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Senior Principal Architect, Solution Architecture

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Our team members are at the heart of everything we do. At Cencora, we are united in our responsibility to create healthier futures, and every person here is essential to us being able to deliver on that purpose. If you want to make a difference at the center of health, come join our innovative company and help us improve the lives of people and animals everywhere.

Job Details Summary

Defines enterprise solution architecture direction across interdependent domains, translating long-term business and technology strategy into scalable, secure, resilient, and supportable solution approaches. Provides strategic leadership for multi-cloud architecture initiatives across Azure and AWS platforms, ensuring alignment to enterprise standards, security requirements, and business objectives. Guides the organization on the highest-complexity architecture decisions, setting standards, governance, and quality expectations that shape execution at enterprise scale. Partners closely with product, engineering, and business stakeholders to ensure technology investments are prioritized and delivered with a product ownership mindset focused on measurable business outcomes. Communicates technical strategy, tradeoffs, and decision agendas clearly with senior leaders, cross-functional stakeholders, and external parties as needed. Applies deep healthcare technology domain expertise to design solutions that support regulatory, operational, interoperability, security, and patient-centric business requirements.

Job Responsibilities

  • Cloud Architecture & Strategy Define and govern enterprise solution architectures across Microsoft Azure and Amazon Web Services (AWS) environments, establishing standards, patterns, and best practices for scalability, security, reliability, and cost optimization. Lead cloud modernization and transformation initiatives leveraging Azure and AWS native services, platform capabilities, and cloud governance frameworks.
  • Healthcare Technology Leadership Apply deep knowledge of healthcare technology ecosystems, healthcare operations, interoperability standards, regulatory requirements, data privacy, security, and compliance considerations to solution design and architecture decisions. Guide architecture decisions that support healthcare business capabilities, patient and provider experiences, clinical workflows, data exchange, analytics, and operational excellence.
  • Technical Product Ownership & Stakeholder Engagement Partner closely with product managers, business leaders, and engineering teams to translate business strategies, customer needs, and operational challenges into technology roadmaps and enterprise solutions. Demonstrate a technical product ownership mindset by balancing business value, technical feasibility, scalability, cost, risk, and delivery considerations while driving architecture decisions. Facilitate collaboration across product, engineering, architecture, and business stakeholders to establish priorities, align roadmaps, and ensure successful solution outcomes.

Required Qualifications

  • Bachelor's degree in Computer Science, Data Science, Software Engineering, Systems Engineering, Information Technology, or a related field, or equivalent experience required.
  • 10+ years of experience in software engineering, systems engineering, solution architecture, cloud architecture, or related fields.
  • 8+ years of experience within a lead or principal position
  • Demonstrated experience designing, implementing, and governing enterprise-scale solutions across Microsoft Azure and AWS cloud platforms.
  • Proven experience partnering with business, product, and technology organizations to deliver strategic technology solutions with a technical product ownership and customer-centric mindset.
  • Significant experience within the healthcare technology industry, including healthcare applications, data platforms, interoperability, security, and regulatory requirements.

Preferred Qualifications

  • Master's degree in Computer Science, Data Science, Software Engineering, Systems Engineering, Information Technology, or a related field, or equivalent experience preferred.
  • Azure certifications (e.g., Azure Solutions Architect Expert) and AWS certifications (e.g., AWS Certified Solutions Architect Professional) preferred.
  • Experience supporting healthcare organizations, health systems, providers, payers, life sciences, MSOs, or related healthcare technology environments.
  • Certification in solution architecture, cloud architecture, enterprise architecture, or equivalent preferred.

What Cencora offers

  • medical
  • dental
  • vision care
  • backup dependent care
  • adoption assistance
  • infertility coverage
  • family building support
  • behavioral health solutions
  • paid parental leave
  • paid caregiver leave
  • training programs
  • professional development resources
  • mentorship programs
  • employee resource groups
  • volunteer activities

We provide compensation, benefits, and resources that enable a highly inclusive culture and support our team members’ ability to live with purpose every day. In addition to traditional offerings like medical, dental, and vision care, we also provide a comprehensive suite of benefits that focus on the physical, emotional, financial, and social aspects of wellness. This encompasses support for working families, which may include backup dependent care, adoption assistance, infertility coverage, family building support, behavioral health solutions, paid parental leave, and paid caregiver leave. To encourage your personal growth, we also offer a variety of training programs, professional development resources, and opportunities to participate in mentorship programs, employee resource groups, volunteer activities, and much more. For details, visit

Full time

Equal Employment Opportunity

Cencora is committed to providing equal employment opportunity without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, age, disability, veteran status or membership in any other class protected by federal, state or local law. The company’s continued success depends on the full and effective utilization of qualified individuals. Therefore, harassment is prohibited and all matters related to recruiting, training, compensation, benefits, promotions and transfers comply with equal opportunity principles and are non-discriminatory. Cencora is committed to providing reasonable accommodations to individuals with disabilities during the employment process which are consistent with legal requirements. If you wish to request an accommodation while seeking employment, please call View phone number on click.appcast.io or email View email address on click.appcast.io. We will make accommodation determinations on a request-by-request basis. Messages and emails regarding anything other than accommodations requests will not be returned.

Affiliated Companies

ASD Specialty Healthcare LLC

Cencora overview

Cencora is a leading global pharmaceutical solutions company that is committed to improving the lives of people and animals everywhere. We connect manufacturers, providers, and patients to ensure that anyone can get the therapies they need, where and when they need them. We’re a purpose-driven organization, where all of our team members around the world are united in our responsibility to create healthier futures. We work together every day to help our partners bring their innovations to patients worldwide, creating unparalleled access and impact at the center of health.

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