Regional Business Director - MI Clarity (Northeast)

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Regional Business Director – MI Clarity is a field-based commercial leadership role responsible for driving regional and national market adoption, utilization growth, and strategic expansion of MI Clarity, an AI-powered prognostic assay designed to assess both early and late distant recurrence risk in postmenopausal patients with HR-positive/HER2-negative, node-negative early-stage breast cancer.

This leader will play a critical role in building and scaling a high-performing commercial organization focused on healthcare providers involved in the diagnosis and treatment of early-stage breast cancer, including medical oncologists, breast surgeons, pathologists, breast centers, and integrated health systems. The Regional Business Director will lead and develop a team of Account Executives responsible for driving awareness, clinical adoption, and utilization of MI Clarity across targeted geographies and strategic accounts.

The Regional Business Director will develop and execute commercial strategies that create demand, accelerate adoption, expand market penetration, and position Caris as a differentiated leader in AI-driven prognostic oncology solutions. The ideal candidate will possess a strong builder mentality and demonstrated success leading commercial teams within oncology, molecular diagnostics, pathology, healthcare technology, or related healthcare markets. This individual must thrive in a fast-paced launch environment and demonstrate strong capabilities in sales leadership, market development, clinical strategy, and cross-functional collaboration.

Job Responsibilities

• Develop and execute regional and national commercial strategies to drive MI Clarity adoption, utilization, and market penetration.

• Build, lead, coach, and develop a high-performing team of Account Executives.

• Establish a culture of accountability, urgency, customer focus, and execution excellence.

• Drive new account acquisition and account expansion within oncology, pathology, breast surgery, and integrated delivery networks.

• Identify, prioritize, and pursue high-value market opportunities and strategic accounts.

• Develop go-to-market strategies that accelerate adoption within community oncology practices, academic medical centers, and health systems.

• Build and maintain executive-level relationships within key accounts and healthcare systems.

• Engage oncology leadership, pathology leadership, breast program directors, and C-suite stakeholders.

• Collaborate with pathologists and operational stakeholders to optimize tissue access and workflow integration.

• Lead strategic discussions related to value-based care, clinical utility, and personalized treatment planning.

• Maintain advanced knowledge of breast cancer treatment pathways, prognostic and predictive testing, molecular diagnostics, digital pathology, AI-driven technologies, and oncology reimbursement dynamics.

• Coach teams on effective clinical selling and evidence-based customer engagement.

• Ensure field teams effectively communicate clinical data, validation studies, and differentiation from competing assays.

• Recruit, onboard, train, and mentor top commercial talent.

• Conduct regular field coaching, business reviews, pipeline management, forecasting, and performance development activities.

• Establish clear territory expectations, KPIs, and performance goals.

• Foster collaboration and alignment across field teams and internal stakeholders.

• Support product launch initiatives, messaging refinement, and field readiness programs.

• Provide marketplace feedback and competitive intelligence to Commercial Leadership and Marketing teams.

• Provide field insights that inform marketing strategy, customer engagement models, and future product development.

• Ensure accurate forecasting, CRM utilization, reporting, and territory analytics.

• Maintain compliance with all company policies, industry regulations, and healthcare compliance standards.

• Support meetings, conferences, advisory boards, and trade shows as required.

• Partner cross-functionally with Medical Affairs, Marketing, Operations, Pathology, Market Access, and Executive Leadership teams to support commercial success.

• Maintain assigned company assets.

• Perform other related duties as assigned.

Required Qualifications

• Bachelor’s degree required.

• Minimum 5 years of people leadership experience leading successful commercial teams.

• Proven success building, leading, and developing high-performing sales organizations.

• Demonstrated success in market development, new business acquisition, customer adoption, and revenue growth.

• Experience leading teams through product launches, commercialization initiatives, or high-growth business environments.

• Strong coaching, communication, leadership, and strategic planning skills.

• Experience utilizing CRM platforms, sales analytics, forecasting, and business intelligence tools.

• Ability to travel regularly within assigned geography.

Preferred Qualifications

• Experience in oncology, diagnostics, molecular testing, pathology, precision medicine, medical device, biotechnology, pharmaceutical, healthcare technology, or related healthcare industries.

• Experience leading first-line managers or multi-level commercial organizations.

• Experience launching innovative healthcare products, services, or technologies.

• Familiarity with oncology care delivery, pathology workflows, precision medicine, or integrated healthcare systems.

• Experience working with large health systems, IDNs, academic medical centers, or enterprise accounts.

• MBA or advanced business, healthcare, or scientific degree.

• Experience commercializing AI-enabled technologies, digital health platforms, or advanced diagnostic solutions.

Physical Demands

• Ability to sit or stand for extended periods.

• Ability to travel frequently by car and air.

• Ability to lift routine office and meeting materials.

Additional Information

• Travel required, including evenings, weekends, and holidays as needed.

• This position requires substantial field engagement with customers and commercial teams.

• Valid driver’s license, clean driving record, reliable vehicle, and automobile insurance meeting company requirements are required.

Annual Hiring Range

$170,000 - $200,000

Actual compensation offer to candidate may vary from posted hiring range based upon geographic location, work experience, education, and/or skill level. The pay ratio between base pay and target incentive (if applicable) will be finalized at offer.

Conditions of Employment: Individual must successfully complete pre-employment process.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.