechanical systems with manufacturing layouts, equipment rooms, and support spaces.
- Support front-end project efforts by contributing to proposals, system narratives, conceptual layouts, and client presentations.
- Lead technical discussions with clients related to system performance, operational reliability, energy use, maintainability, and lifecycle considerations.
- Coordinate with construction teams to support design-build delivery, constructability reviews, and phased execution strategies.
- Develop and/or review calculations, drawings, and specifications to ensure quality, consistency, and alignment with project and regulatory requirements.
- Ensure compliance with applicable codes, standards, and guidelines, including ASHRAE, NFPA, GMP/GxP, and local regulations.
- Participate in multidisciplinary coordination reviews to ensure mechanical systems are fully integrated with architectural and other engineering systems.
- Mentor and support the development of junior mechanical engineers and designers.
- Contribute to the development of LJC's mechanical design standards, tools, and best practices for life sciences manufacturing facilities.
Requirements
- Bachelor's degree in Mechanical Engineering or a related field.
- Professional Engineer (PE) licensure required.
- 10–20+ years of experience designing building mechanical systems for life sciences manufacturing, pharmaceutical, biotechnology, or other regulated production facilities.
- Demonstrated experience leading HVAC and building-side mechanical utility design on manufacturing-focused projects.
- Strong understanding of air-side systems and building-side wet utilities supporting manufacturing cleanrooms and controlled environments.
- Experience coordinating mechanical systems with manufacturing layouts, electrical systems, and building infrastructure.
- Working knowledge of applicable codes and standards, including ASHRAE, NFPA, GMP/GxP, and relevant local regulations.
- Experience working in a design-build or fast-track project delivery environment preferred.
- Strong communication skills, with the ability to lead technical discussions, client meetings, and pursuit presentations.
- Familiarity with Revit and BIM-based coordination workflows.
- Ability to collaborate effectively across multidisciplinary teams and manage multiple priorities.
Some Things You Should Know
- Our clients and projects are nationwide
- No other builder can offer the collaborative design-build approach that Clayco does.
- We work on creative, complex, award-winning, high-profile jobs.
- The pace is fast!
Why Clayco and LJC?
- 2025 Best Places to Work – St. Louis Business Journal, Los Angeles Business Journal, and Phoenix Business Journal.
- 2025 ENR Top 400 – Top Data Center Contractor (Top 3).
- 2025 ENR Top 100 Design-Build Firms – Design-Build Contractor (Top 5).
- 2025 ENR Top 100 Green Contractors – Green Contractor (Top 3).
Benefits
- Discretionary Annual Bonus: Subject to company and individual performance.
- Comprehensive Benefits Package Including: Medical, dental and vision plans, 401k, generous PTO and paid company holidays, employee assistance program, flexible spending accounts, life insurance, disability coverage, learning & development programs and more!
Compensation
- The salary range for this position considers a wide range of factors in making compensation decisions including but not limited to: Education, qualifications, skills, training, experience, certifications, internal equity, and location. Compensation decisions are dependent on the facts and circumstances of each case.
$135k - $210k
...Description Burns & McDonnell has an exciting opportunity for a Lead Mechanical Engineer to join the Power global practice. This position is responsible for the design and evaluation of mechanical systems associated with coal and natural gas fired generation facilities...SuggestedFull timeWork experience placementLocal area- Gilder Search Group is looking for a Senior Mechanical Engineer to lead the mechanical design of mission-critical facilities. This role involves ensuring successful delivery of engineering solutions for projects such as data centers and advanced manufacturing plants. With...Suggested
- Bowman is looking for an Engineer V specializing in Mechanical for the Oil & Gas sector in Houston, TX. The role involves leading the mechanical engineering team, overseeing the design and integration of systems, and ensuring compliance with engineering standards. The...Suggested
- CRB is seeking a Mechanical Engineer III in St. Louis, Missouri. In this role, you will design HVAC and mechanical systems for various projects while mentoring junior team members. You will lead project scope and collaborate with multidisciplinary teams to deliver high-...Suggested
- An established industry player is looking for a skilled Mechanical Engineer to join their dynamic team. This role focuses on HVAC and plumbing system design, as well as conducting facilities condition assessments for government and military buildings. The ideal candidate...Suggested
- A leading design and engineering firm in St. Louis seeks a Mechanical / HVAC Lead Engineer to oversee the planning and design of mechanical systems in life sciences facilities. This role requires strong experience in HVAC and building utilities, and the ability to lead...
- A leading engineering firm in St. Louis seeks a Lead Mechanical Engineer to oversee mechanical design projects, including HVAC systems, plumbing, and fire protection. You will collaborate with multidisciplinary teams to deliver innovative and high-quality engineering solutions...
$135k - $210k
A leading engineering firm is seeking a Lead Mechanical Engineer to manage the design and evaluation of mechanical systems for coal and natural gas generation facilities in St. Louis. Responsibilities include front-end planning, overseeing compliance, and leading mechanical...- Massman Construction Co. is seeking a Mid-Career Engineer in St. Louis, MO, responsible for overseeing on-site project administration and engineering for complex water infrastructure projects. The ideal candidate has at least 5 years of experience and a Bachelor's degree...Contract work
- Colliers International is seeking a Lead Building Engineer in St. Louis, Missouri. In this role, you will oversee maintenance systems, respond to client requests, conduct inspections, and maintain relationships with property managers. The ideal candidate will have at least...Work at office
- ...contributions truly matter. Be part of something bigger—build your future with us! Under the general direction of the VP of Engineering, the Mechanical Engineer for Manufacturing is a hands-on position that is responsible for implementing, modifying and maintaining...Work at office
- ...turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across... ...construction. The Role We Want You For The Entry-Level Mechanical Engineer will support the mechanical design of mission-critical...For contractorsCasual workInternshipFlexible hours
- ...turnkey real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across... ...design, and construction. The Role We Want You For The Mechanical Engineer will support the design of mechanical systems for mission...For contractorsCasual workLocal areaFlexible hours
$85k - $115k
...Job Description Job Description Position: Mechanical Engineer III Location: Seattle, WA / Newport, KY / Orlando, FL / Belleville, IL / St. Louis, MO / Milwaukee, WI / Bentonville, AR Years of Experience: 5+ Years About RTM: RTM Engineering Consultants...Flexible hours- ...Description Job Description Job Description: Intermediate Mechanical Engineer You will be responsible for the development of engineering... ...and review equipment specifications and documentation. Lead and supervise efforts associated with mechanical equipment layouts...Visa sponsorshipRelocation package
- ...Job Description Company Description CRB is a leading provider of sustainable engineering, architecture, construction and consulting solutions... ...creativity and execution. Job Description As a Mechanical Engineer III, you’ll play a key role in designing mechanical...For contractors
- ...individual will provide project management and mechanical (HVAC) design services on a variety of... ...degree in Architectural or Mechanical Engineering, Professional Registration, and at... ...environment. ~401(k) with industry-leading match and generous profit sharing. ~...Casual workFlexible hours
- ...Job Description Job Description Description: McClure Engineering is currently seeking a Mechanical Engineer to work alongside other talented engineers dedicated to engineering excellence on a wide range of projects involving complex buildings, data centers and campus...Temporary workSummer workCasual workInternshipLocal areaRemote workFlexible hours1 day per week
- ...Description Job Description Description: · Perform necessary engineering functions required for the project to include field... ...designers, drafters, and engineers. · Collaborate with the mechanical Drafter/Designer on the production of construction documents...Temporary workSummer workCasual workLocal areaRemote workFlexible hours1 day per week
- ...real estate development, master planning, architecture, engineering, and construction firm that safely delivers clients across... ...construction. The Role We Want You For The Senior Mechanical Engineer will lead the mechanical design of projects, provide technical expertise...For contractorsCasual workLocal areaFlexible hours
- ...through construction, coordination with the client, utilizing and coordinating internal resources Qualifications: ~ BS in Mechanical Engineering ~2-5 years minimum experience in a related field ~ PE or EIT required ~ LEED Accreditation a plus ~ Proficient with...
- ...Job Description Job Description We are seeking a Mechanical Design Engineer. This role is ideal for someone who thrives in a hands-on environment and is experienced with 3D modeling and design for manufacturing. You’ll be involved in projects from concept through...Temporary workFor contractors
$80k - $120k
...Job Description Job Description Mechanical Engineer / Project Manager St. Louis, MO Direct Hire/ Permanent Placement $80k-$120k, Hybrid, Full Benefits, Bonuses, 401k match EPC STAFF works with Architectural, Engineering, and Construction Firms and MEP...Permanent employment- ...Job Description Job Description POSITION TITLE: ENGINEER I REPORTS TO: ENGINEERING MANAGER Position Summary: Perform... ...troubleshooting and development and honing applications Mechanical Emphasis Position As directed, design small mechanical...Work at office
- ...across 30 companies work together to deliver exceptional HVAC, mechanical, plumbing, refrigeration, and electrical solutions nationwide.... .... We only accept direct applications. Mechanical Design Engineer – HVAC & Plumbing Systems About NDBS National Design Build...Full timeLocal areaRemote work
$105k - $145k
...Process Mechanical Lead Engineer At Jacobs, we're challenging today to reinvent tomorrow by solving the world's most critical problems for thriving cities, resilient environments, mission-critical outcomes, operational advancement, scientific discovery and cutting-...Full timeWork at officeRemote workWorldwide- ...seeking an experienced Structural Analysis Engineer to support our customer, Boeing Defense... ...’s Degree in Aerospace Engineering, Mechanical Engineering, or related engineering discipline... ...finite element modeling. Experience leading technical teams or mentoring junior...
- ...Description Position Summary Commitment to leading a mission critical environment that... ...the installation and maintenance of mechanical systems at Data Centers and operations... ...cooling systems. Acts as an Engineering resource for the complete H5 portfolio...Work at officeImmediate start
- ...JOB SUMMARY The Mechanical Engineer I is responsible for the design, development, documentation, test, and evaluation activities for components, sub-assemblies, and finished goods products that meet the cost, performance and timeliness requirements defined within...Work at office
- ...Mechanical Engineer Job Description Job Information Job Title Mechanical Engineer Reports To... ...About Murphy Company Since 1907, Murphy Company has been a leading mechanical contractor in the St. Louis and Denver markets that...For contractorsWork at officeFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Lead Mechanical Engineer. Be the first to apply!
- lead engineer Saint Louis, MO
- lead operating engineer Saint Louis, MO
- mechanical engineer hvac Saint Louis, MO
- mechanical design Saint Louis, MO
- mechanical commissioning Saint Louis, MO
- entry level mechanical design Saint Louis, MO
- mechanical foreman Saint Louis, MO
- mechanical inspector Saint Louis, MO
- mechanical installation Saint Louis, MO
- lead support engineer


