Associate Scientist: Downstream Process Development

Associate Scientist - Contract - Cambridge, MA Passionate about analytical chemistry and process development? Join a team advancing cutting-edge oligonucleotide manufacturing technologies. Proclinical is seeking an Associate Scientist II will join the CMC - DS Process Development Group at our client's facility in the US. Primary Responsibilities The successful candidate will be supporting process development efforts to incorporate novel chemistries into the manufacturing platform. Skills & Requirements Required: BS in Chemistry or Chemical Engineering Process development experience/background Strong analytical chemistry background and hands-on laboratory experience Chemistry background with experience running analytical testing, particularly LC/HPLC Understanding of analytical techniques such as pH, Osmolality, Conductivity, HPLC, and LC-MS Strong laboratory documentation and record-keeping practices Knowledge of oligonucleotide manufacturing, including: Phosphoramidite chemistry, Chromatography, and Ultrafiltration Experience with relevant analytical testing software, e.g., Agilent and UNICORN laboratory software The Associate Scientist's responsibilities will be: Support oligonucleotide synthesis method development, optimization, and scale-up Support downstream processing method development Execute in-process analytical testing Partner with research and process scientists to develop robust processes for novel chemistries Maintain strong laboratory documentation and record-keeping Maintain a safe, clean, and orderly laboratory environment Assist with routine laboratory and equipment maintenance By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - #J-18808-Ljbffr Proclinical Group