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Principal Data Scientist - R&D DSDH - Preclinical Sciences & Translational Safety (PSTS)

Scorpion Therapeutics

Principal Data Scientist – R&D DSDH – Preclinical Sciences & Translational Safety (PSTS) Position Summary Use machine learning and data engineering to create AI-ready datasets, build predictive models, and deliver analytics that improve safety evaluations and support translational research within PSTS. Key Responsibilities Develop/deploy ML/AI for safety signal detection, dose selection, PK/PD modeling, toxicology insights, and translational interpretation. Build representation‑learning, predictive, and multivariate models across in vivo, in vitro, exposure‑response, and pathology data. Create scalable pipelines integrating PSTS‑relevant data sources; transform raw outputs into standardized AI‑ready datasets (Python/R/cloud). Partner with toxicology/DMPK/safety SMEs; apply mechanism‑based toxicology and exposure-response concepts; improve cross-study comparability using standardized terminologies, metadata, and quality checks; follow model governance/versioning/validation standards. Qualifications Required MS or PhD in Data Science/Computational Biology/Toxicology/Pharmacology/Biomedical Engineering/Computer Science (or related). 3+ years applying ML/data engineering to scientific/biomedical datasets. Proficiency: Python and/or R, SQL, and modern data engineering (cloud, workflow orchestration, version control). Experience with ML model development/evaluation/deployment; biological/toxicology/PK‑PD/in vivo dataset experience. Preferred Safety sciences; ADME/DMPK; toxicogenomics/biomarker analytics; scientific data formats; ontologies/semantic tech/knowledge graphs. AWS S3/Snowflake/Redshift; SEND/CDISC. Skills (listed) Advanced analytics; data analysis/visualization; data quality & privacy; critical thinking; strategic/technical credibility; workflow/process improvement. Benefits (explicitly listed) Vacation; sick time; holiday pay; work/personal/family time; parental leave; bereavement; caregiver leave; volunteer leave; military spouse time‑off. #J-18808-Ljbffr Scorpion Therapeutics

Vacancy posted 5 days ago
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