Scientist II, Antisense/siRNA and Peptide Purification
$56.25 - $75.48 per hourBiogen Idec
About This RoleAt Biogen, we are advancing science to transform patients’ lives. We are seeking a highly motivated Scientist II to join our Technical Development team in Cambridge, MA, focused on oligonucleotide (Antisense/siRNA) and Peptide Purification. This is an exciting opportunity to design and develop robust, scalable purification processes that directly impact clinical and commercial therapeutics. You will play a key role in advancing next-generation modalities by bridging early development with manufacturing, working in a highly collaborative, cross-functional environment. Your work will contribute to building state-of-the-art platform processes that improve product quality, scalability, and efficiently enabling delivery of innovative therapies to patients.Who We Are: We are a team of chemists and chemical engineers engaged in the design of innovative processes which supply new medicines to patients. We focus on developing safe, economical, sustainable, cost-effective, and robust processes to support clinical trials and the launch of new medicines across various drug modalities. We are driven by first principles science, data-driven decision-making, and collaborative teamwork.What You’ll Do:Design, develop, and scale purification processes across development stages (early development through commercial)Apply data-driven approaches (e.g., DoE) to characterize processes and define robust control strategiesLead or support technology transfer of processes into GMP manufacturingTroubleshoot process challenges and drive continuous improvement in process performanceCollaborate with Manufacturing, Analytical, Quality, Non-Clinical, and Regulatory teams to enable program advancementAuthor technical reports and contribute to CMC sections of regulatory filings and respond to agency questions.Who You Are: You are a hands-on purification scientist who thrives in a dynamic, team-oriented environment. You possess strong analytical skills, and a keen ability to apply statistical analysis to complex data. You have a natural curiosity and a passion for process development. Your technical writing and communication skills are excellent, enabling you to effectively present technical data and contribute to regulatory documentation.Required Skills:Ph.D. degree in chemical engineering, chemistry, or a related science with 0-3 years of experienceMaster’s degree in chemical engineering, chemistry, or a related science with 4+ years of experience in pharmaceutical or biotech settings.Bachelor’s degree in chemical engineering, chemistry, or a related science with 6+ years of relevant experience in pharmaceutical or biotech settings.Experience in purification process development, preferably in an industrial environment.Strong analytical skills and statistical analysis expertise.Proficiency in technical writing and presenting technical data.Preferred Skills:• Experience in developing processes for oligonucleotides, peptides, and/or proteins.• Familiarity with GMP manufacturing processes.• Collaborative mindset with experience working in cross-functional teams.Job Level: ManagementAdditional InformationThe base compensation range for this role is: $117,000.00-$157,000.00Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance. In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:Medical, Dental, Vision, & Life insurancesFitness & Wellness programs including a fitness reimbursement Short- and Long-Term Disability insuranceA minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)Up to 12 company paid holidays + 3 paid days off for Personal Significance 80 hours of sick time per calendar yearPaid Maternity and Parental Leave benefit 401(k) program participation with company matched contributionsEmployee stock purchase plan Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participationWhy Biogen?We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.SummaryLocation: Cambridge, MAType: Full time
$117k - $157k
...to transform patients’ lives. We are seeking a highly motivated Scientist II to join our Technical Development team in Cambridge, MA, focused on oligonucleotide (Antisense/siRNA) and Peptide Purification. This is an exciting opportunity to design and develop robust, scalable...SuggestedFull timeTemporary workLocal area$108.5k - $201.5k
...lives around the world. As a Principal Scientist I or II, Oligonucleotide Chemistry and... ...DescriptionKey ResponsibilitiesLead synthesis, purification, characterization, and analysis of... ...small interfering ribonucleic acid and antisense oligonucleotides.Excellent collaboration...SuggestedFull timeLocal areaWorldwideFlexible hours$117k - $157k
...innovative therapies that transform patients’ lives. We are seeking a Scientist II to join our Analytical Development team as a Liquid... ...programs involving emerging modalities (e.g., oligonucleotides and peptides). Who You Are: You are enthusiastic about tackling complex...SuggestedFull timeTemporary workLocal area$66.8k - $124k
...Cambridge, MA is seeking a highly motivated Research Scientist with experience in production and purification of viral vectors to join our team. In this role, you... ...Internal Job Title: Research Scientist I/II Position Location :Cambridge, MA, onsite ** This...SuggestedRelocation package$66.8k - $124k
...Internal Job Title: Research Scientist I/II Position Location: Cambridge, MA, onsite Key Responsibilities: Hands-on execution of lentiviral vector purification activities, including clarification, chromatography, and TFF. Execute molecular- and cell-based analytical methods...Suggested$126k - $234k
Job Description Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal ScientistLocation: Cambridge, MANovartis is... ...strictly required. Experience with oligonucleotide therapeutics (siRNA, ASO, PMO, etc.) and/or related experience with antibody-drug...Full time$67.6k - $101.4k
...Overview We are seeking a talented candidate to fill an Associate Scientist II position within Alnylam’s Research department. This position... ...rodent disease models, evaluation of small interfering RNAs (siRNAs) in wild-type animals, and conducting the associated in vitro...Full timeTemporary workLocal areaFlexible hours- Job Title Bench Scientist - II Location Cambridge, MA 02140 Duration 2 Years (Possibility of extension depending upon business requirements... ..., restriction digestions, gel electrophoresis, bead-based purification, and related molecular biology workflows. Support next-...
- ...genetic medicines. It's team of driven scientists is making a mark in delivery of oligonucleotides... ...and new collaborations. As a Scientist II in Protein Science - Conjugation, you'll... ...builds its conjugation chemistry and purification capabilities, this role gives you real...Work at office
- Novartis in Cambridge, MA is seeking a Research Scientist I/II focused on lentiviral vector purification and analytics to support CAR-T programs. This lab-based role requires hands-on purification (clarification, chromatography, TFF) and analytical testing to characterize...
- Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA, is seeking a Research Scientist I/II focused on lentiviral vector purification and analytics. The role spans purification and analytical workflows to support next-generation CAR-T programs, with hands-...
- Alnylam Pharmaceuticals seeks an Associate Scientist II for the RNAi Discovery team in Cambridge, MA. The role focuses on QC of single stranded RNA using analytical techniques and formulation of siRNA test articles to support multiple therapeutic areas. The position is...
$66.8k - $124k
Summary Job Title: Research Scientist I or II, Oligonucleotide Chemistry #LI-Onsite Location: Cambridge, USA Relocation... ...techniques. Develop and optimize synthesis, purification, and analytical methods to improve performance and reproducibility...Local areaRelocation packageFlexible hours$125k - $170k
...Does it excite you to be the go-to purification expert delivering high-purity samples for... ...colleague. Your new position As a Scientist or Senior Scientist in Protein Purification... ...purification of recombinant proteins, peptides, and their bioconjugates (e.g., ADCs,...Full time$67.6k - $101.4k
...individual to join our Annealing and Testing group as an Associate Scientist II. The Annealing and Testing group is responsible for the... ...group is responsible for formulating high quality test articles (siRNA) to support research efforts across multiple therapeutic areas...Full timeTemporary workWork experience placementLocal areaFlexible hours- Alnylam Pharmaceuticals is seeking an Associate Scientist II to support our RNAi therapeutic programs within the Research department. You... ...execute, and analyze studies in rodent disease models, evaluate siRNAs in animals, and perform in vitro assays such as qPCR, ELISA,...
$150k - $170k
...OverviewRepertoire Immune Medicines is seeking a Deep Learning Scientist II to join the Artificial Immune Intelligence Team to accelerate... ...proprietary datasets about T cell receptors interacting with peptide-MHC complexes.Key Responsibilities Develop novel deep learning...Temporary workWork experience placementFlexible hours$40 - $42.7 per hour
job summary: Accelerate your research career as a Bench Scientist - II with a top-tier biopharmaceutical leader in Cambridge, MA. Located... ...-based role allows you to perform vital recombinant protein purification, labeling, and characterization work. Work alongside a...Hourly payContract workTemporary workWork experience placement- Job Description Associate Scientist II Cambridge,MA 12 months contract Job Summary The successful candidate will be a part of the CMC - DS Process Development Group, responsible for the process development to incorporate Client chemistries into our manufacturing platform...Contract work
$140k - $196k
...are seeking a creative, motivated Computational Protein Design Scientist to join our Model-Driven Design team at Generate:Biomedicines.... ...modalities such as antibodies, mini-proteins, VHHs, peptides, or enzymes, and an eagerness to deepen expertise across these...Work at officeShift work$100k - $140k
...Karczewski lab in the Analytic and Translational Genetics Unit (ATGU) at the Broad Institute and MGH. We are looking for a computational scientist II with experience in large scale genomic analysis (e.g. gnomAD, multi-phenotype GWAS/RVAS). At ATGU, we build and analyze large-...Full timeLocal areaFlexible hours$119.7k - $222.3k
Job Description SummaryLocation: Cambridge MAInternal: Principal Scientist I/IILI#-HybridThe individual will provide scientific and... ...Scientist I: $119,700 and $222,300 per year.Principal Scientist II: $126,000 and $234,000 per year.The final salary offered is determined...Permanent employmentFull time- Soufflé Therapeutics in Watertown, MA is seeking an Associate Scientist to drive protein conjugation and purification, generating material for in vitro and in vivo studies. You'll work hands-on in a fast-paced biotech environment. This onsite role emphasizes developing...
- Spectraforce Technologies in Cambridge, MA is seeking a Bench Scientist II to join our research team. The role focuses on bench-based antibody discovery, performing routine and advanced molecular biology workflows, and contributing to technology development. You will collaborate...
- Pace® Labs in Cambridge, MA seeks a Scientist to perform advanced analytical development with hands-on operation of High-Resolution LC-MS. You will develop and optimize HPLC and MS-based methods for siRNA identification, characterization, and impurity profiling of molecules...
- Pace® Analytical Services is seeking a Scientist to perform advanced analytical development focused on High-Resolution LC-MS operations and method development for siRNA and related materials. You will optimize HPLC and MS-based methods, support impurity profiling, and contribute...
$140k - $155k
JOB TITLE: Scientist II, Analytical Development LOCATION: Cambridge, MA SALARY RANGE: $140,000 to $155,000 ABOUT THE POSITION Aurion Biotech is seeking a highly motivated Scientist II, Analytical Development in Cambridge, MA. This position will serve as an integral...Work at officeDay shift$36 - $41.82 per hour
...Job Description Job Description Job Title : Bench Scientist II Location : Cambridge, MA Type: Contract Compensation : $3... ...candidates should have a Bachelors degree with 1-2 years protein purification experience. Responsibilities Responsible for purifying...Contract workLocal area$119.7k - $222.3k
...in a lead role overseeing ADME/DMPK project strategy in clinical development, or in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered for Senior Principal Scientist.Extensive and in-depth knowledge of pharmacokinetics including...Full time- ...using appropriate bioinformatics tools. Collaborate with data scientists; contribute to reports and internal presentations. Work with... ...techniques including PCR, qRT-PCR, enzymatic reactions, DNA/RNA purification and manipulation. Experience troubleshooting and optimizing...Local areaRemote work
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