Associate Director, Data Platforms

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. Reporting to Executive Director of Data and Analytics as Associate Director of Data Platforms , you will own the enterprise data platform strategy, architecture, and execution, with a strong focus on Microsoft Fabric. This role is responsible for designing and operating a scalable, secure, and globally available data platform that supports analytical and operational data products. The AD will ensure platform reliability (SLAs), performance, governance, and cost efficiency, while enabling teams to build trusted data pipelines and reusable data products. This role partners closely with Data Engineering, Analytics, AI/ML, Cloud, Security, and Business stakeholders. Key Responsibilities Platform Architecture & Strategy · Own the end-to-end Microsoft Fabric architecture, including Lakehouse, Data Warehouse, OneLake, Data Pipelines, Notebooks, Real-Time Analytics, and Power BI integration. · Define and maintain reference architectures, design standards, and best practices for enterprise data platforms. · Drive global, multi-region scalability, resiliency, and performance of the data platform. · Lead platform modernization, migrations, and roadmap evolution aligned to business needs. Platform Operations & SLAs · Own platform SLAs, SLOs, and operational KPIs (availability, latency, data freshness, cost). · Establish monitoring, alerting, incident management, and on-call processes. · Ensure high availability, disaster recovery, and business continuity for critical data workloads. · Manage platform capacity planning, performance tuning, and cost optimization. Data Pipelines & Engineering Enablement · Provide architectural oversight for batch and streaming data pipelines built on Fabric. · Define patterns for ingestion, transformation, orchestration, and data quality. · Enable CI/CD, automation, and Infrastructure-as-Code for platform components. · Partner with data engineering teams to ensure pipelines are reliable, scalable, and reusable. Governance, Security & Compliance · Define and enforce data governance, security, and access control within Fabric. · Implement metadata management, lineage, auditing, and data classification. · Ensure compliance with regulatory, privacy, and enterprise security requirements. · Partner closely with the Cyber Security and Risk teams to ensure the data platform complies with enterprise security standards, policies, and controls. · Ensure Microsoft Fabric architecture aligns with identity, access management, encryption, network security, and data protection standards. · Support security reviews, threat modeling, audits, and remediation activities for the data platform. Leadership & Collaboration · Act as a technical leader and mentor for platform and data engineering teams. · Partner with Cloud, Security, Enterprise Architecture, and Application teams. · Collaborate closely with Analytics leaders to enable scalable, reliable data pipelines and curated datasets that support enterprise reporting and insights. · Partner with Data Science and Advanced Analytics teams to ensure the platform supports future-ready analytical, AI/ML, and experimentation use cases · Influence stakeholders and leadership through clear communication of platform strategy and trade-offs. · Contribute to vendor engagement and evaluation (Microsoft, tooling ecosystem). Required Qualifications · 10-12+ years of experience in data engineering, data platforms, or cloud architecture. · Strong 2+ hands-on and architectural experience with Microsoft Fabric (or 8+ deep experience in Azure data services with Fabric adoption). · Proven experience designing and operating large-scale, enterprise data platforms. · Experience owning platform SLAs, reliability, and operational excellence. · Strong understanding of data pipelines, Lakehouse architecture, and data warehousing. · Experience with global / multi-region deployments and enterprise security models. · Excellent communication skills with both technical and non-technical stakeholders. Preferred Qualifications · Experience in product-oriented data platforms or data mesh implementations. · Familiarity with DevOps / DataOps, CI/CD, and Infrastructure-as-Code. · Experience supporting AI/ML and advanced analytics workloads. · Prior leadership experience managing senior engineers or platform teams. Competencies · Strategic Thinking: Ability to translate business priorities into an actionable analytics strategy. · Analytical Excellence: Demonstrates strong quantitative skills and ensures rigor, transparency, and clarity in insights. · Influence & Communication: Communicates complex concepts simply, shapes decisions, and engages senior leadership effectively. · Collaboration: Works effectively across functions and builds strong partnerships. · Innovation & Continuous Improvement: Drives modernization, automation, and adoption of new technologies. · Results Orientation: Delivers high-quality work, manages competing priorities, and operates with a bias toward action. Madrigal offers a competitive Total Rewards strategy to attract and retain top talent and is inclusive of base pay, bonus, equity, and a generous benefits package. Full-time employees are eligible for base salary, bonus, equity, and a comprehensive benefits suite. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs, and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $177,000 - $216,000 per year. We comply with all applicable minimum wage laws. All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact View email address on click.appcast.io . Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to View email address on click.appcast.io . #J-18808-Ljbffr