Senior Principal Process Control & Automation Engineer
$66k - $171.6kEli Lilly & Co
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Lilly is currently constructing an advanced manufacturing facility for production of Active Pharmaceutical Ingredient (API) molecules located in Lebanon, Indiana, USA. This facility is Lilly’s largest investment in manufacturing capacity and is intended to provide APIs for current and future products. This is a unique opportunity to be a part of the team for the startup of a greenfield manufacturing site, and the successful candidate will help to build the organization, the facility, and the culture to enable a successful startup into GMP manufacturing operations. Overview The Process Control and Automation Engineer is responsible for the development, implementation, improvement, verification, and qualification of process control and automation solutions. This includes all activities necessary to support automation solutions in production, as well as area‑engineering initiatives such as commissioning, qualification, process improvements, solution enhancements, and troubleshooting. The PCAE – Application Enhancement (PCAE‑AE) focus area is responsible for managing and implementing hardware and software application upgrades, including control strategies, recipes, and process data collection models, along with supporting validation, qualification, and verification of those deliverables. Responsibilities Manage and implement HW/SW application upgrades and updates, including control strategies, recipes, and process data collection models Support validation, qualification, and verification of application deliverables Maintain up‑to‑date documentation packages for all applications Work safely in accordance with all HSE standards Perform all activities in compliance with GMPs and applicable procedures Stay closely aligned with the process team as an active, participating member — understanding priorities, issues, and objectives, and responding to team decisions Develop system requirements and designs Manage and develop code in a GMP‑compliant manner Deliver projects on time and execute changes that keep systems reliable, current, and compliant Appropriately prioritize activities to maximize overall business impact Understand and apply GMP concepts to influence procedure development Contribute to continuous improvement efforts, including equipment reliability Perform other tasks as assigned by supervisor Basic Requirements Bachelor’s degree in Engineering, Computer Science, or a related field 10+ years of experience as a Process Automation Engineer or Process Engineer Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role. Additional Preferences Computer System Validation (CSV) experience is desirable Strong interpersonal and communication skills with the ability to work effectively in a team environment Willingness to learn areas outside of core automation responsibilities Ability to develop expertise in production processes, equipment‑specific code, and control system technologies (software, hardware, and field instrumentation) Automation Platform Experience: Emerson: DeltaV Operator, Live, Batch, AMS, Historian, Simulate, Simulate Pro, MIMIC Simulation Platform Rockwell: Studio 5000, Logix, FactoryTalk SE/ME/Asset Center, Historian AVEVA PI: PI Historian, PI Vision, Event Frameworks Johnson Controls: Metasys VE Logmate IT Platform Support Experience: Server administration and health monitoring LAN/network support and troubleshooting Virtual hardware setup and administration Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( ) for further assistance. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $66,000 – $171,600. Full‑time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company‑sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #J-18808-Ljbffr Eli Lilly and Company
- Senior Industrial Automation & Controls Engineer (PLC / SCADA) We are looking for a Senior Industrial Automation & Controls Engineer to join our team onsite... ...or production support. About PACIV PACIV stands for Process Automation, Controls, Instrumentation, & Validation....SeniorFull timeContract workTemporary workImmediate start
$111k - $178.2k
A global healthcare leader is seeking a Sr. Principal Process Safety Management Engineer in Indianapolis, IN. The role involves providing process safety engineering support, collaborating with cross-functional teams, and ensuring operational readiness at new manufacturing...PrincipalSenior- Initial Therapeutics, Inc. is looking for an Aseptic Process Engineer to provide expert process engineering support globally. This position is responsible for offering technical resources in Aseptic Processing and developing solutions for various manufacturing sites worldwide...PrincipalSeniorWorldwide
- A global healthcare leader is seeking a Process Safety Engineer to support their API/Dry Product Network in Indianapolis. The role involves providing engineering support during site start-ups, ensuring operational readiness, and fostering a strong safety culture. Required...PrincipalSenior
$64.5k - $143k
Eli Lilly and Company is seeking an Automation Engineer to support various automation needs across manufacturing. The role involves technical leadership and mentoring, focusing on effective process control and systems integration. Candidates should have at least a B.S....Senior- A global healthcare leader in Indianapolis, Indiana seeks an Engineer for the ADN RAMP Team. This mid-senior level role requires expertise in process control and automation to support new site start-ups. Candidates should possess a BS degree in Engineering along with 8-...Senior
$66k - $171.6k
...make life better for people around the world. The Senior Principal Engineer - Automation Engineering will work as a member of the Automation... ...projects, with primary focus on Instrumentation and Control Hardware. Process Automation is core to delivering the right first-time...PrincipalSeniorFull timeWork experience placementRemote workFlexible hours$66k - $171.6k
Eli Lilly and Company is seeking a Process Control and Automation Engineer for their new manufacturing facility in Lebanon, Indiana. The role involves managing application upgrades, ensuring compliance with GMP standards and collaborating on engineering initiatives. Qualified...Senior- ...global healthcare firm in Indianapolis is looking for a Senior Principal Engineer - Automation Engineering. This role involves providing automation... ...mentoring team members, and overseeing the implementation of control systems. Candidates should have a B.S. in Engineering...PrincipalSeniorFull time
- ...healthcare company is seeking a Sr Manufacturing Engineer - Controls in Indianapolis. This role involves providing technical support for automated manufacturing equipment, troubleshooting issues, and enhancing manufacturing processes related to diabetes management. The ideal...Senior
- A leading environmental solutions company in Indianapolis is seeking a Controls Engineer to configure, program, and manage HVAC building automation systems. The ideal candidate will hold a Bachelor's degree in mechanical engineering and have over three years of hands-on...Senior
$87k - $222.2k
Initial Therapeutics, Inc. is seeking a hands-on engineer to integrate agentic AI with laboratory automation systems in Indianapolis, Indiana. The role involves rapid prototyping and scaling AI-driven workflows to enhance molecule discovery. Candidates should hold a PhD...PrincipalSenior$114k - $198k
...Director. Key Objectives/Deliverables: Provide Peptide API process engineering expertise to the Global Facility Delivery team and the Site... ...problem solving skills. Collaborative skills with operations, automation, and other process team members. Ability to coach others....PrincipalSeniorTemporary workLocal areaRelocationFlexible hoursShift work- ...a candidate experienced in programming Distributed Control Systems (DCS) for industrial automation projects. The role includes developing control strategies... ...should have a Bachelor's degree in Electrical Engineering and 3-5 years in DCS programming or controls engineering...Senior
- ...alidation PACIV is seeking an experienced DeltaV Batch Automation & Controls Engineer to support production‑critical Emerson DeltaV systems... ...Support automation for manufacturing and skid‑based process systems Troubleshoot and optimize systems in cGMP production...Full time
- ...Full-Time | Direct Hire We are looking for a hands-on Automation Controls Engineer with strong Siemens PLC experience to support on-site... ...equipment skid integration within larger manufacturing and process control systems Develop clear, compliant documentation...Full timeImmediate start
- Liberty Personnel Services, Inc. is seeking a highly experienced Lead Controls Engineer to manage electrical controls and automation projects in the water and wastewater sector. This role requires strong expertise in industrial controls systems, programming PLCs and HMIs...Senior
- ...Indianapolis, IN. This role provides technical expertise in delivering pharmaceutical medicines and ensures compliance in manufacturing processes. The successful candidate must have a Master’s degree in Chemistry or a related field, with over 8 years of relevant industry...PrincipalSenior
$117k - $209k
...communities through philanthropy and volunteerism. Responsibilities The Engineering Tech Center is responsible for providing global technical expertise in the engineering sciences related to Process Engineering and secondary/tertiary loop disciplines. This includes...PrincipalSeniorFull timeContract workTemporary workCasual workH1bVisa sponsorshipWork visaFlexible hours$111k - $178.2k
...Team Sr. Director. Key Objectives/Deliverables Provide process safety engineering support to the Global Facility Delivery team and the Site... ...support, on‑floor process support, document reviews, change controls. Support the roll out of process safety management (PSM)...PrincipalSeniorFull timeTemporary workH1bLocal areaRelocationVisa sponsorshipWork visaFlexible hoursShift work- Initial Therapeutics, Inc. is seeking a Principal Automation Integration Engineer in Indianapolis, IN. This role focuses on integrating data between various teams using process automation technologies. The ideal candidate will have a Bachelor's degree in Engineering or...Principal
- Description As our Senior/Principal Reliability Coordination Trainer , you will help support... ...demonstrate technical acumen of MISO's processes, procedures, and tools You developed... ...Coordinator and/or familiarity with MISO control room tools Demonstrated experience...PrincipalSeniorTraineeship
- BioSpace is hiring a Sr Specialist- Warehouse - Engineering in Indianapolis, responsible for monitoring automated storage and retrieval systems and ensuring the reliability of production processes. Candidates should have an Associate's Degree and 5 years of manufacturing...SeniorFull time
$79.5k - $148.5k
Initial Therapeutics, Inc. is seeking a Principal Process Engineer for Biologics Drug Product Development in Indianapolis, Indiana. The role involves developing parenteral drug product manufacturing processes and collaborating with cross-functional teams to ensure successful...Principal$138.9k - $191k
Humana Inc is seeking a Financial Planning & Analysis Principal to analyze financial data and provide strategic... ...This fully remote role involves working closely with senior leadership to aid decision-making processes and operational changes. Candidates must have at least...PrincipalSeniorRemote job$87k - $222.2k
...our mindset, technology, and processes for faster, more nimble execution... ...scientific agentic AI, lab automation, and unified data platforms... ...laboratory science. You will engineer the connective tissue between... ...Kubernetes with laboratory control systems External Engagement...PrincipalSeniorFull timeFlexible hours- What is the role about? A mid-level Process Automation Engineer has a passion for solving customer problems by designing innovative and robust solutions... ...individual will apply their passion for automation and controls combined with Endress+Hauser measurement instrumentation...
$83.2k - $154.5k
Sr Manufacturing Engineer - Controls page is loaded## Sr Manufacturing Engineer... ...engineering support of automated and semi-automated manufacturing... ...troubleshoot equipment and process issues, lead/contribute to... ...expected salary range for the Senior Manufacturing Engineer...SeniorLocal areaRelocation packageNight shiftRotating shiftWeekend work- T2 Systems, Inc. is seeking an Automation QA Engineer in Indianapolis, IN. This role demands hands-on skills in automation and engineering to... ...identifying improvements in testing, and maintaining CI/CD processes. Strong knowledge of QA practices, problem-solving skills,...Senior
- Parking Network BV in Indianapolis, Indiana is seeking an Automation QA Engineer. This role focuses on designing scalable automation solutions... ...in Python, as well as knowledge of ISTQB testing processes, is highly sought after. A strong communication skill set is...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Principal Process Control & Automation Engineer. Be the first to apply!
- director data engineering Indianapolis, IN
- senior civil engineer project manager Indianapolis, IN
- principal cloud engineer Indianapolis, IN
- engineering director Indianapolis, IN
- principal infrastructure engineer Indianapolis, IN
- principal network engineer Indianapolis, IN
- chief engineer Indianapolis, IN
- civil engineer project manager Indianapolis, IN
- data center chief engineer Indianapolis, IN
- principal data engineer Indianapolis, IN


