Regional Scientific Director, Health Systems & Payer Strategy

Overview

Madrigal is a biopharmaceutical company focused on developing novel therapeutics for metabolic dysfunction‑associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. The company’s medication, Rezdiffra (resmetirom), is a once‑daily, oral, liver‑directed THR‑β agonist approved by the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2‑F3). An ongoing Phase 3 outcomes trial evaluates Rezdiffra for patients with compensated MASH cirrhosis (F4c).

Role Summary

The Health Systems Regional Scientific Director (HSRSD) is a therapeutic and disease expert responsible for building and maintaining professional relationships with healthcare decision makers in defined regional payer organizations (e.g., health plans, PBMs, integrated delivery systems, large GI practices, specialty pharmacy and other key health systems). The HSRSD provides accurate information about Madrigal products, related disease areas, clinical science, and HEOR/real‑world research in a balanced and credible manner consistent with the regulatory environment and Madrigal’s ethical standards. They serve as a resource for the Global Medical Affairs management team on strategic planning, mentor other team members, and collaborate with account executives, key account managers, and other field medical colleagues to address scientific needs in the region.

Locations: Washington, Oregon, Idaho, Wyoming, Utah, Colorado, Kansas, Nebraska, North Dakota, South Dakota.

Primary Activities

• Develop ongoing professional relationships with key decision makers in organized health systems to ensure access to medical and scientific information on Madrigal’s products and related disease areas.
• Partner with Market Access and Key Account Director teams to develop strategic account plans and execute medical activities in alignment with agreed plans.
• Effectively communicate and coordinate with regional MSLs and CPLs regarding medical and scientific support needs in key affiliated regional health systems – IDNs, GI practices, and regional payers.
• Serve as a resource for the Health Systems Executive Director and other members of market access and KAD organizations on relevant strategic planning.
• Provide support for HEOR activities led by HQ HEOR within regional accounts of responsibility.
• Serve as a technical resource on questions raised by market access and KAD team members.
• Attend and support scientific and medical meetings; prepare planned post‑meeting deliverables.

Required Skills and Qualifications

• Clinical or scientific degree required (MD, PharmD, PhD, MS, MPH, etc.).
• 5+ years’ experience in IDN and payer space with the ability to develop peer‑to‑peer relationships with key decision makers; knowledge of payer and IDN organizational practices.
• Thorough knowledge of clinical medicine, the managed market environment, pharmacoeconomics, disease management, real‑world evidence generation, and medical research.
• Business and market knowledge, including quality management, formulary management, and pathway development/management.
• Excellent interpersonal communication skills, strong presentation skills, ability to work with cross‑functional field account teams, strong personal integrity, collaborative mindset, and strong customer focus.
• Comprehensive understanding of FDA, OIG, HIPAA and other ethical guidelines, laws and regulations relevant to the pharmaceutical industry.
• Ability to organize, prioritize, and work effectively in a constantly changing environment; demonstrated project leadership abilities.
• Preferred: Formal training in health economics or outcomes research.

Compensation & Benefits

Base salary range: $240,000 – $265,000 per year. All full‑time employees receive equity as part of our Total Rewards strategy, which also includes base pay, bonus, and equity opportunities. Full‑time employees are eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision, life/disability insurance, 401(k) offerings (traditional, Roth, employer match), additional voluntary benefits, and mental health benefits through an Employee Assistance Program. Benefits are provided in accordance with applicable federal, state, and local laws.

Equal Opportunity & Reasonable Accommodations

Madrigal is an Equal Opportunity Employer. Employment decisions are based on qualifications, merit, and business need, without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, protected veteran, or other characteristic protected by law. The company is committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. For assistance, contact View email address on click.appcast.io .