Nurse Practitioner / Physician Assistant - Weekend Clinical Research - Chandler, AZ

Job Description

Job Description

Nurse Practitioner / Physician Assistant - Weekend Clinical Research - Chandler, AZ - Friday–Sunday 3/12s with Monday–Thursday Off

If you want your Mondays through Thursdays back, this is the schedule that makes it possible. Three 12-hour shifts, Friday through Sunday, in a Phase 1 clinical research and specialty GI practice — full-time pay, full benefits, and four consecutive days off every single week.

Overview & Highlights:

• Location: Chandler, AZ — East Valley, minutes from the 101 and 202 corridors
• Schedule: Three 12-hour shifts (3/12s), Friday–Sunday, with Monday–Thursday off
• Employment Type: Full-time, exempt — direct-hire employee
• Compensation: $130,000–$155,000 per year, depending on experience
• Focus: Phase 1 clinical research, hepatology, and gastroenterology
• Reports To: VP of Research
• Benefits: Medical, dental, and vision insurance; HSA plan options with employer contribution; 4 weeks of PTO; 5 days of sick time; 7 company holidays plus 2 half-days; CME budget and CME time off; 401(k) with 6% company match; short- and long-term disability coverage; shared company vehicles for required business travel
• Sign-On / Relocation Bonus: Available for eligible candidates
• Experience: Previous clinical research experience and at least 1 year practicing as an NP or PA required

Location & Logistics:

• Work Environment: On-site Phase 1 clinical research and specialty patient care setting
• Coverage Model or Hours: Friday, Saturday, and Sunday, three 12-hour shifts per week
• Weekly Structure: Three scheduled workdays, with Monday through Thursday off
• Travel: No routine travel required; occasional interoffice travel may be requested, with a company vehicle or mileage reimbursement provided
• On-Call: Participation in the NP/PA call rotation as applicable

About the Opportunity / A Day in the Life:

We are looking for an experienced Nurse Practitioner or Physician Assistant to join our Phase 1 clinical research team in Chandler, AZ on a weekend schedule. This is a specialized role for a provider who already understands protocol-driven care and wants hands-on involvement in evaluating emerging therapies while caring for patients with chronic hepatic and gastrointestinal conditions.

Working three 12-hour shifts from Friday through Sunday, you will evaluate and manage both standard-of-care and clinical research patients — conducting consultations and pretreatment reviews, performing medical and safety assessments, and supporting patients through every stage of their trial participation.

You will practice in a Sub-Investigator capacity, working closely with physicians, clinical research coordinators, recruiters, and other research professionals. Day to day that means knowing your assigned protocols cold, completing research visits, reviewing source documentation and informed consent records, and making sure every clinical decision lines up with patient safety and study requirements.

This is a hands-on role with real patient and study ownership. You will follow your patients from initial evaluation through study completion and closeout, and your clinical judgment will directly shape both the care they receive and the quality of the data behind it.

Why This Role Stands Out:

• A true three-day workweek — Friday, Saturday, and Sunday, then four consecutive days off
• Monday through Thursday free every week , which makes room for family, a second commitment, teaching, or a genuinely compressed work life
• Direct involvement in Phase 1 clinical trials and emerging therapies, not just enrollment support
• Sub-Investigator responsibility with meaningful ownership of your own research patients
• Specialized exposure to hepatology, gastroenterology, and chronic hepatic disease
• A rare combination of autonomous clinical practice, research, and multidisciplinary collaboration

What We’re Looking For:

• An NP or PA with previous clinical research experience
• Strong command of research protocols and clinical trial processes
• Working knowledge of what serving as a Sub-Investigator actually requires
• The ability to manage clinically complex patients independently
• Close attention to research documentation, patient safety, and protocol compliance
• A resourceful problem-solver who collaborates well across clinical and research teams
• Genuine availability and preference for a Friday–Sunday schedule

Job Duties & Responsibilities:

• Perform patient evaluations, consultations, and pretreatment reviews for standard-of-care and clinical research patients.
• Serve in a Sub-Investigator capacity and support the clinical execution of Phase 1 research protocols.
• Oversee appropriate aspects of clinical trial patient care and perform medical and safety reviews.
• Diagnose conditions and make appropriate treatment decisions within your established scope of practice.
• Educate patients on therapeutic options available through applicable hepatology clinical trials.
• Counsel patients and families and collaborate with physicians on appropriate direct-care interventions.
• Serve as a primary clinical point of contact and take responsibility for managing assigned patients.
• Partner with clinical research coordinators, recruiters, physicians, and other research personnel to complete study visits.
• Review source documentation, clinical charting, informed consent records, and study documentation for accuracy and completeness.
• Maintain a thorough understanding of assigned protocols and communicate study requirements to the research team.
• Perform applicable in-clinic procedures, including FibroScan, when appropriately trained and qualified.
• Support assigned patients and studies from initial evaluation through study completion and closeout.

Required Qualifications:

• Graduate of an accredited Nurse Practitioner or Physician Assistant program
• Current applicable NP or PA certification
• Active or eligible license to practice in AZ
• Nurse Practitioner candidates must maintain current applicable RN and NP licensure and certification
• Physician Assistant candidates must maintain applicable NCCPA certification
• Previous clinical research experience with a strong understanding of research processes and protocols
• At least 1 year of experience practicing as an NP or PA in a clinic or hospital setting
• Availability to work Friday, Saturday, and Sunday 12-hour shifts
• Ability to diagnose and manage clinically complex patients with minimal assistance
• Strong verbal, written, and interpersonal communication skills
• Ability to complete GCP and IATA training upon hire
• Ability to maintain all certifications required by the applicable department or division
• Valid documentation and authorization to work in the United States

Preferred Background:

• Previous outpatient gastroenterology and/or hepatology experience
• Previous Sub-Investigator experience
• Phase 1 clinical trial experience
• Experience caring for patients with chronic hepatic disease
• Experience independently performing FibroScan procedures
• Bilingual English/Spanish skills
• Leadership or mentoring experience within clinical research, including coaching research personnel on standard operating procedures and best practices
• Comfort with electronic medical record systems, including eCW, and with Microsoft Outlook, Word, Excel, PowerPoint, and OneDrive
• Commitment to continued professional development and additional certifications

This Role Is Likely a Fit If You…

• Want a three-day workweek with Monday through Thursday off.
• Have clinical research experience and understand protocol-driven patient care.
• Want direct involvement in Phase 1 clinical trials and emerging therapies.
• Enjoy combining advanced clinical practice with research responsibilities.
• Are comfortable managing complex patients with a high degree of autonomy.
• Thrive in a collaborative environment alongside physicians and clinical research professionals.

This Role May Not Be a Fit If You…

• Are unavailable to consistently work Friday, Saturday, and Sunday.
• Need a Monday–Friday schedule or your weekends free.
• Do not have previous clinical research experience.
• Prefer a traditional outpatient position without research or protocol responsibilities.
• Are uncomfortable with detailed source documentation and regulatory requirements.
• Are looking for a fully remote or hybrid position.

Why Join Us:

This position offers an uncommon combination: Phase 1 clinical research, specialty medicine, real patient ownership, and a three-day workweek. You will contribute directly to trial execution and patient safety, and you will do it alongside an experienced multidisciplinary research team that takes the work seriously.

The Friday–Sunday 3/12 schedule gives you four consecutive days off every week, while the clinical scope lets you deepen real expertise in research, gastroenterology, and hepatology. If you are an experienced NP or PA with clinical research experience looking for a specialized role and a genuinely different schedule, please apply with your most updated Resume/CV. We look forward to meeting you!