Clinical Trial Manager

About Ossium

Ossium's mission is to improve the health, vitality, and longevity of human beings through bioengineering. We develop, manufacture, and bank cell therapy products that apply the power of stem cell science to revolutionize treatment for patients with blood, immune, and orthopedic diseases. At Ossium, we empower our employees, maintain the highest standards of operational excellence, and are a force for good.

About the Job

We are hiring a Clinical Trial Manager to support the successful execution of our clinical trials and operations. In this role, you'll take ownership of the day-to-day tactical management of ongoing studies, ensuring seamless trial implementation and monitoring.

You'll play a key role in launching our PRESERVE II clinical trial, the long-term follow-up of PRESERVE I, and our HOPE expanded access program. This position is ideal for someone who thrives in a hands-on, fast-paced environment-someone eager to collaborate across teams and coordinate with internal partners, CROs, and external vendors to deliver excellence in every aspect of our trials.

This role reports to the Senior Director, Clinical Operations.
Required Qualifications

• Degree in Life Sciences & industry-sponsored clinical trial experience:
  • BS & 3+ years
  • MS/MPH & 1+ years
• Experience with or managing CROs; either from within a CRO in a major role, or from a sponsor-side biotech or pharmaceutical company at the Clinical Trial Manager or Clinical Project Manager level
• Strong written and verbal communication skills, with the ability to share complex information clearly and effectively across teams and stakeholders
• Exceptional organizational and time management abilities, with comfort operating in a fast-moving, dynamic startup environment
• Proven capacity to manage multiple priorities simultaneously, maintaining accuracy and attention to detail
• A collaborative, execution-oriented mindset with the ability to build alignment and drive progress across cross-functional teams
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Ability to travel as needed (10% - 15%)
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• CRA/site coordinator experience
• Trial experiences in full life cycle of clinical trial
• Experience in cell therapy
• Experience in rare disease; hematologic malignancies (specifically bone marrow transplant)

Key Responsibilities

• Serve as the primary liaison with the CRO supporting PRESERVE II study activities, ensuring alignment on timelines and deliverables
• Review and contribute clinical operations input to key study documents including protocols, investigator brochures, regulatory submissions, clinical study reports, and operational plans developed by CRO partners
• Oversee site feasibility and capability assessments in close collaboration with the CRO and cross-functional teams
• Support additional clinical programs and studies as assigned, working closely with the Senior Director, Clinical Operations to meet strategic and operational objectives
• Partner with cross-functional groups, including Transplant Operations, Regulatory Affairs, and other stakeholders to ensure seamless coordination and successful trial execution
• Help lead and monitor trial execution to ensure compliance with ICH/GCP guidelines, applicable regulations, and company policies
• Organize and lead internal clinical project meetings, fostering collaboration and keeping teams aligned on goals and progress

In your first six months some projects you'll work on include:

• Driving completion of critical milestones for the start of PRESERVE II clinical trial
• Supporting the active PRESERVE I study long term follow up
• Collaborating internally with other functions for clinical study implementation
• Conducting clinical project team meetings

This position has a salary range of $145,000 - $165,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate's starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

Ossium Health provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, protected veteran status, sexual orientation, gender identity, gender expression, or any other protected characteristic. Our Equal Employment Opportunity Policy Statement and the Know Your Rights: Workplace Discrimination is Illegal Poster reaffirm this commitment. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

If reasonable accommodation is needed, please contact our People Team at View email address on click.appcast.io or View phone number on click.appcast.io. Ossium Health complies with federal and state disability laws and makes reasonable accommodations for applicants and candidates with disabilities.

Principals / direct applicants only please. Recruiters, please do not contact this job poster.


Equal Opportunity Employer/Veterans/Disabled