Sr. Manager, Accounts Payable

CareDx is a leading precision medicine diagnostics company advancing care in transplant, specialty oncology, and cell therapy. Through our innovative portfolio of molecular diagnostics, digital health solutions, AI-powered data and analytics, and patient support services, we partner with healthcare providers, patients, and biopharma organizations to help inform clinical decision-making and improve patient outcomes.

At CareDx, every employee has the opportunity to contribute to innovations that help transform patient care and improve lives.

The Sr. Manager, Accounts Payable, is a highly motivated and experienced individual who leads our Accounts Payable (AP) function. This role is responsible for overseeing the end-to-end AP process, ensuring timely and accurate payment of invoices, strengthening internal controls, and driving operational excellence across the cycle.

The ideal candidate is both a strong operator and a process leader—capable of managing a team, improving systems and workflows, and maintaining a robust, audit-ready control environment. This role will partner closely with Accounting, Procurement, Treasury, and internal stakeholders to deliver efficient, scalable, and compliant AP operations. Ideally looking for candidates either in Chicago, Illinois or Milwaukee, WI.

Responsibilities:
• Lead, mentor, and develop a team of AP professionals
• Establish clear roles, responsibilities, and manage performance expectations
• Foster a high-performing, service-oriented culture focused on responsiveness and accuracy
• Manage team capacity, workload prioritization, and continuous skill development
• Ensure timely and accurate processing of invoices and payments in accordance with company policies and SLAs
• Manage payment runs and ensure compliance with approval and authorization requirements
• Monitor AP aging, identify bottlenecks, and drive resolution of outstanding items
• Build and maintain strong relationships with vendors and internal stakeholders
• Ensure timely resolution of vendor inquiries, payment issues, and disputes
• Own AP process requirements and partner with Finance Systems / IT to optimize workflows within Coupa and NetSuite
• Drive initiatives to increase electronic payments and reduce manual processes
• Support supplier portal adoption and vendor onboarding enablement
• Oversee key fraud prevention controls, including vendor validation and payment verification
• Ensure compliance with SOX requirements, including segregation of duties and approval workflows
• Prepare for and support internal and external audits, including walkthroughs
• Identify control gaps and lead remediation efforts
• Own AP-related close activities (subledger reconciliations, aging review)
• Provide reporting and insights into AP performance and trend
• Partner with Treasury to support cash flow planning and optimize payment timing
• Standardize and document AP processes, policies, and procedures
• Lead continuous improvement initiatives to enhance efficiency, scalability, and accuracy

Minimum Education, Experience, & Specialized Knowledge (Required):
• Bachelor’s degree in Accounting, Finance, or related field
• 8+ years of progressive Accounts Payable experience, including 3+ years in a leadership role
• Strong understanding of AP processes, P2P workflows, and accounting principles
• Experience operating in a SOX-compliant environment
• Proficiency with ERP systems (e.g., NetSuite) and AP automation tools (e.g., Coupa)
• Strong analytical, problem-solving, and organizational skills
• Excellent communication and stakeholder management skills
• Experience working in a high-growth or transforming organization
• Track record of implementing process improvements or system enhancements
• Experience leading remote or distributed teams

Additional Details:

Every individual at CareDx has a direct impact on our collective mission to improve the lives of organ transplant patients worldwide. We believe in taking great care of our people, so they take even greater care of our patients.

Our competitive Total Rewards package for US Employees includes:

• Competitive base salary and incentive compensation
• Health and welfare benefits, including a gym reimbursement program
• 401(k) savings plan match
• Employee Stock Purchase Plan
• Pre-tax commuter benefits
• And more!
• Please refer to our page to view detailed benefits at

In addition, we have a Living Donor Employee Recovery Policy that allows up to 30 days of paid leave annually to a full-time employee who makes the selfless act of donating an organ or bone marrow.

With products that are making a difference in the lives of transplant patients today and a promising pipeline for the future, it’s an exciting time to be part of the CareDx team. Join us in partnering with transplant patients to transform our future together.

CareDx, Inc. is an Equal Opportunity Employer-vets/disabled, and participates in the E-Verify program. By proceeding with our application and submitting your information, you acknowledge that you have read our U.S. Personnel Privacy Notice and consent to receive email communication from CareDx. Certain jurisdictions require notice of how we use and protect your personal information. For more information, please read our Privacy Policy

The U.S. EEO posters are available here.

Note: We do not accept resumes from headhunters, placement agencies, or other suppliers that have not signed a formal agreement with us.

#LI-Remote

This is the anticipated base salary range in the United States. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

Remote: US only roles

$131,000—$170,000 USD