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Senior Scientist I/II, Analytical Chemistry- Predictive Stability, Mass Spectrometry

BioSpace

Job Description AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie’s pharmaceutical products. The Senior Scientist II will conceive, implement, and execute novel scientific research and development, generating new proposals and leading efforts in the Predictive Stability and Structure Elucidation team. Responsibilities Apply analytical separation and detection modes for complex impurity profiling of pharmaceutical products to better understand emerging cGMP manufacturing processes. Lead the predictive stability aspects of a project while working with other functional areas to advance projects through the development pipeline. Utilize a range of analytical techniques to conduct research and development studies related to small‑molecule drug products, active pharmaceutical ingredients, intermediates, starting materials, impurities, and impurity profiling. Support new product development with advanced methods development and validations, technical transfer packages, and generation of technical data in support of regulatory requirements. Operate autonomously and productively in laboratory research or method development, requiring only minimal direction or interaction with supervisors. Formulate conclusions and design follow‑on experiments based on multidisciplinary data. Initiate new areas of investigation that are scientifically meaningful and can be incorporated directly into a research or development program. Process, interpret, and visualize data to facilitate project‑team decisions. Communicate and collaborate with cross‑functional groups and departments. Demonstrate scientific initiative and creativity in research or development activities and maintain a high level of productivity in the lab. Develop, test procedures, and implement analytical control strategies to advance drug discovery candidates. Continuously raise the bar and seek improvement beyond the status quo. Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, and GxP compliance where applicable. Qualifications Bachelor’s, Master’s, or Ph.D. in Analytical Chemistry with a minimum of 12 (BS), 10 (MS), or 4 (Ph.D.) years of related industry experience. Practical understanding of organic chemistry reactions related to potential degradation mechanisms of small molecules and peptides. Experience with structure elucidation for small molecules, particularly by high‑resolution mass spectrometry (Orbitrap, QTOF, etc.). Experience developing LC‑MS methods for trace quantitation is a plus. Some experience using computational tools to model chemical processes or reactions. Strong technical background in analytical chemistry and excellent analytical problem‑solving skills. Hands‑on experience with HPLC analysis and method development; expertise in spectroscopic techniques. Self‑motivated, detail‑oriented, and able to work in a fast‑paced team environment. Experience with computerized data handling systems. High‑quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers. Practical knowledge of organic structure, functional groups, chemistry, and modern spectroscopic techniques applied to small‑molecule analysis. Builds strong relationships with peers and partners across the organization. Learns quickly and can change course promptly when needed. Creates an open learning environment, welcoming suggestions and experimentation for improvement. Embraces ideas of others, nurtures innovation, and manages innovation toward reality. Compensation and Benefits The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting, based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits, including paid time off (vacation, holidays, sick) and medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short‑term incentive programs. Note: No amount of pay is considered wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. Equal Opportunity Employer AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer / Veterans / Disabled. US & Puerto Rico only – to learn more, visit US & Puerto Rico applicants seeking a reasonable accommodation: #J-18808-Ljbffr BioSpace

Vacancy posted 2 days ago
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