Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Software Engineer, Research Biology

$142.5k - $264.7k

Genentech

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The Computational Sciences Center of Excellence (CS CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and life-changing medicines for patients worldwide.

Within the CS CoE organisation, the Data and Digital Catalyst (DDC) organization leads the modernization of our computational and data ecosystems by integrating digital technologies across Research and Early Development to empower stakeholders, advance data-driven science and accelerate decision-making.

The Solutions team within the DDC Organization develops modernized and interconnected computational and data ecosystems. The Data Ecosystem is foundational to building solutions that accelerate the work done by our Computational and Bench Scientists and enable ML/AI tool creation and adoption. Our team specializes in building Data Pipelines and Applications for data acquisition, collection, storage, transformation, linkage and sharing.

We’re looking for a full-stack software engineer to join our team building modern software solutions for Pathology organizations across Roche.

The Opportunity:

  • You will develop and maintain systems for collecting, structuring, and storing diverse scientific and operational data that support advanced analytics, machine learning, and other data-driven initiatives.

  • You will deliver data flows and pipelines to support research pathology.

  • You will design and implement integrations between LIMS, ELN, workflow orchestration systems, AWS components, and other internal systems for scientific and operational data management.

  • You will implement novel AI-based solutions (ex. agents) to improve scientific and operational data management.

  • You will be an engineer on a team responsible for working under a technical lead and alongside a team of analysts with deep scientific expertise.

Who You Are:

  • You have a Bachelor’s or Master’s degree in Computer Science or similar technical field, or equivalent experience and 5+ years of professional experience in a full-stack software development role.

  • You have experience building enterprise-grade systems for R&D scientific data management.

  • You are proficient in programming languages such as Java, Kotlin, and/or Python.

  • You have experience building solutions with NoSQL databases, data warehouses, graph databases, and/or data lakes to store scientific data.

  • You have experience with event-driven architecture patterns and working with streaming platforms such as Apache Kafka.

  • You have experience with front-end frameworks (React, Vue), comfortable with developing APIs and MCPs and experience with Kubernetes for container orchestration.

  • You are proficient with Git, CI/CD tools such as GitHub Actions and Argo, and AWS.

  • You have excellent communication and presentation skills and have experience building solutions on cross-functional teams that include analysts, engineers, product managers, and technical leads.

Preferred Qualifications:

  • Experience deploying systems that include agentic components and low-level orchestration frameworks for agentic workflows such as LangGraph.

  • Experience in a life science or drug development environment is strongly preferred.

  • Knowledge of pathology processes and data is beneficial.

Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $142,500 - $264,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits (

#LI-JD1

#ComputationCoE

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants ( .

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Senior Software Engineer, Research Biology in South San Francisco, CA vacancy
  • $209k - $233k

     ...) is an Alphabet-founded research and development company whose...  ...our understanding of the biology that controls human aging...  ...: Calico seeks a Senior Machine Learning Research Engineer to join the team building...  ...~5+ years of relevant ML software engineering experience in... 
    Senior
    Flexible hours
    Shift work

    Calico LLC

    South San Francisco, CA
    15 hours ago
  • $209k - $233k

     ...Sciences LLC) is an Alphabet-founded research and development company whose...  ...increase our understanding of the biology that controls human aging. Calico will...  ...Position Description: Calico seeks a Senior Machine Learning Software Engineer (MLOps) to own the scaling,... 
    Senior
    Work experience placement

    Calico LLC

    South San Francisco, CA
    15 hours ago
  • $196k - $242k

     ...‑molecule drug discovery, structural biology, and bioinformatics with robust capabilities...  ...We are seeking an accomplished Senior Principal Research Scientist in Computational Chemistry...  ...Experience with Schrödinger modeling software and others (e.g., MOE, OpenEye) Programming... 
    Senior
    Temporary work
    Work at office
    Local area
    Work from home

    Initial Therapeutics, Inc.

    South San Francisco, CA
    3 days ago
  • A healthcare technology company based in San Francisco is seeking a Senior Full-Stack Engineer to build and optimize core research infrastructure. This role involves designing agentic systems and shipping features rapidly. Candidates should have senior-level experience... 
    Senior

    Sully

    San Francisco, CA
    4 days ago
  •  ...reduce the dollar and time cost of using biology to manufacture ~everything. Our...  ...is comprised of creative and talented engineers, data scientists, biologists, and more,...  ...Notion The role Mission As a Senior Software Engineer, you will ensure that your team... 
    Senior
    Remote work

    InVert™

    San Francisco, CA
    4 days ago
  •  ...deployed in real-world care.What You'll DoBuild and optimize core research infrastructure: evaluation pipelines, agent workflows,...  ...internal products that accelerate iteration across Research, QA, and Engineering.Hard RequirementsSenior-level full-stack engineering... 
    Senior
    Contract work

    Sully

    San Francisco, CA
    4 days ago
  • An established industry player is seeking a Senior Associate Scientist to join a dynamic team focused on advancing therapeutic concepts through innovative cell biology research. The ideal candidate will have a strong background in molecular and cellular biology, with expertise... 
    Senior

    TechDigital Group

    Brisbane, CA
    15 hours ago
  • $185k - $221.4k

     ...Senior Software Engineer San Francisco, CA Foresite Labs is a translational R&D team that derives...  ...measurement and population-scale biology and genetics to address unmet clinical...  ...hypotheses. We engage in translational research, transforming basic insights into therapeutic... 
    Senior
    Remote work
    Flexible hours

    Foresite Labs

    San Francisco, CA
    4 days ago
  • $75k - $100k

    NewLimit in South San Francisco is seeking a Senior/Research Associate with a Bachelor's degree in cell biology or molecular biology. Responsibilities include collaborating on large-scale single cell experiments, building recombinant DNA vectors, and applying viral vectors... 
    Senior

    NewLimit

    South San Francisco, CA
    4 days ago
  •  ...Francisco to support immune engager and CAR-T cell therapy programs within the Department of Research Oncology. You will design and execute experiments focused on T cell biology, contributing to innovative therapeutic approaches. The ideal candidate will possess a... 
    Senior
    Relocation package

    Genentech

    South San Francisco, CA
    2 days ago
  • Amgen is looking for a Senior Scientist in Research Computational Biology to enhance their therapeutic pipelines. The role involves applying data science expertise and deep biological insights to identify transformative therapeutic targets. The ideal candidate will have... 
    Senior

    Initial Therapeutics, Inc.

    South San Francisco, CA
    3 days ago
  • Onsite Job Title: Senior Associate Scientist Top Skills: 4-7 Experience in Cell/Tissue Culture...  ...the Protein Homeostasis-Oncogenesis cell biology group to design and perform experiments,...  ...Be organized and maintain documentation of all research. #J-18808-Ljbffr TechDigital Group
    Senior
    Work experience placement

    TechDigital Group

    Brisbane, CA
    15 hours ago
  •  ...ML Research Engineer, Foundation Models About the Team Join a world...  ...deep learning researchers, software engineers, and drug discovery...  ...research, structural biology, and computational chemistry...  ...available at various levels of seniority: Senior, Staff, and Principal... 
    Senior
    Temporary work

    Genesis Molecular AI

    San Mateo, CA
    1 day ago
  • $117.9k - $152.57k

     ...Gilead Sciences Research Informatics Coder/Programmer Gilead Sciences Research Informatics is expanding, and we are looking for...  ...analytics. In this role, you'll work at the intersection of software engineering and scientific innovation, creating tools that directly... 
    Senior
    For contractors
    Local area

    GILEAD

    San Mateo, CA
    1 day ago
  • $170k - $233k

     ...Sciences LLC) is an Alphabet-founded research and development company whose mission...  ...to increase our understanding of the biology that controls human aging. Calico will...  ...TensorFlow, PyTorch, and/or JAX Strong software engineering skills and substantial expertise in... 
    Senior

    Calico LLC

    South San Francisco, CA
    15 hours ago
  • $170k - $233k

     ...LLC) is an Alphabet-founded research and development company whose...  ...increase our understanding of the biology that controls human aging....  ...publications, open-source software, and public-facing tools Position...  ...level) or 5+ years (for Senior Scientist level) of additional... 
    Senior

    Calico LLC

    South San Francisco, CA
    15 hours ago
  • $75k - $100k

     ...machine learning models to unravel the biology of epigenetic aging and disease using experiments...  ...scale. Position We are seeking a Senior/Research Associate with experience in molecular...  ...are at the heart of our discovery engine, allowing us to rapidly search for epigenetic... 
    Senior
    Work experience placement

    NewLimit

    South San Francisco, CA
    4 days ago
  • $95k - $115k

    We are seeking a highly motivated and skilled Senior/Research Associate to join our Analytical Developability team. The successful candidate...  ...: Work closely with Production, Conjugation, Development, Biology and leadership teams to advance molecules from screening to development... 
    Senior

    Valid8 Financial, Inc.

    South San Francisco, CA
    2 days ago
  • $90k - $105k

     ...pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale. Position NewLimit is seeking a Senior Research Associate with experience in liver biology or in vivo physiology to... 
    Senior
    Work experience placement

    NewLimit

    South San Francisco, CA
    4 days ago
  • $55 - $60 per hour

     ...Job Description Addition Therapeutics is seeking a researcher with experience in T cell engineering and gene editing, either in industry or an academic setting...  ...engineering, gene editing, immunology, synthetic biology, molecular biology, and cell biology. Collaborating... 
    Senior
    Hourly pay
    Contract work
    Flexible hours

    Addition Therapeutics

    South San Francisco, CA
    1 day ago
  •  ...ML Research Scientist, Foundation Models About the Team Join...  ...deep learning researchers, software engineers, and drug discovery pioneers...  ...just apply machine learning to biology; we are conducting...  ...available at various levels of seniority: Senior, Staff, and Principal... 
    Senior
    Temporary work

    Genesis Molecular AI

    San Mateo, CA
    3 days ago
  • $257.4k - $330k

     ...Senior / Principal Machine Learning Scientist San...  ...-modal, multiscale biology from virtual cells to...  ...team of scientists and engineers focused on transforming...  ...technical vision and research strategy for a core domain...  ...Experience with software development methodologies... 
    Senior
    Contract work
    Work experience placement
    Local area

    Altos Labs

    San Francisco, CA
    1 day ago
  • $90k - $110k

    About NewLimit NewLimit is seeking a Senior Research Associate with strong experience in molecular biology and translational biomarker assay development to join our team. This role will contribute to the development and execution of pharmacokinetic (PK) and pharmacodynamic... 
    Senior

    NewLimit

    South San Francisco, CA
    15 hours ago
  • $122k - $130k

    Senior Research Associate, Discovery Biology Join to apply for the Senior Research Associate, Discovery Biology role at BBOT Senior Research Associate,...  ...therapies. Develop novel tools (such as genetically engineered cell lines) and assays as needed to support the group... 
    Senior
    Full time
    Temporary work

    BBOT

    South San Francisco, CA
    3 days ago
  • $168.1k - $312.3k

     ...drug discovery and development. Roche's Research and Early Development organisations at Genentech...  ...a flat scientific structure in which senior scientists define their own research...  ...and advances the scientific ecosystem. In biology, many exciting research questions cannot... 
    Senior
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    5 days ago
  • $270k - $294.5k

     ...Senior Director, Clinical Research (Medical Director) Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases... 
    Senior
    Summer holiday
    3 days per week

    Eikon Therapeutics

    Millbrae, CA
    1 day ago
  • $120k - $160k

     ...Tenvie Therapeutics is developing precision-engineered small molecule therapies to address core...  ...colleagues in chemistry, pharmacology, biology, DMPK, and project teams. The ideal...  ...technologies, and approaches to ongoing research Contribute to a strong team culture grounded... 
    Senior
    Local area

    Tenvie Therapeutics

    Brisbane, CA
    2 days ago
  • $156k - $191k

     ...LLC) is an Alphabet-founded research and development company whose...  ...deepen our understanding of the biology that controls human aging....  ...motivated and creative Scientist/Senior Scientist, Aging Biology to...  ...with Prism or similar software Exceptional organizational skills... 
    Senior
    Flexible hours
    Shift work

    Calico Life Sciences

    South San Francisco, CA
    2 days ago
  • $147k - $191k

     ...through our deep commitment to degeneration biology and principles of translational medicine...  ...‑derived models, ex vivo systems, and engineered cell lines enhancing precision of...  ...Actively participate in interdisciplinary research collaborations with Denali scientists and... 
    Senior
    Contract work
    Local area

    Denali Therapeutics

    South San Francisco, CA
    3 days ago
  • $268k - $384k

     ...Senior / Principal ML Scientist, Foundation Models for Life Sciences...  ..., the Foundation Models team researches and develops large-scale...  ...life science data, spanning biological sequences, molecular structures...  ...Lila's closed-loop discovery engine. This is a high-impact IC... 
    Senior
    Full time
    Work at office
    Local area
    Flexible hours

    Lila Sciences

    San Francisco, CA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Software Engineer, Research Biology. Be the first to apply!