Director, IT Operations

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor-all in service of patients. The Opportunity: The Director of IT Operations will lead enterprise IT operations, service delivery, and operational strategy as Revolution Medicines scales globally and prepares for commercialization. This leader will oversee enterprise platforms, infrastructure, and IT service management while driving operational excellence through automation, AI-enhanced operations, standardized processes, and resilient enterprise services. IT Operations & Service Delivery Lead global IT operations, including service desk, endpoint engineering and infrastructure, and enterprise application support. Deliver reliable, scalable IT services aligned with company growth and international expansion initiatives. Lead and mature IT service management practices, including ITSM and ITAM capabilities within ServiceNow. Drive continuous improvement in employee experience through modern service delivery, self-service, automation, and AI-assisted support. AI, Automation & Intelligent Operations Define and execute a strategy for AI-enhanced IT Operations (AIOps) to improve service reliability, operational efficiency, and user experience. Identify and implement GenAI and LLM-based solutions to enhance: Service desk automation and virtual agent capabilities. Incident triage and root cause analysis. Knowledge management and documentation generation. End-user self-service and operational workflows. Partner with Security, Legal, and Data teams to establish governance, compliance, and safe usage frameworks for AI technologies. Drive adoption of AI-assisted workflows across IT operations to reduce manual effort and improve scalability. Evaluate and integrate AI capabilities within enterprise SaaS platforms and operational workflows. Establish meaningful and measurable operational outcomes and ROI metrics for automation and AI initiatives. Platform Infrastructure Ownership Oversee cloud-first infrastructure, endpoint management, enterprise collaboration platforms, and storage environments across Microsoft and AWS ecosystems. Identity Operations Ensure secure identity lifecycle management aligned with Entra ID and automated provisioning strategies. Partner with Security to enforce Zero Trust architecture leveraging Zscaler and modern network controls. Assure and drive compliance with regulatory requirements (SOX, GxP). Asset, Vendor & Financial Management Develop and manage the annual IT Operations budget to ensure alignment with enterprise and IT strategic objectives. Own software and hardware asset management, licensing, and vendor relationships, with a focus on cost optimization and governance. Improve visibility into SaaS utilization, forecasting, lifecycle management, and operational spend. Ensure technology investments-including AI platforms-align with business value and ROI. Team Leadership & Development Build and lead a high-performing global IT operations team through mentorship, clear accountability, talent development, and a culture of continuous improvement. Develop team capabilities in automation and modern IT operational practices. Business Partnership & Strategy Partner with business stakeholders, Security, HR, Engineering, and regional IT leadership to deliver integrated technology solutions aligned to corporate growth, digital transformation, and operational scalability. Required Skills, Experience and Education: 15+ years of progressive IT experience, including 5+ years in IT Operations, Infrastructure, or Service Delivery leadership roles within a medium-to-large enterprise environment. Proven experience leading and scaling IT operations in a fast-growing, global organization. Strong experience managing SaaS-first and cloud-centric environments, including Microsoft 365, Entra ID / Azure AD, ServiceNow, Intune, JAMF, Azure, and AWS platforms. Experience with identity and access management, endpoint management, ITSM/ITAM, automation, and enterprise operational governance. Experience implem #J-18808-Ljbffr revolutionmedicines