Sr. Dir., Strategic Technology Initiatives Lead

ROLE SUMMARYWe are seeking a Senior Director, Strategic Technology Initiatives Lead to lead and connect Pfizer’s most important strategic technology initiatives with our eight Digital Core Platforms. This leader will oversee a team of Senior Technical Architects and own the connected strategy that ensures high-priority, Executive Leadership Team (ELT)-level AI programs are designed, aligned, and delivered as a coherent whole across the platform landscape.The role is accountable for connecting the technical strategy of individual initiatives into one coherent direction, ensuring each program reinforces the eight Digital Core Platforms rather than diverging from them. Working with senior business and Digital leaders, this leader sets priorities across initiatives, resolves cross-program trade-offs, and ensures the right architects and technical talent are aligned to the most important outcomes.This position requires a senior leader with strong leadership, communication, and organizational skills who can operate at the intersection of strategy, architecture, platform alignment, and organizational leadership. The Senior Director will create clarity from complexity, orchestrate work across many initiatives and teams, develop senior technical talent, and establish a practical, connected strategy that helps Pfizer deliver faster, safer, and more reusable digital capabilities at global scale.ROLE RESPONSIBILITIESConnected Technology Strategy: Own the connected technology strategy across the strategic technology initiatives, ensuring each initiative aligns to and strengthens the eight Digital Core Platforms and Pfizer’s enterprise architecture standards.Platform Alignment and Reuse: Ensure the strategic initiatives make deliberate, reusable use of the eight Digital Core Platforms, driving consistency, reuse, and clean integration rather than duplicated or divergent solutions.ELT-Level Initiative Leadership: Lead the technical strategy and senior stakeholder alignment for key Executive Leadership Team (ELT)-level AI programs, translating ambiguous enterprise priorities into a coordinated set of initiatives with clear owners, delivery models, and measurable outcomes.Architect Team Leadership: Oversee, lead, and develop a team of Senior Technical Architects, setting direction, balancing workload across initiatives, and ensuring consistent architecture quality and standards across the portfolio.AI-Enabled Delivery: Define how AI, automation, and modern engineering practices are responsibly applied across the initiatives to increase speed, improve quality, strengthen decision-making, and maintain appropriate governance and verification.Leadership, Communication, and Organization: Provide clear leadership and set direction with strong, structured communication; organize and coordinate work across many initiatives, architects, and stakeholders; and build a high-performing, inclusive team culture of accountability and continuous learning.Governance and Delivery Assurance: Establish expectations for reliability, security, documentation, and operational excellence across the initiatives, and provide the governance and reporting that keep senior leaders informed and the portfolio on track.ROLE BEHAVIOURSDon't Lose Your Curiosity: Fosters a culture of curiosity and continuous learning across the initiatives and architect team; sponsors experimentation and cross-initiative learning; brings emerging technologies and outside-in perspectives into the connected strategySet an example for your team: Consistently demonstrate a clear vision, positive energy, and exemplary leadership that motivate the architect team and initiative stakeholders to strive for their highest potentialOwn the Outcome: Sets clear accountability standards focused on business impact and connected delivery; takes end-to-end ownership of outcomes across the portfolio of initiatives; drives quality and delivery commitments in the AI eraConnect Across Disciplines: Connects work across initiatives, architects, platforms, and business domains; inspires holistic solutions and reuse; translates specialized knowledge into accessible explanations; thinks like a business insiderCommunicate with Precision: Communicates with exceptional clarity and structure; frames trade-offs and priorities crisply; tailors the message from ELT sponsors to engineers; drives clarity and alignment as a core value across the portfolioThink in Systems: Shapes systems design and architecture practices across the initiatives; connects programs into a coherent whole; anticipates dependencies and risks; influences cross-team architecture decisions; creates clarity from complexityQUALIFICATIONSBasic QualificationsBachelor’s degree in Computer Science, Engineering, Information Systems, or a related field, with 12+ years of significant leadership experience in technology strategy, architecture, or large-scale program delivery.Demonstrated experience leading the technology strategy and delivery of multiple concurrent programs or initiatives, and connecting them into a coherent whole.Proven ability to lead and develop senior technical talent, including architects, principal engineers, and other senior specialists.Experience advising senior leaders on technology direction, priorities, trade-offs, and measurable business outcomes.Strong understanding of modern engineering practices, cloud platforms, data and integration patterns, AI-enabled delivery, security, reliability, and technology governance.Preferred QualificationsAdvanced degree in technology, engineering, business, or a related discipline preferred.Experience operating in a highly regulated, global enterprise environment with complex compliance, privacy, security, and risk expectations.Experience connecting multiple programs, platform portfolios, and AI-enabled initiatives into a coherent enterprise strategy.Track record of influencing C-suite or enterprise leadership teams, building trusted partnerships, and creating clarity in ambiguous, high-impact situations.Demonstrated strength in leading large, cross-functional teams with exceptional communication, organization, and stakeholder management.Leadership CapabilitiesConnected Strategy and Judgment: Connects the strategy of individual initiatives, the eight Digital Core Platforms, and enterprise architecture into one practical, connected direction that guides investment and execution.Leadership and Communication: Leads with clarity and confidence; communicates with exceptional precision and structure; organizes and coordinates complex work across many teams; frames trade-offs, builds alignment, and drives decisions.Technical Depth and Breadth: Brings enough hands-on technical and architectural credibility to guide senior architects, challenge assumptions, evaluate emerging technologies, and make sound enterprise-scale choices.Talent Leadership: Develops senior technical leaders and architects, builds succession plans, strengthens team capability, and creates an inclusive culture of accountability, curiosity, and continuous learning.AI and Modern Delivery Mindset: Understands how AI, automation, modern engineering, product thinking, and platform reuse can improve speed, quality, and value while maintaining appropriate controls and verification. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.Work Location Assignment: HybridAdditional Posting Locations: Tampa, FL, Collegeville, PA, Groton, CT, La Jolla, CA, Bothell, WA, Canada, Greece, Ireland, Switzerland and Walton Oaks (UK). On site strongly preferred. Remote locations will only be considered for internal candidates who are already designated remote.Last Date to Apply for Job: 9/28/2026The annual base salary for this position ranges from $230,900.00 to $384,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview. Relocation assistance may be available based on business needs and/or eligibility.Candidates must be authorized to be employed in the U.S. by any employer.U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.Sunshine ActPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email View email address on click.appcast.io. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.Information & Business TechSummaryLocation: United States - New York - New York City; Canada - Quebec - Remote; United States - Washington – Bothell; Canada - Ontario - Remote; United States - California - San Diego; United Kingdom - Walton Oaks; Greece - Thessaloniki Pylaia; United States - Connecticut - Groton; United Kingdom - Remote; Canada - Quebec - Quebec City; Greece-Thessaloniki Chortiatis; United States - Pennsylvania - Collegeville; Switzerland - Zug; Ireland - Dublin - Grange Castle; Ireland - Dublin - RingsendType: Full time