Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Sr. Program Manager, Plasmid DNA / Cell and Gene Therapies (Client-Facing)

$150k - $165k

Danaher

Senior Program Manager leading complex plasmid DNA programs for a CDMO, managing strategic client relationships and cross-functional execution from process validation through commercial supply. This client-facing role integrates contractual commitments with technical and operational delivery while reporting to VP of North America Sales.

Responsibilities

  • Lead multi-program portfolios across strategic accounts with concurrent projects, managing timelines, budgets, and cross-functional dependencies
  • Develop and maintain senior-level client relationships, serving as trusted advisor for program direction and partnership outcomes
  • Drive cross-functional alignment and decision-making, resolving competing priorities across manufacturing, quality, regulatory, and finance functions
  • Translate master service agreements and contracts into executable operating requirements; partner on scope changes and commercial protection
  • Establish program governance, track metrics, forecast capacity, and provide regular leadership updates on status, risks, and growth opportunities

Requirements

  • Bachelor's degree required; advanced degree in scientific field strongly preferred
  • 7+ years client-facing project, program, or account management in life sciences
  • 5+ years experience in GMP-regulated CDMO environment preferred
  • Working knowledge of plasmid DNA manufacturing for cell, gene therapy, or genomic medicine
  • Experience managing regulated biotechnology or pharmaceutical programs and contracts
  • Strong analytical and problem-solving skills with risk forecasting ability
Vacancy posted 7 hours ago
Similar jobs that could be interesting for youBased on the Sr. Program Manager, Plasmid DNA / Cell and Gene Therapies (Client-Facing) in Waltham, MA vacancy
  • $125k - $150k

     ...System which makes everything possible.The Program Manager, Precision Medicine and Biopharma...  ...Danaher Diagnostics to bring precision therapies to patients at scale, driving a paradigm...  ...:Leadership of high-priority, external-facing projects and cross-functional teams in... 
    Suggested
    Full time
    Remote work
    Work from home
    Worldwide
    Flexible hours
    Shift work

    Danaher Corporation

    Boston, MA
    4 days ago
  • $212k - $318k

     ...for Cystic Fibrosis (CF), Casgevy, a gene therapy for sickle cell disease and beta-thalassemia and...  ...more than a dozen ongoing research programs focused on the underlying mechanisms...  ...insulin and technologies for insulin management have helped people with T1D manage their... 
    Suggested
    Full time
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    2 days ago
  • $96.17k - $116.24k

     ...data that shapes the future of gene therapy. Job Type: Full Time...  ...dissection of tissues (mammalian cells, non-human primate and mouse...  ...lab experience. Experience in DNA/RNA purification and analysis...  ...experimental documentation and data-management practices. Ability to... 
    Senior
    Full time
    Flexible hours
    Shift work

    Dyno Therapeutics

    Watertown, MA
    5 days ago
  • Catalent is seeking an Account Director, Cell & Gene Therapy to drive new business across our manufacturing network. This field-based, hunter-focused role identifies, pursues, and secures opportunities with biopharmaceutical companies. The Account Director will evaluate... 
    Senior
    Contract work

    Catalent

    Burlington, MA
    1 day ago
  • $126k - $147.5k

     ...Senior Scientist Cell Pharmacology Xilio Therapeutics is a clinical...  ...immuno-oncology (I-O) therapies with the goal of significantly...  ...decision-driving data that drive our programs forward. This role provides an...  ...assays and reporter gene assays (RGA) which assess drug... 
    Senior
    Full time

    Xilio Therapeutics

    Waltham, MA
    11 days ago
  • $130k - $150k

     ...Description The field of gene therapy is growing rapidly...  ...needs of our clients. We provide...  ...vectors, and provide cell transduction for gene...  ...Engineering Manager/Sr. Manager is responsible...  ...implementing program enhancements and overseeing...  ...during client facing project meetings... 
    Senior
    Work experience placement
    Live in
    Visa sponsorship

    Genezen

    Lexington, MA
    23 days ago
  •  ...Responsibilities • Work with team members to drive forward new gene therapy programs • Perform cell culture and molecular biology experiments and establish...  ...vitro and in vivo. • Establish and characterize Client assays for endpoint analysis to in vivo studies •... 
    Senior
    Full time
    H1b
    Visa sponsorship
    Work visa

    Saviance

    Boston, MA
    6 days ago
  • $125k - $150k

     ...Program Manager role within Danaher Diagnostics' Precision Medicine and Biopharma Solutions group, responsible for executing high-priority...  ...arrangement. Responsibilities Lead high-priority external-facing projects and cross-functional teams ensuring on-time, on-... 
    Remote work

    Danaher

    Boston, MA
    4 days ago
  • $125.1k - $225.2k

     ...Senior Rail & Transit Operations Planning Program Manager to join our growing Rail and Transit...  ...expertise with the ability to cultivate client relationships and drive strategic growth...  ...Build and P3Proven track record in client-facing and industry roles at all levelsCombination... 
    Senior
    Full time
    Contract work
    For contractors
    Flexible hours

    Parsons

    Boston, MA
    4 days ago
  •  ...developing transformative gene-based medicines for...  ...world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-...  ...achieving outcomes for our R&D programs. This person will join a strong program management team in the Boston, MA... 
    Senior
    Remote work

    CRISPR Therapeutics

    Boston, MA
    8 hours ago
  • $268.2k - $402.2k

     ...implementation of innovative global regulatory strategies for product development and commercialization of programs within the T1D portfolio. This position will manage a group of global/regional regulatory professionals with program leadership responsibilities. This role... 
    Full time
    Summer work
    Local area
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    1 day ago
  • $227k - $283.79k

     ...commercialization of transformative therapies for patients with...  ...present across B cell lineage, to inhibit...  ...Zenas’ earlier stage programs include ZB021, a clinical...  ..., and lifecycle management of assetsServe as biomarker...  ...)Serve as external-facing scientific leader in biomarker... 
    Senior

    Zenas BioPharma

    Waltham, MA
    4 days ago
  • $154.4k - $242.55k

     ...Senior/Principal Scientist, Cell Based-Potency Assay Development...  ...serve as a consultant to management and an external spokesperson...  ...management across biologics programs. You will translate mechanism...  ...biologics, vaccines, cell therapy, gene therapy, or related modalities... 
    Senior
    Minimum wage
    Contract work
    Local area

    Takeda

    Lexington, MA
    4 days ago
  • $123.4k - $158.67k

     ...access, afford and remain on the therapy they need for a better...  ...who need them-faster. What Program Managers contribute to Cardinal...  ...relationship with an assigned set of clients in order to achieve the...  ...working knowledge of client-facing and industry trends as well... 
    Full time
    Temporary work
    Work at office
    Local area
    Immediate start
    Flexible hours

    Cardinal Health

    Boston, MA
    1 day ago
  • $166k - $220k

     ...Senior Technical Program Manager Anduril Industries is a defense technology company with a mission...  ...teams, and meticulous planning in the face of ambiguity. Your ability to...  ...and/or pivot deployment as needed to meet client needs. Successfully developing our complex... 
    Senior

    anduril

    Waltham, MA
    3 days ago
  •  ...perform in vitro experiments to characterize leading capsids and libraries. You will work with a cross-functional team of scientists, optimize workflows, troubleshoot issues, and ensure high-quality data to inform gene therapy programs. #J-18808-Ljbffr Dyno Therapeutics
    Senior

    Dyno Therapeutics

    Watertown, MA
    5 days ago
  • $92k - $103k

     ...the next generation of gene editing therapies to patients. The...  ...while minimizing unwanted DNA modifications, Prime Editors...  ...tissues, organs and cell types. Prime...  ...investigational therapeutic programs organized around our...  ...inspection. The role manages the vendors who calibrate... 
    Full time
    Temporary work

    Prime Medicine

    Watertown, MA
    2 days ago
  • $122.25k - $176.58k

     ...development of life-changing advanced cell and gene therapy products, including...  ...carries no direct people management responsibilities, the incumbent...  ..., prevention and wellness programs and at least 14 weeks’ gender...  ...difference. Reinvention is in our DNA. It’s what drove our... 
    Full time

    Sanofi Group

    Watertown, MA
    5 days ago
  • $150k - $200k

     ...realize the potential of their therapies from design to...  ...regulatory standards for our cell and gene therapy programs transitioning from early clinical...  ...Development, QC management, QC testing, and QA teams,...  ...industry standards, as well as client requirements.Collaborate with... 
    Senior

    ElevateBio

    Waltham, MA
    7 hours ago
  • $149k - $166k

     ...the next generation of gene editing therapies to patients. The...  ...while minimizing unwanted DNA modifications, Prime Editors...  ...tissues, organs and cell types. Prime Medicine...  ...therapeutic programs organized around our core...  ...Position SummaryThe Senior Manager, Regulatory Operations... 
    Senior
    Full time
    Temporary work

    Prime Medicine

    Somerville, MA
    2 days ago
  • $166k - $220k

     .... ABOUT THE JOB As a Technical Program Manager working on our Intelligence Surveillance...  ...teams, and meticulous planning in the face of ambiguity. Your ability to collaborate...  ...and/or pivot deployment as needed to meet client needs. Successfully developing our... 
    Senior
    Full time
    Work experience placement
    Immediate start

    Anduril Industries

    Waltham, MA
    3 days ago
  • $268.2k - $402.2k

     ...Pharmaceuticals seeks an experienced regulatory leader to develop and implement global regulatory strategies for Type 1 Diabetes programs. This executive role manages a team of regulatory professionals across multiple development stages and represents regulatory input on senior... 

    Vertex Pharmaceuticals

    Boston, MA
    11 days ago
  • $100k - $200k

     ...sciences companies bring therapies to patients faster. As one...  ...will be at the center of managing all customer-facing teams and coordinating closely...  .... As the Global Program Manager, you will own customer...  ...areas for enterprise pharma clients ~ Track record of... 
    Contract work
    Work at office
    Local area
    Remote work
    Work from home
    Home office
    Flexible hours
    3 days per week

    Veeva Systems

    Boston, MA
    2 days ago
  • $140k - $165k

     ...Description The field of gene therapy is growing rapidly and...  ...exacting needs of our clients. We provide process...  ...vectors, and provide cell transduction for gene...  ...components and software, manage virtual servers, and...  ...accelerating our partners' programs. R esilience &... 
    Senior
    Live in
    Visa sponsorship

    Genezen

    Lexington, MA
    a month ago
  • $126k - $181.5k

     ...inspire next-generation therapies and uncover novel...  ...and build the DNA and oligo libraries...  ...expression in mammalian cells. We're looking for...  ...biology and plasmid engineering at scale...  ...Experience with synthetic gene / oligo-pool...  ..., annual incentive program, retirement benefits... 
    Senior

    Seres Therapeutics

    Cambridge, MA
    3 days ago
  • $130k - $150k

     ...Description The field of gene therapy is growing rapidly and...  ...exacting needs of our clients. We provide process...  ...vectors, and provide cell transduction for gene...  ...JOB SUMMARY The Manager/Sr. Manager, Validation -...  ...Supports the Data Integrity program to ensure that GxP... 
    Senior
    Contract work
    Live in
    Work at office
    Visa sponsorship

    Genezen

    Lexington, MA
    15 days ago
  • $126.2k - $264.1k

     ...Job Description Manage the development and implementation process of a specific company...  ...monitor work of systems analysis and program staff, providing technical support and direction...  ...Certain U.S. based or U.S. customer or client-facing roles may be required to comply with... 
    Senior
    Temporary work
    Flexible hours

    Oracle

    Boston, MA
    4 days ago
  • $140k - $170k

     ...groundbreaking therapies. Our mission is...  ...Commercial Product Manager is responsible...  ...’s expanding Gene Editing...  ...product lead for key client discussions and...  ...preferred (e.g. cell biology, molecular...  ...in a client-facing role as a product...  ...benefit programs that add value... 
    Senior
    Full time
    Remote work
    Work from home
    Flexible hours

    Danaher Corporation

    Boston, MA
    7 hours ago
  • $307k - $325.35k

     ...AG, is a leading engineered cell therapy company pioneering a new generation...  ...our proprietary CELL+GENE™ platform, we direct cellular...  ...Senior Director/Vice President, Program Team Leader is the single point...  ...in partnership with Program Management and Finance. Ensure compliant... 
    Senior
    Worldwide
    Shift work

    BlueRock Therapeutics LP

    Cambridge, MA
    2 days ago
  • $190k - $240k

     ...company, is a global gene therapy leader focused on transforming...  ...hematopoietic stem cells (HSCs). Orchard has...  ...Science Liaison (Sr MSL) is a therapeutic...  ...gene therapy clinical programs. They demonstrate leadership...  ...balanced with risk management within the boundaries... 
    Senior
    Full time
    Local area
    Remote work

    Orchard Therapeutics

    Boston, MA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Sr. Program Manager, Plasmid DNA / Cell and Gene Therapies (Client-Facing). Be the first to apply!