Upstream Process Engineer

This range is provided by Harba Solutions Inc.. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$110,000.00/yr - $146,000.00/yr

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Responsibilities

• Independently design and execute experiments to optimize upstream manufacturing processes for viral vector production.
• Perform statistical analysis of experimental data to identify trends and support process improvements.
• Develop and apply empirical or theoretical models to predict process performance and enhance process understanding.
• Evaluate, test, and implement innovative upstream technologies.
• Collaborate cross-functionally with downstream process development, analytical development, and research teams to ensure high product quality and seamless process integration.
• Provide technical support for the successful transfer of processes to contract manufacturing organizations.
• Conduct routine cell culture operations, including bioreactor setup, probe calibration, maintenance, and cell culture passaging.
• Manage experimental data, maintain accurate records using electronic notebooks, and generate comprehensive reports.
• Perform sample analysis using various laboratory analytical tools.
• Contribute to a collaborative team environment by sharing knowledge and supporting team goals.

Qualifications

• PhD in Science, Engineering, or a related field with 2-5 years of experience; or MS with 5-8 years of experience.
• Experienced with mammalian cell culture, bioreactors, AAV production, and upstream process development.
• Knowledge of empirical or theoretical modeling, including machine learning or statistical methods.
• Strong analytical and problem-solving skills.
• Effective communication, organizational, and collaboration abilities.
• Flexibility to work occasional weekends (for active cell culture).
• Familiarity with transient transfections, AAV, automation, and technology transfer is preferred.

The Company

Unlock the opportunity to revolutionize viral vector production in a cutting-edge upstream process development role. Collaborate with a dynamic team to optimize manufacturing processes, integrate innovative technologies, and drive impactful projects. With your expertise in cell culture, bioreactors, and process modeling, you’ll play a key role in advancing groundbreaking therapies. Take the next step in your career and make a lasting impact in a rapidly growing field!

Seniority level

Mid-Senior level

Employment type

Full-time

Job function

Science, Research, and Engineering

Industries

Biotechnology Research, Pharmaceutical Manufacturing, and Manufacturing