Scientist

Job Description

We’re looking for a detail‑oriented Wet Lab Scientist to support a high‑priority binder screening campaign for engineered T‑cell therapies. You’ll operate at the bench, driving the transition from binder discovery to functional validation.

What You’ll Do

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• Engineer primary human T cells using non‑viral delivery (mRNA, transposon DNA; electroporation/nucleofection)
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• Monitor viability, recovery, and receptor expression prior to functional assays
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• Run high‑throughput screening assays for binder affinity and function
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• Maintain/expand primary T cells and Jurkat lines using impeccable aseptic technique
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• Perform multi‑color flow cytometry; analyze data in FlowJo
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• Execute functional assays: cytotoxicity (IncuCyte, LDH), cytokine profiling (ELISA/MSD/Luminex), proliferation (CFSE)
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• Document all work in ELN with precision for data integrity
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What You Bring

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• BS/MS in Immunology, Molecular Biology, Bioengineering, or related field
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• 2+ years hands‑on wet lab experience (industry preferred)
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• Strong aseptic technique; experience isolating primary T cells from PBMCs
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• Expertise in flow cytometry acquisition & analysis (required)
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• Experience with non‑viral transfection methods; comfort with automation/robotics a plus
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• Clear communication and ability to present data in fast‑paced sprint meetings
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