Principal Fluid Systems Engineer - Pharmaceutical Payloads
$170k - $220kVarda Space Industries
About Varda Low Earth orbit is open for business . Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules.
From life-saving pharmaceuticals to more powerful fiber optics, there is a world of products used on Earth today that can only be manufactured in space. Varda is accelerating innovation in the orbital economy by creating both the products and infrastructure needed so space can directly benefit life on Earth. Our mission is to expand the economic bounds of humankind.
Our team is uniquely suited to accomplishing this goal, with leadership and staff comprised of veterans from SpaceX, Blue Origin, major pharmaceutical companies and Silicon Valley. Varda was founded in January 2021 by Will Bruey and Delian Asparouhov with significant backing from world class investors including Khosla Ventures, Lux Capital, Founders Fund, Caffeinated Capital, General Catalyst, and Also Capital.
Varda is headquartered in El Segundo, California, where we have offices and a production facility where our vehicles, equipment, and materials are built, integrated, and tested. Varda also has offices in Washington, DC and Huntsville, AL. Join Varda, and work to create a bustling in-space ecosystem. About this Role As a Principal Fluid Systems Engineer on Varda's Payload team, you will define and lead the development of first-of-its-kind electromechanical fluid handling hardware that manufactures pharmaceuticals in microgravity, endures hypersonic reentry, and returns to Earth for material extraction. Your payloads will precisely meter, mix, filter, transport, and thermally control pharmaceutical materials in compact spacecraft-compatible hardware. You'll shape the architecture and technical direction for pharmaceutical payloads-guiding project teams from requirements synthesis through development, on-orbit operation, recovery, and iteration for future missions. You'll collaborate closely with pharmaceutical scientists, process engineers, internal leadership, and spacecraft subsystem teams to translate mission objectives into qualified hardware that flies in months, not years. This role is ideal for engineers who combine deep mechanical and fluid systems expertise with the cross-functional breadth to define foundational in-space pharmaceutical manufacturing infrastructure.
Responsibilities
From life-saving pharmaceuticals to more powerful fiber optics, there is a world of products used on Earth today that can only be manufactured in space. Varda is accelerating innovation in the orbital economy by creating both the products and infrastructure needed so space can directly benefit life on Earth. Our mission is to expand the economic bounds of humankind.
Our team is uniquely suited to accomplishing this goal, with leadership and staff comprised of veterans from SpaceX, Blue Origin, major pharmaceutical companies and Silicon Valley. Varda was founded in January 2021 by Will Bruey and Delian Asparouhov with significant backing from world class investors including Khosla Ventures, Lux Capital, Founders Fund, Caffeinated Capital, General Catalyst, and Also Capital.
Varda is headquartered in El Segundo, California, where we have offices and a production facility where our vehicles, equipment, and materials are built, integrated, and tested. Varda also has offices in Washington, DC and Huntsville, AL. Join Varda, and work to create a bustling in-space ecosystem. About this Role As a Principal Fluid Systems Engineer on Varda's Payload team, you will define and lead the development of first-of-its-kind electromechanical fluid handling hardware that manufactures pharmaceuticals in microgravity, endures hypersonic reentry, and returns to Earth for material extraction. Your payloads will precisely meter, mix, filter, transport, and thermally control pharmaceutical materials in compact spacecraft-compatible hardware. You'll shape the architecture and technical direction for pharmaceutical payloads-guiding project teams from requirements synthesis through development, on-orbit operation, recovery, and iteration for future missions. You'll collaborate closely with pharmaceutical scientists, process engineers, internal leadership, and spacecraft subsystem teams to translate mission objectives into qualified hardware that flies in months, not years. This role is ideal for engineers who combine deep mechanical and fluid systems expertise with the cross-functional breadth to define foundational in-space pharmaceutical manufacturing infrastructure.
Responsibilities
- Define requirements, architecture, and development plans for pharmaceutical manufacturing payloads
- Establish fluid system design standards for component selection and qualification, sealing, contamination control, thermal control, and verification/validation
- Lead project teams to develop of precision fluid systems incorporating valves, pumps, pistons, manifolds, tubing, fittings, seals, filters, sensors, and thermal control systems
- Drive system-level analyses, trade studies, and risk reduction using a variety of tools (hand calcs, Python/MATLAB models, FEA, etc. as needed)
- Lead build and test campaigns for prototypes and flight hardware to characterize performance and reliability
- Synthesize cross-functional inputs from business development, pharmaceutical science, process engineering, and spacecraft subsystem teams to develop requirements for new pharmaceutical payloads
- Develop standards for subsystem requirements, ICDs, verification plans, test reports, and recovery procedures
- Represent Varda in technical discussions with internal leadership, external partners, customers, and government stakeholders
- Lead continuous improvement and incorporation of lessons learned
- Mentor senior and entry-level engineers and shape best practices
- BS/BEng in Mechanical, Aerospace, Mechatronics, Biomedical, Chemical, or related engineering discipline
- 7+ years of experience designing, integrating, testing, and troubleshooting electromechanical hardware
- Deep mechanical and fluid systems expertise with breadth in at least two adjacent disciplines such as avionics, software, thermal, optics, test, precision instrumentation, etc.
- Track record leading project teams through full-cycle electromechanical space flight hardware development
- Extensive experience with valves, pumps, pistons, tubing, manifolds, fittings, seals, filters, sensors, metering hardware, thermal-control hardware, and/or compact fluidic assemblies
- Excellent communication skills with customer, executive, and cross-disciplinary technical audiences
- 3+ years of cross-functional project leadership experience
- Prior full-cycle technical leadership of precision fluid-handling hardware for relevant applications
- In Space: ECLSS, low-thrust propulsion, astronaut suits, spacecraft thermal control, etc.
- On Earth: semiconductor process equipment, biotech process equipment, analytical instruments, medical devices, etc.
- Extensive experience planning and executing aerospace environmental testing (vibration, TVAC, EMI/EMC)
- Familiarity with microgravity fluid behavior, capillary-driven flows, gas/liquid separation, two-phase flow, cGMP principles, cleanroom practices, or regulated hardware environments
- Salary range: $170,000 - $220,000/per year
- This role is on-sitein El Segundo, CA
- Leveling and base salary is determined by job-related skills, education level, experience level, and job performance
- You will be eligible for incentives in the form of stock options and/or long-term cash awards
- Varda, like all employers, must ensure that its employees working in the United States are lawfully authorized to work in the U.S. Additionally, our employees are exposed to and have access to certain export-controlled items. At present, some of our technology to which employees have access requires a license to be exported to individuals other than "U.S. Persons" as defined in U.S. export regulations. Because our employees are provided access to export-controlled items, our current policy is to only hire "U.S. persons" who are permitted to have access to our technology without an export license.
"US person" means: U.S. citizen, U.S. lawful permanent resident, or protected individual as defined by 8 U.S.C. 1324b(a)(3) (i.e., individual admitted to the U.S. as a refugee or granted asylum in the U.S.)
Learn more about the ITAR here.
- Exciting team of professionals at the top of their field working by your side
- Equity in a fully funded space startup with potential for significant growth (interns excluded)
- 401(k) matching (interns excluded)
- Unlimited PTO (interns excluded)
- Health insurance, including Vision and Dental
- Lunch and snacks provided on site every day. Dinners provided twice a week.
- Maternity / Paternity leave (interns excluded)
Vacancy posted 5 days ago
Similar jobs that could be interesting for youBased on the Principal Fluid Systems Engineer - Pharmaceutical Payloads in El Segundo, CA vacancy
$110.3k - $165.5k
...have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and... .... Northrop Grumman Space Systems is seeking a Principal Mission Payload Systems Engineer to join our team in Redondo Beach, California. This...PrincipalFull timeFor subcontractorRemote workRelocation packageMonday to ThursdayFlexible hoursShift work- ...Senior Systems Engineer Critical Energy is an innovative, early-stage, venture-backed cleantech company on a mission to accelerate the... ...versatile Senior Systems Engineer with experience in thermal and fluid dynamics to support the design, development, testing, and...SuggestedImmediate startFlexible hours
$114k - $171k
...opportunities to work on revolutionary systems that impact people's lives around... ...Space Sector has an opening for a Principal Thermal Systems Engineer/Sr. Principal Thermal Systems Engineer... ...for spacecraft subsystems, payloads and directed energy systems Demonstrated...PrincipalFull timeRelocationMonday to ThursdayFlexible hoursShift work$148.5k - $199k
...pioneers of out-of-the-box communication systems for satellites, UAVs, launch vehicles... ...team. We are looking to add a Principal Systems Engineer I to our team. If you enjoy working... ...architecture concepts, sub-system design, payload design, requirements development,...PrincipalPermanent employmentFull timeContract workWork experience placementLocal area$148.5k - $199k
...pioneers of out-of-the-box communication systems for satellites, UAVs, launch vehicles,... ...years. They are BIG and super capable RF payload rideshare SmallSats. Our launches are already... ...As a Spacecraft Communication Systems Engineer , you will own the design,...PrincipalPermanent employmentFull timeContract workWork experience placementLocal area$192.5k - $221.38k
...infrastructure, from in-orbit pharmaceutical processing to reliable... ...computational fluid dynamics (CFD) simulations... ...: BS in an engineering of physics & 5+ years... ...Pay Range Principal Aerodynamics Engineer:... ...eligibility verification system operated by the U.S. Citizenship...PrincipalPharmaceuticalPermanent employment$100.3k - $150.4k
...Fluid Systems Engineer (Senior Member of Technical Staff - Aeronautical and Mechanical Engineering) The Aerospace Corporation is the trusted partner to the nation's space programs, solving the hardest problems and providing unmatched technical expertise. As the operator...For contractorsImmediate startRemote workRelocation packageFlexible hours- ...Job Description Job #217557 Chipton-Ross is seeking a Payload System Engineer (Level 6) for a contract opportunity in El Segundo, CA. 100% onsite BASIC QUALIFICATIONS (REQUIRED SKILLS/EXPERIENCE) Accredited Bachelor of Science degree from an accredited...Full timeContract workLocal areaDay shift
- ...SIGINT Payload System Engineer Location: El Segundo, California (On-site) Employment Type: Contract Role Overview We are seeking a System Architect with demonstrated expertise in Signals Intelligence (SIGINT). This role is centered on creating and describing...Contract work
$200k - $250k
...Director, Mechanisms Engineering - Pharmaceutical Payloads El Segundo, California, United States About Varda Low Earth orbit is open... ...development and flight of precision electromechanical fluid-handling systems that process and crystallize pharmaceutical...PharmaceuticalPermanent employment$171.4k - $257.1k
...innovative solutions that span satellite, launch, ground, and cyber systems for defense, civil and commercial customers. When you join... ...systems. The ESS Program seeks a Sr. Space Systems Lead Payload Engineer to serve as the technical leader for payload engineering...Full timeContract workFor contractorsWork at officeImmediate startRemote workWorldwideRelocation packageFlexible hours$142.2k - $213.4k
...opportunities to work on revolutionary systems that impact people's lives around... ...Aeronautics Systems seeks a Sr. Principal Mission Systems Electronics Engineer for the Autonomous Collaborative... ...capabilities (including air vehicles, payloads, ground segments, mission planning...PrincipalFull timeInternshipRemote workWorldwideRelocation packageShift work$133k - $175k
...space infrastructure, from in-orbit pharmaceutical processing to reliable and economical... ...space ecosystem. Senior Propulsion Engineer Ground Fluids El Segundo, California, United... ...authority for our ground fluid systems - the backbone of every mission we fly...PharmaceuticalPermanent employmentFull time$114k - $171k
...employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for... ...'s Aeronautics Systems sector is seeking a Cyber Systems Engineer (Principal or Senior Principal Level) to join our team of qualified,...PrincipalRelocation packageShift work$108.2k - $162.4k
...opportunities to work on revolutionary systems that impact people's lives around the world... ...solutions for global security. Our Engineering and Sciences (E&S) organization pushes the... ...Defense Cyber Team has an opening for a Principal or Sr. Principal Cybersecurity Systems Engineer...PrincipalRelocation packageShift work- ...Systems Integrated Product Team Lead Collins Aerospace is a leader in technologically advanced, intelligent solutions that help... ...contribute to a team responsible for systems and cyber security engineering tasks related to our next-generation security-enabled mission...PrincipalRelocationRelocation package
- ...Senior Systems Engineer - M365 El Segundo, California, United States About Varda Low Earth orbit is open for business. Varda... ...development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules....PharmaceuticalPermanent employmentFull time
$115k - $145k
...infrastructure, from in-orbit pharmaceutical processing to reliable and... ...ecosystem. Thermal Hardware Engineer Role and expectations: The... ...of vehicle thermal and fluid systems. This role encompasses the development... ...spacecraft disciplines (payload, structures, avionics,...PharmaceuticalPermanent employment- ...Principal Systems Engineer The Multi-Domain Assured Navigation & Timing Applications (MANTA) group within the Mission Critical Products organization is hiring a Principal Systems Engineer to join our Mission Systems organization in support of the Global Positioning...PrincipalRelocation
- ...Systems Engineer Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced... ...and gas exploration and production, medical imaging and pharmaceutical research. We are looking for individuals who thrive on making...PharmaceuticalPermanent employmentWork experience placementLocal areaFlexible hours
$133k - $170k
...development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules.... ...ecosystem. About This Role Varda is seeking a Senior Systems Engineer to serve as the primary architect for mission safety and...PharmaceuticalPermanent employment$79.3k - $131.4k
...employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for... ...Northrop Grumman Defense Systems is hiring a Systems Engineer (level 2)/Principal Systems Engineer (level 3) to join its team in Roy, UT,...PrincipalFull timeRelocation packageMonday to ThursdayShift work$87.6k - $131.4k
...Northrop Grumman Systems Engineer/Principal Systems Engineer At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for generations to come. Our pioneering and inventive...PrincipalFull timeRelocation packageMonday to ThursdayShift work$114k - $171k
...Principal Or Senior Principal Level Requirements And Verification Systems Engineer At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for generations to come. Our...PrincipalFull timeRemote workShift work$79.3k - $118.9k
...employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for... ...Grumman Defense Systems is seeking a Systems Systems Engineer / Principal Systems Engineer supporting activities including flight simulator...PrincipalFull timeRelocation packageShift work$170k - $215k
...infrastructure, from in-orbit pharmaceutical processing to reliable and... ...highly motivated and creative Principal Scientist, Analytical... ...Act as a program responsible engineer who will direct and lead all... ...employment eligibility verification system operated by the U.S....PrincipalPharmaceuticalPermanent employment$79.3k - $91.8k
...employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for... ...Defense Systems sector (NGDS) is seeking a Systems Engineer or Principal Systems Engineer to join our growing team of diverse professionals...PrincipalRelocation packageShift work- ...Systems Engineering Professional Collins Aerospace is a leader in technologically advanced, intelligent solutions that help redefine the aerospace and defense industry. With a comprehensive portfolio and deep technical expertise, we help customers meet the demands of...PrincipalRelocationRelocation package
$200k - $230k
...infrastructure, from in-orbit pharmaceutical processing to reliable... ...About this Role As a Principal Guidance, Navigation, and Controls Engineer, you will own the full... .... You will perform system analyses, including simulations... ..., gas dynamics, fluids, and thermodynamics...PrincipalPharmaceuticalPermanent employmentFull timeFlexible hours$114k - $171k
...Principal Or Senior Principal Systems Modeling & Simulation Engineer At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for generations to come. Our pioneering and...PrincipalFull timeRemote workShift work
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Fluid Systems Engineer - Pharmaceutical Payloads. Be the first to apply!
Related searches
- senior civil engineer project manager El Segundo, CA
- director systems engineering El Segundo, CA
- engineering director El Segundo, CA
- chief engineer El Segundo, CA
- data center chief engineer El Segundo, CA
- principal developer El Segundo, CA
- hotel chief engineer El Segundo, CA
- director software engineering El Segundo, CA
- principal engineer El Segundo, CA
- general engineer El Segundo, CA

