Technical Lead Architect, Global Patient Safety

Job ID: R-108899Company: LillyLocation: Indianapolis, Indiana, United States of AmericaJob Type: Full TimeCategory: Information TechnologyPosted Date: 2026-08-21At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. The Technical Lead Architect is a senior technology leader, responsible for technical architecture, design, development and integration of a broad range of advanced technology solutions for the Patient Safety organization. This role acts as the primary technical authority across Safety systems and their integrations with adjacent platforms (e.g., Quality, Regulatory, Clinical, and Data platforms), ensuring solutions are scalable, compliant, and aligned with business and regulatory requirements. Partnering tightly with Software Product Engineering, Cyber Security, and Infrastructure & Digital Core, the lead architect drives shared strategies and architectures, while researching and applying emerging technology—including AI and agentic engineering—to advance capability and drive adoption.Key ResponsibilitiesOwn the technical direction of complex initiatives across Global Patient Safety, shaping modern, resilient, secure solutions. Lead data and solution integration across the ecosystem, ensuring reliable, performant connectivity between Global Patient Safety systems, data products, and other platforms and systems. Develop and maintain architecture roadmaps, technical standards, and reference architecture for the Patient Safety technology landscape.Research and apply emerging technology—AI/ML, agentic workflows, intelligent automation—driving adoption.Champion modernization and resilience, reducing technical debt and improving fault tolerance, observability, and recoverability. Embed secure and AI-assisted engineering (code generation, automated testing, anomaly detection, threat-aware design) to accelerate delivery and improve operational quality. Serve as a recognized expert, defining integration patterns and engineering standards adopted across Global Patient Safety teams. Elevate technical colleagues by sharing data, integration, and security knowledge to broaden team impact. Assume the role of Technical System Owner for GPS systems, accountable for the technical lifecycle, validated state and compliance.Serve as the technical lead across multiple concurrent projects, providing hands-on guidance to developers, configuration analysts and integration and support teams.Partner with Software Product Engineering, Cyber Security, and Infrastructure & Digital Core to drive aligned strategies, shared standards, and secure-by-design architectures. Basic QualificationsBachelor's degree in Computer Science, Software Engineering, Information Technology, or a related field.8+ years of experience in IT architecture, systems integration, or technical lead roles, of which at least 5+ years of software/systems engineering experience delivering complex, enterprise-scale solutions for Patient Safety Organization, with clear technical ownership. Additional QualificationsStrong communication and cross-functional influencing skills.Experience in Good Pharmacovigilance Practices (GVP), Good Clinical Practice (GCP), or a regulated (GxP) environment within pharmaceutical, biotech, or healthcare. Hands-on experience developing and integrating AI/agentic capabilities into operational systems. Strong understanding of system integration patterns (APIs, middleware, ETL, data mapping) and enterprise architecture principles.Hands-on experience with Safety systems (e.g., Veeva Safety, Oracle Argus).Experience across integrations, APIs, event-driven architecture, and cloud platforms (Azure, AWS, or GCP).Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form () for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (View email address on click.appcast.io), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is$126,000 - $224,400Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.#WeAreLillySkillstechnical architecturesystems integrationpatient safety systemssoftware engineeringenterprise architectureapi integrationmiddlewareetldata mappingcloud platformsazureawsgcpveeva safetyoracle argusgood pharmacovigilance practicesgood clinical practicegxp complianceai/mlagentic workflowsintelligent automationsecure-by-design architecturecode generationautomated testinganomaly detectionthreat-aware designcross-functional leadershipstakeholder managementtechnical standards developmentreference architecture