Portfolio Pathologist (Anatomic)

Senior Principal Scientist or Associate Director

In this key role you will provide pathology subject matter expertise across drug discovery and development programs throughout the nonclinical and clinical development lifecycle, and/or contributes to department aligned technology development. You will also apply deep scientific judgment to assess the impact, limitations, and value of pathology data to advance projects, inform human risk assessment, and support Novartis portfolio strategy. You will have the opportunity to collaborate broadly across project teams, therapeutic areas, modalities, and external partners while maintaining compliance with Novartis policies, SOPs, GxP, One Quality, and health and safety requirements.

Key Responsibilities:

• Generate, evaluate, and interpret GLP and non-GLP pathology data for assigned studies, including determination of adversity where appropriate.
• Conduct and/or support postmortem phases of toxicology studies, including pathology peer and scientific review.
• Contribute to integrated nonclinical data analyses, interpretation, human risk assessment, and high-quality reporting.
• Support regulatory submissions through preparation and review of pathology related documentation.
• Serve as a pathology contributor or early project team representative for preclinical safety.
• Participate in nonclinical study design, protocol writing, and review.
• Monitor and review pathology procedures and data generated by CROs and external partners.
• Provide scientific and technical interpretation using expertise in clinical pathology, histopathology, histochemistry, morphology, image analysis, transcriptomics, electron microscopy, and related techniques.
• Identify and contribute to novel projects or emerging scientific/technical areas aligned with departmental strategy.
• Maintain current knowledge of scientific advances, technologies, and methodologies.
• Collaborate across therapeutic areas and modalities; identify key connection points to enable project progression.

Essential Requirements:

• Education: DVM (or equivalent, e.g., BVSc)
• Graduate training in pathology
• Preferred candidate will also have a PhD in a relevant biological or toxicologic field and 2 plus years of experience in toxicologic pathology; 5 plus years to be considered at the Associate Director level
• Pathology board certification (e.g., DACVP, ECVP, FRCPath)

To be considered at the Associate Director level you will also have:

• Demonstrated team leadership
• Ability to supervise direct and develop others
• Experience leading programs, platforms, or initiatives

This is a dual posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered.

The salary for this position is expected to range between:

Senior Principal Scientist I: $176,400 and $327,600 per year.

Associate Director: $185,500 and $344,500 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to View email address on click.appcast.io or call View phone number on click.appcast.io and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Skills Desired

Analytical Thinking, Bioinformatics, Clinical Data Management, Collaboration, Communication Skills, Critical Thinking, Data Analysis, Detail-Oriented, Drug Discovery, Ethics, Laboratory, Lifesciences, Management, Medical Research, Organization, Problem Solving Skills, Regulatory Compliance, Reports Writing, Team Management, Technical Skills, Time Management Skills, Toxicology, Training, Waterfall Model