Oligonucleotide Chemist - Targeted Delivery & Conjugates
$106k - $138kDenali Therapeutics Inc.
Denali Therapeutics Inc. in South San Francisco is seeking a candidate with expertise in oligonucleotide synthesis and bioconjugation to contribute to innovative drug development. The role entails designing and synthesizing oligonucleotide therapeutics, supporting discovery programs, and collaborating with various scientific teams. Applicants should have a minimum of 2 years of experience in related fields, with strong technical skills, effective communication abilities, and a commitment to collaborative research. The position offers a competitive salary range of $106,000 to $138,000, depending on qualifications and experience. #J-18808-Ljbffr Denali Therapeutics Inc.
$106k - $138k
...meaningful therapeutics to patients. This role will apply oligonucleotide chemistry and bioconjugation expertise to advance... .... Design and generate antibody-oligonucleotide conjugates to support targeted delivery of siRNA/ASOs using established and emerging bioconjugation...SuggestedLocal area$175k - $200k
BioSpace in South San Francisco is seeking a Senior Protein & Peptide/Chemical-Protein Conjugate Formulation Scientist to lead the development and optimization of formulations for novel therapies. This role requires a PhD and 5-10+ years of experience in protein and peptide...Suggested- ...Francisco is seeking a Senior Scientist I in Medicinal Chemistry. This role involves designing and driving strategies for integrin-targeted therapeutics, translating complex data into actionable insights, and collaborating with multidisciplinary teams. The ideal...Suggested
- ...biology to improve internal structure-cell interactions for targeted delivery and immune response modulation. Description The Senior Scientist... .... Preferred Qualifications Experience with antibody‑drug conjugates (ADCs), linker‑payload systems, or similar targeted delivery...Suggested
$196k - $242k
...develop tailored, potentially first‑in‑class targeted therapies aligned to the genetic drivers... ...synthetic lethality and antibody‑drug conjugates (ADCs) for molecularly defined solid... ...for a highly experienced computational chemist with a strong track record of advancing...SuggestedTemporary workWork at officeLocal areaWork from home$196k - $242k
...develop tailored, potentially first‑in‑class targeted therapies aligned to the genetic drivers... ...synthetic lethality and antibody‑drug conjugates, or ADCs, for molecularly defined solid... ...drug design meetings with medicinal chemists and provide senior‑level, hands‑on drug...Temporary workLocal areaRemote work1 day per week- ...records in drug development timelines. You'll manage peptide synthesis and testing, contributing directly to our first-in-human dosing targets in 2026. The ideal candidate will have strong technical skills and a knack for innovation in a fast-paced startup environment. This...
- ...pioneering drug discovery for intrinsically disordered proteins—targets that have eluded conventional approaches in neurodegeneration,... ...oncology, and cardiometabolic disease. We’re seeking a Computational Chemist to help generate novel molecules for a variety of targets and...
$124.3k - $230.9k
...development. The Scientist will play a key role in advancing a diverse pipeline including synthetic small molecules, peptides, oligonucleotides, and drug delivery systems (e.g., lipid nanoparticles, polymer nanoparticles), working in a highly collaborative, cross-functional...Local areaRelocation package$124.3k - $230.9k
...the following areas for analysis of small molecules, peptides, oligonucleotides, polymers, or nanoparticles: mass spectrometry method... ...chemistry and formulation processes of nanoparticle‑based drug delivery systems, exposure to CMC, regulatory submissions, or analytical...Local areaRelocation package$155.48k - $189.02k
...application portal. Department: Citywide Job class: 2488-Supervising Chemist Salary range: $155,480.00 - $189,020.00 Role type: Permanent... ...and evaluates the work of chemists and technicians in the delivery of water quality for an assigned section; prepares performance...Permanent employmentFull timeSecond jobWork at officeLocal areaMonday to FridayWeekend work$26 per hour
...Job Description Job Description Apply today and start next week as a Delivery Driver! NO EXPERIENCE REQUIRED! EARN UP TO $30.00 HOURLY WITH BONUSES! WILLING TO TRAIN THE RIGHT CANDIDATES! Based in South SF. No Commercial Driver's License needed to be a delivery...Hourly payFull timeImmediate startShift workWeekend work$28 - $32 per hour
...Astrix Scientific Recruiter | Connecting Top Talent in Life Sciences Our client, a cutting-edge biotech company, is seeking an Organic Chemist to join their dynamic team. If you're passionate about advancing precision medicine and thrive in a fast-paced, innovative...Full timeContract work- ...We currently have a role available for a Pharma Bioanalytical Chemist at our South San Francisco site. Job duties include, but are not... ...environment with flexibility and an adaptable approach to goal delivery. This is a day shift position (approx. 8a-5p local time)....Contract workLocal areaRelocation packageDay shift
$196k - $242k
IDEAYA Biosciences in South San Francisco is seeking a Senior Principal Research Scientist in Computational Chemistry. This senior individual-contributor role demands significant pharmaceutical industry experience, focusing on advancing drug discovery programs. Responsibilities...$124.3k - $230.9k
...record. Deep hands‑on expertise in one or more of the following areas for the analysis of synthetic small molecules, peptides, oligonucleotides, polymers, or nanoparticles: mass spectrometry method development (HRMS, MS/MS, structural elucidation); chromatographic...Local areaRelocation package$196k - $242k
IDEAYA Biosciences, Inc. is looking for a Senior Principal Research Scientist in Computational Chemistry in South San Francisco, CA. This role involves leading drug design efforts and mentoring while applying computational methods to influence project outcomes. Working ...Remote job1 day per week$175k - $200k
...2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) ORIC-114, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two...- A leading biotechnology firm is seeking a Scientific Researcher (LNP Formulation Screening) based in South San Francisco, CA. The ideal candidate will have a BS/MS in Chemistry or related field and 1-5 years of relevant experience. You will be responsible for high-throughput...
$160k - $180k
Septerna is seeking a Staff Scientist, Pharmaceutical Development, based in South San Francisco, CA. This role focuses on formulation development to support the company's small molecule pipeline. The ideal candidate will have a degree in Pharmaceutics and extensive industry...- ...significant responsibilities including managing compound purifications, ensuring analytical methods are sound, and supervising junior chemists. The successful candidate will hold a Ph.D. and have a minimum of 5 years of experience in drug discovery, particularly in small...
- ...screening technologies used in industrial‑scale drug discovery for the entire class of GPCRs. Septerna has an emerging pipeline of GPCR‑targeted small molecule programs with potential for growth to target many GPCRs that have been undruggable and unexploited to date. We are...Interim role
$120k - $147k
A biopharmaceutical company in South San Francisco seeks a Senior Research Associate II in Medicinal Chemistry. The role involves applying expertise in organic chemistry to synthesize and characterize novel molecules. Ideal candidates have a B.S./M.S. in Chemistry and ...$6,891 per month
...Job Overview Lawrence Berkeley National Laboratory is hiring a Chemist Postdoctoral Scholar within the Energy Technologies and Systems division. You will direct and carry out diagnostic investigations of advanced energy storage systems; define the fundamental issues affecting...Full timeContract work- ...team of methods developers. Deploy workflows onHPC and cloud platforms and deliver user-friendly web-based interfaces tomedicinal chemists across gRED. Desired Qualifications BS, MS, or PhD degreein a life or physical science or a computational field. Expert in Python...Contract work
$40 - $80 per hour
...lower cost non‑linear fluorescence imaging that can drive progress in life sciences research. Job Overview We’re looking for a chemist on a part‑time contract (remote or hybrid in‑person) to help us identify promising molecules that improve our fluorescence...Hourly payFull timeContract workPart timeRemote work- ...San Francisco. This role involves supporting formulation and drug product development activities for large molecule biotherapeutics targeting neurodegenerative diseases. The ideal candidate should have a BS or MS in a relevant field, with over 2 years of experience in...
- Clinical Informatics Pharmacist Specialist Join the healthcare information technology team that's turning drug and medical device data into knowledge used by thousands of hospitals; the majority of U.S. health plans, retail pharmacies, and pharmacy benefit managers;...
$80k - $110k
...Location: Bay Area -- Albany, CA (Hybrid) A pioneering company in eco-friendly home care products is looking to add a Formulation Chemist to its expanding R&D team based in the Bay Area, CA. This is a full-time hybrid position, with relocation support. The...Full timeLocal areaRemote workRelocation package$127.2k - $190k
Merck & Co. is seeking a Scientist/Sr Scientist/Staff Scientist in South San Francisco to innovate on our silicon-based DNA synthesis platform. The ideal candidate will drive research projects focused on optimizing DNA synthesis cycles and collaborate with various biological...
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