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Senior Manager, PSTS

$137k - $235.75k

Jobleads-US

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function: Project/Program Management Group

Job Sub Function: R&D Project Management

Job Category: Professional

All Job Posting Locations

San Diego, California, United States of America, Spring House, Pennsylvania, United States of America

Job Description

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at

We are searching for the best talent for Senior Manager, PSTS.

The Senior Manager, Strategic & Digital Program Enablement will lead integrated program management and provide programmatic oversight for complex, cross-functional priorities, with an initial focus on the PSTS digital, data science, AI, and technology portfolio. The role will serve as an integrator across the portfolio, helping connect priorities and investments to PSTS business and portfolio priorities and intended scientific, business, operational, portfolio, and enterprise outcomes.

This role will partner across scientific, business, digital, technology, data science, finance, and operational teams to translate strategic priorities into coordinated execution. The Senior Manager will strengthen integrated portfolio visibility, connect interdependent initiatives, identify cross-portfolio dependencies and risks, facilitate decision-making, and support effective execution and follow-through across organizational boundaries, while helping ensure the collective portfolio remains aligned to business and portfolio priorities and intended strategic outcomes.

Working in partnership with PSTS digital leadership, Finance, JJT, DDSAI, business owners, and initiative leads, the role will be accountable for the integrated program-management layer across the portfolio, connecting priorities, plans, dependencies, risks, resource considerations, decisions, governance, and outcomes across the collective body of work. The role will maintain clear accountability with the teams responsible for individual project delivery, technical execution, financial management, and business outcomes.

In addition to the initial PSTS digital focus, the Senior Manager may apply these capabilities to other high-priority SIS and PSTS strategic priorities, operating model changes, portfolio initiatives, and transformation efforts where cross-functional coordination and disciplined execution are critical.

You will be responsible for:

  • Strategic & Portfolio Alignment: Connect PSTS digital, data, AI, and technology priorities and investments to business and portfolio priorities and intended outcomes. Support prioritization and sequencing discussions by providing visibility to strategic alignment, dependencies, resource implications, risks, trade-offs, and portfolio value.
  • Strategic & Digital Program Enablement: Lead integrated program management across PSTS digital, data, AI, and technology priorities, connecting strategic priorities, initiatives, milestones, dependencies, risks, decisions, and execution needs into a cohesive program view.
  • Integrated Planning & Coordination: Develop and maintain integrated program and portfolio plans and facilitate alignment across business owners, digital leadership, Finance, JJT, DDSAI, initiative leads, and other partners. Connect activity across initiatives to provide visibility to overall progress, interdependencies, and execution needs.
  • Programmatic Management & Execution Enablement: Lead the program-management layer across the portfolio, including integrated planning, milestones, critical dependencies, risks, issues, decisions, governance, and escalation. Drive alignment and follow-through across initiatives and work with project and initiative leads to ensure progress against agreed priorities and plans, while preserving their accountability for day-to-day project delivery.
  • Risk, Dependency & Resource Integration: Proactively identify cross-initiative dependencies, resource and capacity constraints, execution barriers, and emerging risks. Facilitate cross-functional resolution where possible and timely escalation when leadership decisions or trade-offs are required.
  • Leadership Decision Enablement: Synthesize complex portfolio and program information into clear insights, options, trade-offs, risks, and recommendations to support leadership decision-making, prioritization, sequencing, and resource discussions. Prepare and support leadership governance forums, facilitate timely decision-making, and drive accountability for follow-through across complex cross-functional priorities.
  • Governance & Portfolio Visibility: Establish fit-for-purpose governance, program reviews, decision pathways, and portfolio-level reporting that provide leaders and stakeholders with meaningful visibility to progress, risks, dependencies, decisions, and outcomes, including portfolio value and alignment to strategic priorities.
  • Change & Business Readiness: Integrate stakeholder engagement, organizational readiness, adoption, and implementation considerations across major initiatives to support effective deployment and sustained business adoption.
  • Outcomes & Continuous Improvement: Connect program activity to intended scientific, business, operational, portfolio, and enterprise outcomes and identify opportunities to strengthen execution, program effectiveness, and ways of working.
  • Strategic Enablement: Apply programmatic leadership and enablement capabilities to other high-priority SIS and PSTS strategic priorities, operating model changes, portfolio initiatives, and transformation efforts as business needs evolve.

Required Qualifications

  • Bachelor's degree in business, science, engineering, technology, project/program management, operations, or a related discipline.
  • A minimum of 8 years of relevant professional experience in program management, portfolio management, business operations, digital transformation, strategic execution, R&D operations, or a related field.
  • Demonstrated experience providing leadership or oversight across complex, cross-functional initiatives or portfolios within a matrixed organization.
  • Strong program management capabilities and demonstrated knowledge of project management disciplines, including integrated planning, dependency management, risk and issue management, governance, and execution oversight.
  • Demonstrated ability to influence, facilitate decisions, and establish accountability across business, scientific, technical, and operational stakeholders without direct authority.
  • Strong risk identification, issue resolution, decision facilitation, and escalation capabilities.
  • Ability to synthesize complex scientific, business, operational, or technical information into clear insights, recommendations, and leadership-level communications.
  • Strong analytical, problem-solving, stakeholder management, facilitation, and communication skills.
  • Demonstrated ability to operate effectively amid ambiguity and changing priorities while maintaining appropriate structure, momentum, and follow-through.

Preferred Qualifications

  • Master's degree, MBA, or other relevant advanced degree.
  • Experience within pharmaceutical, biotechnology, healthcare, life sciences, or R&D environments.
  • Experience supporting digital transformation, data, AI, automation, or technology-enabled business transformation.
  • Experience working across business, scientific, digital, technology, and data science organizations.
  • Experience with portfolio governance, prioritization, strategic planning, organizational change, and business adoption.
  • Familiarity with regulated environments and considerations related to data governance, information security, compliance, or technology controls.
  • Project/program management, Agile, change-management, or comparable certification or training.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

If you are under 18 years of age you (the candidate) may need to obtain the necessary working papers or other documentation required by state law to start the assignment, as well as get a parent's consent for the background check

#LI-Hybrid

The anticipated base pay range for this position is :

$137,000.00 - $235,750.00

Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company's long-term incentive program.

Benefits

  • Vacation -120 hours per calendar year
  • Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado -48 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year
  • Holiday pay, including Floating Holidays -13 days per calendar year
  • Work, Personal and Family Time - up to 40 hours per calendar year
  • Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child
  • Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
  • Caregiver Leave - 80 hours in a 52-week rolling period10 days
  • Volunteer Leave - 32 hours per calendar year
  • Military Spouse Time-Off - 80 hours per calendar year

Please use the following language:

For additional general information on Company benefits, please go to:

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Vacancy posted 4 days ago
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