Senior Scientist, Immuno-Oncology

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

This Senior Scientist role is in the research and development division. The ideal candidate is a highly energetic and motivated scientist with experience in discovery and development of protein therapeutics. The position requires a strong background in human immunology, and tumor biology, as well as hands-on experience with major biotechnology platforms for biologics drug development Incucyte, Emulate, MSD, FACS, etc.  Candidates with a passion for agentic AI-based system development are highly encouraged to apply.  

This role is full-time onsite at our Redmond, WA location and we will be moving to our new building in Bothell, WA fall 2026.

Responsibilities

• Establish and apply in vitro, and in situ models to identify and characterize novel antibody therapeutics 

• Evaluate novel pathways and mechanisms for immunological therapeutic intervention and formulate strategies for bispecific and therapeutic combination approaches 

• Work as part of highly collaborative interdisciplinary team 

• Prepare written reports to specification and oral presentations on research projects 

• Prepare documents for submission to domestic and international regulatory agencies 

• Lead immuno-oncology discovery/preclinical projects 

• Other duties as assigned 

Qualifications

• PhD in immunology, cancer biology or related field with 2 - 5+ years of relevant academic and/or pharmaceutical or biotech experience 

• Background in human immune cell biology, or immune cell receptor signaling research 

• Expertise in discovery and development of protein therapeutics and mammalian cell culture 

• Research experience in developing bispecific antibodies is preferred 

• Excellent time management and organizational skills 

• Excellent written, oral, and interpersonal communication skills 

• Possess the right attitude (agile, curious, positive, open-minded, “can-do” mindset), and have the ability and strong desire to “make things happen” 

Work Environment 

• Bench top work in a BSL-2 laboratory environment, including potential exposure to biohazards 

• Adherence to Health and Safety standards when working with temperature-controlled systems, including liquid and vapor phase liquid nitrogen  

Physical Demands 

• Occasional lifting to 30 pounds 

• Requires repetitive multi-channel pipetting, single channel pipetting, and computer data entry 

• Fine motor movements in fingers/hands to operate computers and other office and lab equipment, repetitive motion with lab equipment 

• Stooping, bending, crouching, reaching, or climbing ladders 

Position Type/Expected Hours of Work 

• May need to work outside of standard working hours at times 

• This role is currently working onsite and is expected to work onsite for working hours, with flexibility to work start time. The work location for this role is in Redmond, WA

Travel  

• Attendance and participation in national and international conferences encouraged 

Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
 
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
 
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
 
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.