Senior Principal Product Manager
$227.05k - $316kF. Hoffmann-La Roche AG
Senior Principal Product Manager
Genentech, Inc. seeks a Senior Principal Product Manager at its South San Francisco, CA location.
Duties: Refine the strategy and product vision for a product family in the Therapeutics Discovery Domain to enable the highest priority scientific outcomes. This includes developing the product roadmap, stakeholder management, conducting market research, and devising a go-to-market strategy. Product family owner that drives execution of their area to ensure maximum impact. This includes eliciting requirements, backlog prioritization, and budget. Advocate for future-facing solutions, anticipating emerging capabilities and integrating these in their roadmaps. Identify key trends, technologies, methodologies and take an Open Source first, Cloud first, API first and AI first approach. Contribute to consolidation and deprecation of legacy systems and overall reduction of accumulated technical debt. Establish and cultivate strong internal and external partnerships and relationships with extended collaborators in DDC, CS CoE and beyond.
Education and experience required: Ph.D. degree or foreign equivalent in Biology, Biotechnology, Biochemistry or a closely related field and 4 years of experience as an Informatics Systems Analyst, Scientific Business Analyst, IT Professional, Scientific Researcher or a closely related role.
Alternative education and experience required: Master's degree or foreign equivalent in Biology, Biotechnology, Biochemistry or a closely related field and 7 years of experience as an Informatics Systems Analyst, Scientific Business Analyst, IT Professional, Scientific Researcher or a closely related role.
Must have minimum of 2 years of experience with the following:
- Agile and Scrum Methods
- Software tools such as JIRA, Confluence, LucidChart, Miro, Trello
- Biotechnology/Biologics based drug discovery process at early stage
- Writing basic queries to relational databases (SQL-based)
- Structure Data interchange formats (JSON)
- All phases of the software development process including requirements gathering, design, implementation, testing, release, and maintenance
- Documenting detailed software requirements, user stories, business processes, and/or software specifications for both custom and Commercial-Off-The-Shelf (COTS) systems
Telecommuting permitted up to 2 days per week
Worksite: 1 DNA Way, South San Francisco CA, 94080
The expected annual salary range for this position based on the primary location for this position of South San Francisco, California is $227,049 to $316,000 per year. Actual pay within the range will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
- Warner Media, LLC. is seeking a Senior Principal Product Manager to lead the strategy for Content Discovery. You will influence core customer experiences at a global scale and work with a dynamic team across various functions. The ideal candidate has over 5 years of experience...Senior
$190k - $250k
...Snowflake, Anthropic, Coinbase, and Prudential rely on Zip to manage billions of dollars in spend. We have a world-class team coming... ...Francisco office on a hybrid basis (3 days / week). Your Role As a Product Manager for Enterprise Foundations, you will own the core...SeniorWork at officeHome officeFlexible hours3 days per week$190k - $250k
...Snowflake, Anthropic, Coinbase, and Prudential rely on Zip to manage billions of dollars in spend. We have a world-class team... ...a hybrid basis (3 days / week). Your Role We’re hiring a Senior or Principal Product Manager (experience dependent) to build and on the growth...SeniorWork at officeHome officeFlexible hours3 days per week$175k - $285k
...for self‑monitoring, third‑party risk management, board reporting, and cyber insurance underwriting... .... About The Role We are looking for a Principal Product Manager to own high‑impact product... ...stakeholders, and drive outcomes at a senior level without relying on direct...SeniorTemporary workImmediate start$238.46k
...entertainment company. Our Streaming organization builds the products and platform capabilities that help audiences discover,... ...of brands and products. About the role We are seeking a Senior Principal Product Manager to lead strategy, vision, and execution for Content...SeniorTemporary workLocal areaShift work- ...the real world. A modern, AI-native platform for physical product businesses to manage the flow of goods, dollars, and data in real time, across:... ...with speed, control, and confidence. About the Role As a Senior Product Manager on our Foundations team, you'll own the primitives...SeniorWork at officeImmediate startRelocation packageFlexible hours
$143k - $286k
...work done. We are seeking an AI-native product leader who is deeply fluent in modern AI... ...team enhances product strategy and roadmap management. Collaborating closely with stakeholders... ...cross-functional teams, influencing senior stakeholders, and mentoring product managers...Full timeTemporary workPart time$166.5k - $309.3k
Principal Business Product Manager - Insights & Analytics (Targeting) Genentech • South San Francisco, CA Our Data, Digital, & Analytics (DDA) team partners... ...‑Functional Partnership - Serve as the bridge between senior commercial/business leaders and technical engineering...ApprenticeshipLocal areaImmediate start$166.5k - $309.3k
The Position Principal Business Product Manager - Insights & Analytics (Targeting) Why Genentech We're passionate about delivering on Our Promise to... ...Functional Partnership Serve as the vital bridge between senior commercial/business leaders and deep technical...ApprenticeshipLocal areaImmediate startRelocation package$161.6k - $300k
Principal Business Product Manager - 360 Insights We are looking for a visionary, highly technical Business Product Manager (Director‑level) to join our Insights & Analytics product suite within the 360 Insights pillar. In this role, you will define and execute the strategy...Local areaRelocation package- ...The Opportunity This role is a single-threaded Product Lead: you own a product area end-to-end, drive product-market fit, and operate as the Mini-Founder CEO of your domain. This is a builder-operator role for someone who thrives in ambiguity, ships with urgency, and treats...Local area
$180k - $235k
...Inkitt Product Manager Inkitt is building the Disney of the 21st Century, standing at the forefront of technology and entertainment. Leveraging AI and predictive algorithms, Inkitt discovers unknown stories and turns them into blockbuster hits, producing a new $1M ebook...Work at office$148.1k - $282.1k
...Influence the future of Adobe’s developer ecosystem across automation and AI experiences What You’ll Need to Succeed 8+ years of product management experience building APIs, developer tools, platforms, or enterprise SaaS products Experience defining monetization, packaging...Temporary work$215k - $250k
...best-in-class financing and software products for sustainable solutions, from solar... ...solutions since 2018. We’re looking for a Principal Product Manager who can architect the growth engine... ..., and high signal to stakeholders and senior leadership. Required Skills,...Full time$215.2k - $269k
...future 100 million developers? Are you excited to define the products that AI-native companies will use to build, scale, and... ...prototypes to reliable production systems. We are looking for a Principal Product Manager for Agentic AI Infrastructure to define and own the...Local areaRemote workWorldwideFlexible hours$180k - $245k
...Principal Product Manager Location: Boston, MA OR San Francisco, CA (Hybrid – 2 days/week) Liberate builds AI agents to automate manual tasks... ...-growth enterprise adoption. You will work closely with senior leadership, customers, engineering, design, deployment, and...Flexible hours2 days per week$180k - $195k
...Join to apply for the Principal Product Manager role at Findem Join to apply for the Principal Product Manager role at Findem... ...year All Other Remote US: $180,000 - $195,000 per year Seniority level ~ Seniority level Not Applicable Employment...Full timeTemporary workWork experience placementRemote workHome office$180k - $250k
...Job Title: Principal Product Manager Location: Mountain View, CA Hybrid 2 days/week in office About Us: Witness AI invented intent-based AI security. While legacy tools monitor what users say to AI, we understand what they’re trying to accomplish - stopping jailbreaks,...Work at office2 days per week$200k - $260k
...Circle Treasury Management Product Manager Circle is one of the world's leading internet financial platform companies, building the foundation... ...ability to define product strategy and influence senior stakeholders across technical and business organizations. ~...Flexible hours$228k - $325k
Job Summary NetApp is hiring a principal-level product leader to own the AI product strategy for Azure NetApp Files (ANF)—a first-party, fully managed enterprise file service on Microsoft Azure, delivered in deep partnership between NetApp and Microsoft. In the spirit...Local area$142.8k - $274.8k
...experiences that help people and organizations learn faster, prove what they know, and keep pace with Ai driven work. As a Principal Product Manager , you'll set the vision, shape the roadmap, and lead cross functional teams to deliver delightful, measurable learning...Ongoing contractLocal area$215k - $222k
...of a truly unique global culture at OutSystems! Location: Hybrid in Menlo Park, California OutSystems is seeking a Principal Product Manager to help lead the strategy, roadmap, and execution of our emerging AI Agent platform, Agent Workbench. You'll be a part of...Remote workWorldwideFlexible hours- Genentech is looking for a Principal Business Product Manager to lead their Insights & Analytics product suite. This director-level position involves defining strategies for next-generation data and analytics platforms to empower commercial and medical teams. You will...Senior
- Senior Product Manager - Agentic AI (Hybrid) South San Francisco, United States | Posted on 05/09/2026 Our client, a worldleader in diagnostics and biotechnology, is looking for a Senior Product Manager - Agentic AI based out of South San Francisco, CA (Hybrid). Job...SeniorLong term contract
$210k - $263k
* Principal Product Manager, AI# Principal Product Manager, AISan Francisco, California**Secure Every Identity, from AI to Human**Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations...Flexible hours$240k - $300k
A leading fintech company in San Francisco seeks a Principal Product Manager to define and own a multi-quarter product vision and strategy. The ideal candidate will have 7-10+ years of experience in product management, particularly in high-growth B2B or fintech contexts...- Limelight Health is looking for a Principal Product Manager to drive product strategy and execution, focusing on AI-powered features within the platform. This role involves collaboration across engineering and design to enhance product capabilities that deliver value. The...
- A technology company in San Francisco seeks a Principal Product Manager, AI to lead the Agentic AI strategy and execution. This role involves defining a multi-year AI vision, collaborating with various teams, and ensuring AI agents operate effectively in production environments...
$141.7k - $263.1k
F. Hoffmann-La Roche AG is seeking a Senior Manager for Product Public Relations in South San Francisco. This position focuses on developing communication strategies to engage media and stakeholders while supporting patient access. The ideal candidate will have over 8...Senior- A technology company in benefits administration is seeking a Product Manager in San Francisco to lead the transformation of their benefits administration platform. The role involves defining long-term strategy, collaborating with various departments, and driving execution...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Principal Product Manager. Be the first to apply!
- director new product development South San Francisco, CA
- product launch manager South San Francisco, CA
- global product manager South San Francisco, CA
- product manager beauty South San Francisco, CA
- product manager lighting South San Francisco, CA
- product manager South San Francisco, CA
- hvac product manager South San Francisco, CA
- senior technical product manager South San Francisco, CA
- product manager oncology South San Francisco, CA
- ux product manager South San Francisco, CA

