Senior Director, Engineering and Technology (Holly Springs)
$173.95k - $323.05kF. Hoffmann-La Roche AG
Overview Head of Engineering at Holly Springs, North Carolina, responsible for leading the engineering, science, and technology strategy shaping a state‑of‑the‑art, high‑volume drug product manufacturing facility. The role drives capital execution, asset life‑cycle management, maintenance & reliability, and continuous improvement across the new green‑field build and its ongoing operations. Responsibilities Develop and execute the overall engineering, science, and technology strategy at Holly Springs. Lead equipment, facility and utility selection, qualification, and operational start‑up of the green‑field assets. Drive the site maintenance & reliability program, capital execution, asset life‑cycle management and world‑class asset management. Establish a world‑class asset maintenance management system and oversee all site facility services. Build and manage a high‑performing team, fostering continuous improvement and innovation. Collaborate with global functions, suppliers, local expertise and other Roche sites to deliver technical excellence. Lead the Site Leadership Team, report directly to the Site Head, and implement lean and agile ways of working. Ensure GMP compliance, continuous improvement, and achievement of long‑term goals. Manage performance and development of the Engineering Unit and build a robust talent pipeline and succession plans. Qualifications Bachelor’s degree in an engineering discipline (graduate degree or MBA preferred). 15+ years of pharmaceutical industry experience, with 6+ years of people and project management and 4+ years of facilities management, engineering, or related experience. Proven experience leading maintenance strategy and world‑class maintenance programs. Strong leadership, collaboration, and cross‑functional team skills in a matrix organization. Deep understanding of manufacturing and business processes at a site and the ability to navigate the network of opportunities and challenges. Assertiveness, continuous improvement mindset, and a history of coaching and implementing lean and agile approaches. Excellent written and verbal communication skills in English. Salary Projected range: $173,950 – $323,050 (based on location; actual pay depends on experience, level, qualifications, geography, and other permissible factors). Equal Employment Opportunity Statement Genentech is an equal‑opportunity employer. We employ, promote, and otherwise treat employees and applicants on the basis of merit, qualifications, and competence. The company policy prohibits unlawful discrimination on the basis of veteran status, disability status, or any other protected class, consistent with all applicable federal, state, and local laws. If you require accommodation during the application process, please contact us to complete the Accommodations for Applicants form. #J-18808-Ljbffr F. Hoffmann-La Roche AG
$78.9k - $146.5k
...new large‑volume, low‑cost drug product manufacturing site will be built in Holly Springs, North Carolina. ITOT will own and operate the manufacturing technology stack there. The SrMES Engineer will participate in greenfield project execution and later support operations...SeniorLocal areaWorldwideRelocation$161k - $299k
Welcome to Holly Springs, North Carolina— home to Roche/Genentech's largest... ...-up where next-generation technology, high-performing teams and... .... The Opportunity: The Sr Director, Head of Material Management... ...logistics, science, business, engineering or other relevant discipline...SeniorFull timeTemporary workWork experience placementLocal areaRelocation packageFlexible hours$95.2k - $176.8k
...manufacturing for Roche. A new manufacturing site is being built in Holly Springs, North Carolina, focused on large volume low‑cost drug... ...manufacturing. This role is a Principal Instrumentation & Controls Plant Engineer, the site’s highest-level technical subject matter expert in...SuggestedLocal areaRelocation package$173.95k - $323.05k
F. Hoffmann-La Roche AG is seeking a Head of Engineering in South San Francisco to lead the engineering, science, and technology strategy for a high‑volume drug product manufacturing facility. You will oversee the entire lifecycle from capital execution to continuous improvement...Senior$81.4k - $151.2k
...equipment including procedures and training; support FATs for Packaging Equipment; flex to support other Holly Springs assets; partner and collaborate with Engineering, MSAT, Quality, Supply Chain, Technical Development, Regulatory, CMO, and Strategy; transition from...SuggestedFull timeLocal areaRemote workFlexible hoursShift work$81.4k - $151.2k
..., PTM will construct a new manufacturing site in the U.S. in Holly Spring, North Carolina. The new site will focus on large volume low... ...Assembly Equipment; work as part of the User Team; collaborate with Engineering, MSAT, Quality, Supply Chain, Technical Development,...Local areaRemote workFlexible hoursShift work- Turbohire Technologies Pvt Ltd is seeking a seasoned Java Developer with at least 8 years of experience in designing and maintaining Java... ...web services, developing applications using frameworks such as Spring Boot and Hibernate, and implementing both front-end and back-...Senior
$200k - $250k
A leading adventure sports technology company is seeking an entrepreneurial-minded engineering leader in San Francisco. This role involves overseeing product design and development for outdoor communication devices. The ideal candidate has over 10 years of experience in...Senior- DocuSign, Inc. in San Francisco is seeking an Application Engineering Leader to transform its business technology landscape through software and AI solutions. This hybrid role involves leading engineering teams, driving technology innovation, and ensuring alignment with...Senior
$200k - $280k
...Director of Engineering Job type: Full Time · Department: Technology · Work type: Hybrid · USD 200,000-280,000 / year Charlotte, North Carolina, United States; San... ...Technical Stack Languages/Frameworks: Java, Kotlin, Spring Boot. Infrastructure: AWS (EKS, S3, SNS, SQS,...Full time$94k - $174.6k
Position Overview Senior Quality Compliance Specialist - responsible for designing and implementing site‑wide Quality Risk Management, Data Integrity, and Change Control initiatives, ensuring compliance with global regulations and Roche internal standards. What You’ll...SeniorLocal areaRelocation package- A leading technology company in San Francisco is looking for a Senior Engineering Manager to oversee the Model Serving product. This role involves leading a high-performing engineering team, defining the product roadmap, and ensuring the product meets rigorous performance...Senior
- A tech-driven company in San Francisco seeks a Senior Engineering Manager to lead and scale an engineering team working on an innovative... ...engineering teams and a strong technical background in relevant technologies. This position offers a competitive salary and equity in a...Senior
$300 per month
...energy and intelligence. We’re crafting the engine that powers a world where people can... ...part of the AI revolution with sustainable technology at Crusoe. Here, you'll drive meaningful... ..., transformative cloud infrastructure. Senior Engineering Manager, Compute San...SeniorTemporary work$261k - $326k
A technology company specializing in AI infrastructure is seeking a Principal Engineer to enhance reliability and scalability of cloud systems. This role demands over 15 years of experience in production engineering or related fields and involves setting technical directions...Senior- ...Join This Team? This isn’t just another engineering firm—it’s a place where innovators, mentors... ...Access to advanced, cutting‑edge technology Strong, collaborative relationships Team... ...Resilient Transformative The Opportunity: Senior Electrical Design Engineer The Senior...Senior
$94k - $174.6k
Overview Welcome to Holly Springs, North Carolina—home to Roche/Genentech's largest-ever investment: a $2B greenfield start-up where next-generation technology, high-performing teams and Operational Excellence converge to create the global standard for high-volume, highly...SeniorLocal areaRelocation- A technology company in San Francisco is looking for a Senior Engineering Manager, Data Plane Systems to lead high-performance SDN data planes. This hands-on leadership role requires at least 10 years of experience in networking or systems engineering. Responsibilities...Senior
$180k - $220k
...things move for businesses, governments and consumers. The technology is complex but the idea is simple: a teleportation service that... ...About You and the Role Zipline is hiring a Mechanical Test Engineering Manager that is excited to lead the team responsible for testing...SeniorLocal area- A leading technology firm in San Francisco seeks a Senior Engineering Manager to lead a team focused on high-performance computing for AI. The ideal candidate will have over 5 years of experience in engineering management and a background in systems programming. Responsibilities...Senior
$160k - $190k
...business decisions. Gather requirements from potential customers, engineering and construction companies, equipment manufacturers,... ...retire risks and use SB Energy’s Innovation Center for real‑world technology demonstrations. Assist first‑of‑a‑kind deployment into...SeniorWork at officeRemote workFlexible hours- ...Senior Engineering Manager, Lifecycle Management About Nue Nue is a fast-growing revenue lifecycle platform that manages the entire revenue... ...Components (LWC), SOQL, Flows, managed packages Backend: Java (Spring Boot), Node.js, REST APIs, GraphQL Frontend: React 16, TypeScript...Senior
$147.8k - $274.4k
...Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models... ...We are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation...SeniorLocal areaWorldwideRelocation package- ...A leading battery technology company in South San Francisco seeks a Mechanical Engineer specializing in EV battery systems. This role involves leading design and validation efforts, evaluating new technologies, and working within a dynamic team. Candidates should have...Senior
- ...Senior Director – Applications Engineering (Photonic Solutions) Full Time Onsite in the Bay Area, CA Highly flexible and Highly competitive Compensation package (open to discussion for the right candidate) Up to 25-30% travel Working with top-tier hyperscale...SeniorFull timeFlexible hours
- POSITION TITLE:Senior Project Manager (Civil/Structural Engineering) Hinman Consulting Engineers, Inc. provides advice and solutions to protect people, operations... ...US General Services Administration, a Fortune 50 technology company, and the State of California. Mission...SeniorFull timeContract workWork at officeWorldwideFlexible hours
$142.4k - $224.1k
Overview We are hiring an Associate Director, Engineering within Biologics External Manufacturing Technology. The role serves as the key technical leader interfacing with external partners to manage technology transfers, commercial supply, and partner integration. The...For contractors- Merck & Co. is hiring an Associate Director, Engineering in South San Francisco. This role focuses on managing technology transfers and collaborating with external partners to ensure manufacturing success. The ideal candidate will possess a bachelor’s degree in engineering...Relocation
- ...Salesforce Platform, Real-time Communication technologies and AI to make a direct impact on... ...Yes, you need to check out the Software Engineer openings on the Agentforce team! Agentforce... ...Python, Java/J2EE technologies such as Spring, Spring Boot, Hibernate and EJB...SeniorFlexible hours
- ...a mission to redefine the way businesses‑of‑one work. Our technology and team of trusted advisors help members achieve financial... ...passion, not paperwork. About the role We’re hiring a Director of Engineering to build and evolve the core product experiences that power...Self employmentWork at officeRemote workFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Director, Engineering and Technology (Holly Springs). Be the first to apply!
- senior director engineering South San Francisco, CA
- engineering director South San Francisco, CA
- principal engineer South San Francisco, CA
- director software engineering South San Francisco, CA
- general engineer South San Francisco, CA
- senior chief engineer South San Francisco, CA
- principal developer South San Francisco, CA
- senior principal engineer South San Francisco, CA
- data center chief engineer South San Francisco, CA
- senior civil engineer project manager South San Francisco, CA


