Clinical Pharmacist II-Investigational Drug Services

Clinical Pharmacist II

About City of Hope Orange County
City of Hope Orange County is transforming cancer treatment by bringing world-class expertise and specialized care closer to home. Supported by a regional network of care, our 11-acre academic cancer campus in Irvine is home to City of Hope Orange County Lennar Foundation Cancer Center, our outpatient cancer center, and Orange County's only cancer specialty hospital, opening in late 2025.


With the opening of the hospital, the full continuum of advanced cancer care-from prevention through survivorship-will be available in Orange County for the first time, eliminating the need to travel for lifesaving treatment. Seamlessly connected to our outpatient cancer center, the new clinical research hospital will feature 73 inpatient beds, advanced surgical suites, groundbreaking clinical trials, and holistic services such as rehabilitative therapy and spiritual care. This isn't standard cancer care. This is lifesaving cancer care. This is Hope.


The Clinical Pharmacist II (CPII) is a licensed professional responsible for reviewing research protocols and extracting key information to provide advanced clinical care. As part of a multidisciplinary healthcare team, the CPII directly supports patients enrolled in City of Hope (COH) clinical trials by managing investigational drug workflows and optimizing medication therapy through Comprehensive Medication Management (CMM).
In this role, the CPII oversees investigational drug processes, supervises technician staff, and collaborates with leadership on operational aspects of the department. The pharmacist ensures compliance with research protocols and investigational drug regulations while actively participating in performance improvement initiatives. Additionally, they contribute to budget planning and financial targets, representing the research pharmacy across multiple disease teams and clinical committees.
This position requires strong collaboration with peers, supervisors, and external stakeholders to foster a team-oriented, problem-solving approach that enhances pharmaceutical care and research integrity.


As a successful candidate, you will:

• Provides comprehensive medication management services, coordinating all clinical pharmacy functions for patients enrolled in clinical trials to help achieve compliant, safe and per-protocol use of investigational drugs
• Completes patient profile reviews and participates in huddles and meetings as an integrated member of the research team.
• Reviews investigational medication regimens for appropriateness, contraindications, and potential interactions.
• Ensures that he or she provides services that are accurate, reliable, courteous, and timely.
• Helps monitor therapeutic plans and medication treatment.
• Orders, reviews, and acts upon appropriate laboratory tests and other diagnostic studies necessary to support a patient's medication therapy regimen.
• Serves as subject matter and clinical expert as related to investigational drug use.
• Collaborates with pharmacy supervisors, leadership, and staff to develop policies, procedures, and processes for more efficient research processing within the pharmacy Enterprise and area of practice.
• Assumes the duties of the Pharmacy Technician/Intern as needed to maintain efficient quality operation and timely service.
• Maintains research logs and records to ensure accuracy and completeness.
• Serves as an authority on drug information; usage, interactions, dosages, and compliance to medical staff, nursing staff, technicians and students.
• Uses appropriate references to research drug information.
• Performs other related duties as assigned or requested.

Your qualifications should include:

• Graduate of ACPE-accredited Pharmacy School or School with ACPE accreditation pending
  PGY1 and PGY2 residencies, or PGY1 plus two years of experience as a clinical pharmacist, or Five years of experience as a clinical pharmacist
• Current CA Pharmacist License, and
• American Heart Association BLS certification
• Preferred Experience: 3 years of experience working in an investigational drug service2 years of experience working in an oncology setting Pharmacy Research

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

To learn more about our Comprehensive Benefits, please CLICK HERE .