Program Manager, Center Operations

Program ManagerThe Yale Center for Systems and Engineering Immunology (CSEI) seeks a Program Manager to lead the operational and programmatic infrastructure of a rapidly growing research center, and to serve as the principal operational partner to the Center Director.This is a broad, high-autonomy role for an experienced research operations professional. You will own CSEI's programmatic calendar — its seminar series, conferences, workshops, and trainee programs — and manage the Center's external communications, membership, and institutional relationships. In parallel, you will manage the Director's institutional commitments, engagement portfolio, and travel program, exercising independent judgment daily on competing priorities across a research enterprise spanning multiple funded programs and collaborators on multiple continents.Principal responsibilities include:Own the design and execution of CSEI's programs, including the Center seminar series, scientific workshops, and Center-led conferences.Lead the annual speaker nomination process: solicit and curate nominations from CSEI faculty and trainees, and work with Center leadership to finalize the slate. Manage speaker invitations, visit programs, and hospitality end to end.Develop and steward trainee-led programming, including the trainee speaker invitation program and the Center journal club, partnering with postdoctoral and graduate trainees to build durable, self-sustaining community programs.Direct logistics and delivery for Center conferences and multi-day scientific meetings, including venue, budget, registration, materials, and speaker coordination.Supervise student workers, temporary staff, and vendors engaged in support of Center programming.Exercises independent judgment to resolve project commitment conflicts, sequence competing demands, and protect capacity for research leadership and strategic work.Conduct a daily coherence review across all projects, identifying and resolving conflicts.Negotiate and coordinate meeting agendas and commitments with senior collaborators, sponsors, and institutional leaders across US, European, Asian, and Australian time zones.Manage correspondence on behalf of the Director, exercising discretion and independent judgment in triage, prioritization, and drafting of responses to sponsors, collaborators, and institutional offices.Manage the Center's regulatory compliance calendar, including IRB protocol renewals, amendments, and coverage across funded programs; alert program leadership well in advance of deadlines.Coordinate administrative deliverables across multi-institutional consortia, serving as the operational point of contact for partner institutions in the US, UK, Belgium, Hong Kong, Nicaragua, and Bangladesh.Own CSEI's external communications strategy and execution, including the Center's professional social media presence, and grow the Center's visibility within the scientific community.Represent CSEI administratively with Yale University and School of Medicine offices, and coordinate the Center's participation in institutional initiatives and cross-program partnerships.Administer the Center's programmatic budget, including seminar series, conferences, and events; track expenditures, reconcile accounts, and report on financial position to the Director.Manage vendor relationships and procurement for Center programming in accordance with University policy.Hold accountability for the integrity and continuity of the Center's human subjects research protocol portfolio, spanning multiple funded programs and international cohort studies.Direct the preparation and submission of new protocols, amendments, and continuing reviews, working with investigators to translate scientific plans into regulatory submissions and resolving reviewer questions on the Center's behalf.Establish the Center's standards and procedures for protocol maintenance, documentation, and audit readiness, and hold the Center accountable to them.Decide and negotiate the Center's approach to single IRB and reliance arrangements for multi-site studies, coordinating with partner institutions.Monitor the regulatory obligations attached to each award and determine how they are met across the portfolio, escalating to the Director only where scientific or institutional judgment is required.Required skills and abilities include:Bachelor's degree and a minimum of five years of progressively responsible experience in research program management, clinical research operations, or academic administration; or an equivalent combination of education and experience.Demonstrated ownership of complex, concurrent projects with independent responsibility for timelines, deliverables, and stakeholder coordination in a research or academic setting. Experience managing high-volume, multi-source commitment portfolios for senior leadership, with proven capacity to exercise independent judgment on prioritization under shifting conditions.Experience coordinating across institutional boundaries, including with regulatory, compliance, or sponsor organizations. Budget tracking and financial reporting experience.Excellent written communication, with the ability to draft correspondence, reports, and public-facing materials representing an institution. Demonstrated discretion and sound judgment handling confidential information.Preferred skills and abilities include:Advanced degree in public health, policy, life sciences, health administration, or a related field.Experience in an academic medical center, research institute, or university research setting.Working knowledge of IRB processes, human subjects research regulation, or research compliance frameworks.Experience coordinating across international time zones and with global research partners. Familiarity with Yale, NIH, or comparable institutional financial, travel, and procurement systems.Genuine interest in biomedical science, global health, or research policy. This Center's work is mission-driven, and candidates energized by that mission will find the role most rewarding.