Scientist, Translational Research Science, Haem R&D

Introduction to role Are you ready to turn innovative translational science into meaningful progress for people living with blood cancers? As a Scientist, within the Translational Research Science Haem R&D team, you will be part of high-caliber team to design and deliver translational assays and data that steer clinical trials, sharpen pre-clinical decisions, and unlock new combinations across indications. Your work will have a special focus on generating impactful data, ensuring our programs move forward with clarity and confidence. In this role, you will shape how we understand tumor biology, minimal residual disease, and resistance mechanisms—translating insights into actions that accelerate our pipeline. You will connect laboratory discovery to clinical strategy by integrating translational scientists with discovery, data science, and clinical teams. Do you thrive at the interface of bench science and patient impact, where meticulous execution meets critical thinking? Accountabilities Reporting to a Sr Scientist/Associate Director, lead hands-on execution of non-clinical and translational experiments focused on hematological tumor biology. Tasks include assessing target expression post-treatment, applying reverse translation to reveal resistance mechanisms, and informing new combination strategies across multiple indications. Assay development for hematologic Malignancies: Build and validate translational assays supporting programs across different heme indications to broaden portfolio impact. Scientific communication: write technical reports, SOPs and present data to stakeholders, that clearly convey methodologies, findings, and implications for development. Quality and compliance: Perform all duties in compliance with internal SOPs and external regulations, embedding standard methodologies and reproducibility in every study. Required technical skills and experience At least 2 years of research experience in academic or industry setting. Previous translational research experience in hematological malignancies is highly desired. Proficiency in cell culture techniques, immune-based assays (Western Blot, ELISAs, Flow Cytometry, Luminex/MSD), gene expression (NGS, qPCR and/or Quantigene) and data analysis platforms (e.g. FlowJo, Prism, R, OMIQ) is required. Experience writing technical reports and SOPs is required. Experience with biospecimen managing and handling (sample tracking software’s, liquid nitrogen storage systems) and general lab management (e.g. supplies ordering and inventory) Excellent organizational and interpersonal skills for cross-functional interactions. Dedication to carrying out all duties according to internal SOPs and external regulations. When we put unexpected teams in the same room, we ignite bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world! Why AstraZeneca Here, curiosity powers progress—teams are encouraged to follow the science, question assumptions, and push boundaries to transform molecules into medicines that change clinical practice. With a robust pipeline across multiple cancer indications and a history of bringing new therapies to patients, we combine groundbreaking technology with an entrepreneurial spirit and a collaborative community that spans leading medical centers worldwide. We value kindness alongside ambition, unite teams to unlock ambitious thinking, and back critical, high-quality science with sustained investment so your contributions translate into real impact for patients. Call to Action Bring your translational research experience to a place where science moves fast and your work steers pivotal decisions—step into this Associate Director role and help shape the future of hematology today! The annual base pay for this position ranges from $92,252.00 - $138,378.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted09-Jul-2026Closing Date07-Aug-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.SummaryLocation: US - Cambridge Kendall SQ - MAType: Full time