Bioinformatician / Data Scientist / Computational Biologist focused on RNA Therapeutics

The Biologics Research Center (BRC) is looking for a bioinformatician, a data scientist, or a computational biologist to join the Bioinformatics and Biotherapeutics modeling team in Cambridge, US. About The Role Internal job title: Senior Expert I/II, Data Science Location: Cambridge, MA, onsite One of the key responsibilities is to provide computational, bioinformatic, and statistical support for research and early discovery of RNA therapeutics and RNA platform innovation. Work in a collaborative and multi‑disciplinary environment, translating project needs into bioinformatics solutions, identifying computational needs, and influencing the design of new state‑of‑the‑art analysis techniques. Your Key Responsibilities Provide bioinformatics support to xRNA pipeline and technology projects by collecting, analyzing, integrating in‑silico parameters, screening and omics data to draw relevant and innovative conclusions. Independently design, plan, execute, and document complex data analysis, then interpret, summarize and report findings to help drive decisions and set priorities. Follow latest advances in the field, raise awareness, and influence the introduction of novel state‑of‑the‑art computational techniques. Collaborate in a matrix environment, working with scientists and teams in different areas to address projects’ specific needs and quickly adapt to new technologies and changing needs. Develop user‑friendly applications to make RNA data accessible to bench scientists for broader and repeated use. Communicate data and analyses to a broad scientific audience, technical and non‑technical team members and colleagues. Independently identify and lead, or support, the development of innovative bioinformatics solutions in a matrix environment to answer scientific questions with an impact on the development of next‑generation xRNA therapeutics biology and platform. Essential Requirements PhD in Bioinformatics, Computational Biology, Cheminformatics, or a closely related discipline with a minimum of two years post‑graduate experience, or an MS with a minimum of six years relevant work experience, preferably in industry. Demonstrated experience working with next‑generation sequencing data (Illumina short reads and/or PacBio/Oxford Nanopore long reads), commonly used analysis tools, and ability to develop new pipelines and workflows based on business needs. Strong domain knowledge in molecular biology, computational genomics and transcription gene regulation and/or post‑transcription gene regulation; knowledge and research experience in RNA biology; experience in oligonucleotide therapeutics discovery and/or gene therapy highly desired. Development and application of machine learning algorithms for predictive modeling. Solid programming skills in Python and R, scientific computing with Unix / high‑performance computing environment, including software development practices such as version control, testing, documentation. Strong communication skills (oral and written), ability to multi‑task, and to communicate own results to collaborators with different expertise. Experience integrating, analyzing, visualizing data from different omics sources, high‑throughput screening, and troubleshooting critical issues or problems, determining causes and possible solutions. Ability to monitor and stay up to date on developments within sequencing and genomics to propose improvements and innovation in current workflows. Desired Requirements Knowledge in oligonucleotide chemistry and RNA structure modeling. Experience in lab automation and data management. Salary ranges: Senior Expert I: $126,000–$234,000 USD annually. Senior Expert II: $138,600–$257,400 USD annually. Final salary determined by relevant skills and experience and reviewed periodically. Compensation includes a performance‑based cash incentive and, depending on level, eligibility for annual equity awards. US‑based eligible employees receive a comprehensive benefits package, including health, life and disability benefits, a 401(k) with company contribution and match, and additional benefits. A generous time‑off package includes vacation, personal days, holidays and other leaves. Read our handbook (PDF 30 MB). EEO Statement The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility & Reasonable Accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process or to perform the essential functions of a position, please send an e‑mail to ⟨email protected⟩ or call View phone number on click.appcast.io and let us know the nature of your request and your contact information. Please include the job requisition number in your message. #J-18808-Ljbffr Novartis